Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and churches in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the notable monuments in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area.
Things to do
Florence: Reserved Entry Ticket to Bargello Museum
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Florence: Reserved Entrance Ticket to the Medici Chapel
Explore Elegance: Savor 3 Exquisite Wines at Tenuta Bossi
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
Pisa & Lucca with Buccellato tasting from Florence
Top hotels in Santo Spirito
Hotel Horto Convento
The staff were all very friendly! We especially connected with the incredible bartender, Adam. His knowledge of the city helped us to search out hidden gems for food and sight-seeing. The hotel is beautiful, cultural, and stands out as a gem in Florence, tucked away in a quiet area
Reviewed on 13 Dec 2025
Palazzo Mannaioni Suites
The room was clean the day we got in, the next days they didn’t enter to clean it and the rules where to leave clean the kitchen, if not, they would charge 50 euros
Reviewed on 12 Dec 2025
La Torre Del Cestello
Very impressive! We received the notifications few days before arrival to remind us about the date and time. Check-in process was quick and easy, service was great. The staffs were very friendly. Room was large, nice and clean. They kept cleaning daily. Great location and walkable to several attractions ...
Reviewed on 13 Dec 2025
UNA Hotels Vittoria Firenze
Super nice reception staffs, everyone is so friendly and welcoming. But don’t like the red room decoration.
Reviewed on 5 Nov 2025
Oltrarno Splendid
Fabulous place to stay
Reviewed on 7 Dec 2025
Casa Santo Nome di Gesù
I always enjoy my stay here. Nicely located, pleasant breakfast, terrific courtyard, nicely priced.
Reviewed on 11 Nov 2025
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Santo Spirito Basilica while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Via Maggio while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Via de' Calzaiuoli or Giotto's Campanile while you're exploring the neighbourhood.
