Santo Spirito Travel Guide

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

Things to do


Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
The price is ąøæ4,923 per night from 3 Nov to 4 Nov
ąøæ4,923
ąøæ5,944 total
3 Nov - 4 Nov
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
The price is ąøæ3,708 per night from 4 Nov to 5 Nov
ąøæ3,708
ąøæ4,608 total
4 Nov - 5 Nov
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Piazza del Duomo ...
9.2/10 Wonderful! (338 reviews)
"The hotel was clean and spacious for a Florence hotel. Roxy the host was extremely helpful and pleasant she provided some areas to eat and to see sunset at piazza Michelangelo"

Reviewed on 5 Oct 2026

La Torre Del Cestello
Hostel Santa Monaca

Hostel Santa Monaca

Via Santa Monaca 6 Florence FI
The price is ąøæ2,375 per night from 5 Nov to 6 Nov
ąøæ2,375
ąøæ2,915 total
5 Nov - 6 Nov
includes taxes & fees
Stay at this hostel in Florence. Enjoy free Wi-Fi, daily housekeeping and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza del ...
7.8/10 Good! (64 reviews)
"No"

Reviewed on 30 Jul 2026

Hostel Santa Monaca
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
The price is ąøæ3,988 per night from 3 Nov to 4 Nov
ąøæ3,988
ąøæ4,915 total
3 Nov - 4 Nov
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and premium bedding. Our guests praise the helpful staff in their reviews. Popular attractions ...
9.2/10 Wonderful! (1,185 reviews)
"The property was located in Santo Spirito section which is near (walking distance) to the Pontevecchia and Pitti Palace with great restaurants. The apartment itself was ok. Extremely loud from neighbors walking around and moving furniture. And construction outside.Also, at one point I felt dirt falling ..."

Reviewed on 5 Oct 2026

Palazzo Mannaioni Suites
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is ąøæ3,677 per night from 1 Nov to 2 Nov
ąøæ3,677
ąøæ4,574 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...
8.4/10 Very good! (1,000 reviews)
"The entrance, the building, the lobby looked very well and promising. Room was small but ok. The shower was terrible, poor mainteined. Room decoration looked agressive. Breakfast was great. Location little far from downtown"

Reviewed on 6 Sept 2026

UNA Hotels Vittoria Firenze
Hotel Firenze 2000

Hotel Firenze 2000

2 out of 5
Viale Raffaello Sanzio, 16 Florence FI
The price is ąøæ5,895 per night from 8 Oct to 9 Oct
ąøæ5,895
ąøæ6,824 total
8 Oct - 9 Oct
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Popular attractions Ponte Vecchio and Piazza del Duomo are located ...
7.2/10 Good! (206 reviews)
"I was very nice and the breakfast was wonderful. The staff was great."

Reviewed on 1 Oct 2026

Hotel Firenze 2000
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at UnitĆ  Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.



Santo Spirito Travel Guide