Search Business Hotels in Mexico and Central America
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Mexico and Central America Business Hotels
Our top choices for Mexico and Central America business-friendly hotels
Hyatt Place Panama City/Downtown
Hyatt Place Panama City/DowntownPanama City
8.6 out of 10, Excellent, (1000)
"Horrible. The establishment was closed (August 2021) when we arrived. The hotel charged my credit card only to find out when we arrived, the hotel was empty and abandoned. Never again!"
John
9.0 out of 10, Wonderful, (4731)
"The rooms were nice and the food was great..great staff!!"
Tffany
The price is ฿3,800
฿4,181 total
includes taxes & fees
12 Jan - 13 Jan 2026
9.4 out of 10, Exceptional, (3228)
"Excellent stay "
Arturo
The price is ฿3,721
฿4,447 total
includes taxes & fees
26 Jan - 27 Jan 2026
9.4 out of 10, Exceptional, (2112)
"Excellent location and restaurants"
Nazanin
The price is ฿7,413
฿8,858 total
includes taxes & fees
2 Jan - 3 Jan 2026
9.2 out of 10, Wonderful, (2152)
"Very nice hotel. I really enjoyed my stay there."
Rina Vazquez
The price is ฿5,115
฿6,112 total
includes taxes & fees
18 Jan - 19 Jan 2026
9.4 out of 10, Exceptional, (1344)
"Great stay"
Carlos
The price is ฿7,043
฿8,417 total
includes taxes & fees
17 Jan - 18 Jan 2026
9.2 out of 10, Wonderful, (3118)
"Breakfast with room service was very good."
Gary
The price is ฿2,541
฿3,100 total
includes taxes & fees
25 Jan - 26 Jan 2026
8.8 out of 10, Excellent, (11949)
"Convenient and comfortable hotel right at the airport. Great staff, clean rooms and a great night sleep!"
Charles
The price is ฿4,593
฿5,489 total
includes taxes & fees
8 Jan - 9 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Mexico and Central America Hotel Reviews
Live Aqua Cancun - Adults Only - All-Inclusive
10/10 Excellent
