Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and churches in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and churches in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the churches in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area.
Things to do
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Florence: Reserved Entrance Ticket to the Medici Chapel
City Sightseeing Florence Hop-on Hop-off Bus Tour
Cinque Terre and Pisa Day Trip with optional Leaning Tower Ticket
Best of Florence Tour with David at Accademia & Duomo (with VIP option)
Top hotels in Santo Spirito
Hotel Horto Convento
"Beautiful building and full of character. Beautifully restored and in a fantastic position."
Reviewed on 29 May 2026
Palazzo Mannaioni Suites
"Lovely, quiet apartment (room 5) with view of the Basilica di Santo Spirito. Clean, well equipped, perfect for a 3-night stay. Very comfortable bed. Hosts very helpful and knowledgeable. Local Trattoria Sant'Agostino well worth a visit for dinner. Would stay here again."
Reviewed on 29 May 2026
La Torre Del Cestello
"Walking distant to everything"
Reviewed on 27 May 2026
Casa Santo Nome di Gesù
"Bdgd"
Reviewed on 24 May 2026
Foresteria Valdese di Firenze - Casa per Ferie
UNA Hotels Vittoria Firenze
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"
Reviewed on 12 May 2026
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Santo Spirito Basilica while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Piazza della Repubblica are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Uffizi Gallery or Via de' Calzaiuoli while you're exploring the neighbourhood.
