Name: Hotel Firenze 2000
Price range: ฿2,850

Stay near popular Santo Spirito attractions

A historic church with a dome and bell tower, surrounded by trees and a fountain in a public square.

Piazza Santo Spirito

9.6/10 (8 reviews)

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.

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Things to do

City Sightseeing Florence Hop-on Hop-off Bus Tour

฿1,103

per adult

74% of travellers recommend

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Reserved Entry Florence Duomo: Express Guided Tour

฿867

per adult

80% of travellers recommend

Accademia timed-entry Ticket with App Guide

฿1,481

per adult

90% of travellers recommend

Florence: Reserved Entrance Ticket to the Medici Chapel

฿675

per adult

Florence: Admission Ticket to Franco Zeffirelli Museum

฿647

per adult

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

฿4,944

per adult

98% of travellers recommend

See all activities in Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Viale Ariosto, 13 Florence FI

฿4,643

฿5,634 total

15 Nov - 16 Nov

includes taxes & fees

Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...

9.8/10 Exceptional! (749 reviews)

"A very nice hotel with great staff members. The front desk staff was extremely helpful and friendly, assisting us with every matter we had. The room was nice and clean, but the bathroom was a little small, but it didn’t affect our stay. The breakfast was good and staff was excellent. One thing I ..."

Reviewed on 28 Oct 2026

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI

฿2,441

฿3,211 total

11 Nov - 12 Nov

includes taxes & fees

Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Piazza del Duomo ...

9/10 Wonderful! (364 reviews)

"Room was terrible, the AC didn't work and it had no windows."

Reviewed on 26 Oct 2026

UNA Hotels Vittoria Firenze

Via Pisana 59 Florence FI

฿2,861

฿3,674 total

5 Nov - 6 Nov

includes taxes & fees

Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...

8.4/10 Very good! (1,002 reviews)

"Conveniently located, easy parking, extremely friendly staff, delicious breakfast, quirky rooms."

Reviewed on 27 Oct 2026

Palazzo Mannaioni Suites

Via Maffia 9 - 17r Florence FI

฿3,059

฿3,894 total

30 Nov - 1 Dec

includes taxes & fees

Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and premium bedding. Our guests praise the helpful staff in their reviews. Popular attractions ...

9.2/10 Wonderful! (1,196 reviews)

"Lovely modern hotel a cross the river, but walking distance to city center. Lots of neighborhood restaurants and bars. Staff was professional and friendly. Note: nearby restaurants and street parties can get very loud some nights when evenings are in"

Reviewed on 28 Oct 2026

Hostel Santa Monaca

Via Santa Monaca 6 Florence FI

฿2,365

฿2,902 total

16 Nov - 17 Nov

includes taxes & fees

Stay at this hostel in Florence. Enjoy free Wi-Fi, daily housekeeping and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza del ...

Hotel Firenze 2000

Viale Raffaello Sanzio, 16 Florence FI

฿2,850

฿3,473 total

29 Nov - 30 Nov

includes taxes & fees

Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Popular attractions Ponte Vecchio and Piazza del Duomo are located ...

See all 535 properties in Santo Spirito

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check Santo Spirito hotel availability

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most. Learn more about Santo Spirito

A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

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A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

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