Santo Spirito Travel Guide
Florence





Visit Santo Spirito
Stay near popular Santo Spirito attractions
Things to do

Reserved Entry Florence Duomo: Express Guided Tour

Florence: Reserved Entrance Ticket to the Medici Chapel

Accademia timed-entry Ticket with App Guide

City Sightseeing Florence Hop-on Hop-off Bus Tour

Florence: Admission Ticket to Franco Zeffirelli Museum

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
Top hotels in Santo Spirito

Hotel Horto Convento
"This hotel was exceptional! The grounds were beautiful. The staff was extremely helpful. The location was perfect. The only downside was they don't have smart TVs and limited stations in English. We have to sleep to TV, but they are getting them soon. Otherwise, I cannot say enough wonderful things ..."
Reviewed on 11 Oct 2026

La Torre Del Cestello

Hostel Santa Monaca

Palazzo Mannaioni Suites
"Staff was vey communicative and helpful. The room was very clean and has everything needed including coffee that is not instant! It is close to everything and would highly recommend."
Reviewed on 10 Oct 2026

UNA Hotels Vittoria Firenze

Hotel Firenze 2000
"Me gusto la ubicación, estamos lo suficientemente cerca de Florencia sin estar en el centro, pero tampoco tan lejos. La habitación no era como en las fotos, a pesar de que la habitación se encontraba muy limpia, los edredones y las sabanas eran viejas, al igual que el TV, aunque todo cumplió su función. ..."
Reviewed on 8 Oct 2026
Where to stay in Santo Spirito

Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.























