Search Hotels in Santo Spirito, Florence

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30 Dec - 31 Dec
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for Santo Spirito hotels

Royal Double Room | Minibar, in-room safe, soundproofing, free WiFi
Oltrarno Splendid

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (98)
"It was a great stay. The renovation style is very tasteful. "
Singapore
Maoying
Oltrarno Splendid
Premium Double Room, Annex Building (in the garden) | Down duvets, in-room safe, individually decorated, desk
AdAstra Suites

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (221)
"Great Room - Lovely breakfast excellent strong Cappuccino and lovely yoghurts. Thanks see you soon. "
United Kingdom
Tim
AdAstra Suites
Classic Suite, 1 King Bed | Premium bedding, down duvets, in-room safe, desk
La Torre Del Cestello

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (231)
"Great location and great rooms"
United States
David
La Torre Del Cestello
Panoramic Triple Room, 1 Bedroom, Air conditioning, City View | Hypo-allergenic bedding, minibar, blackout curtains, soundproofing
SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (24)
"This boutique was an absolute must stay. From the location to the comfort of our room and the lovely staff, it was all you could ask for during a stay in Florence. The walkability was incredible, and even though there is a lively crowd nightly outside of the building, your room is peaceful. Highly recommend this hotel to anyone looking for a unique stay in Florence! "
United States
Chris
SPIRIT OF FLORENCE Boutique Rooms
Lobby
Hotel Horto Convento

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (603)
"Excellent stay"
United States
Renata
Hotel Horto Convento
Interior detail
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1074)
"Perfect stay"
United States
Juan P
Palazzo Mannaioni Suites
Garden
Ottantotto Firenze

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (169)
"Great location and extremely charming!"
United States
Brook
Ottantotto Firenze
Reception
Home in Florence

Home in Florence

Home in Florence
Santo Spirito
9.0 out of 10, Wonderful, (70)
"Perfect place, super friendly owners, really helpful. "
United Kingdom
Paul
Home in Florence
Front of property
Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.4 out of 10, Exceptional, (46)
"Excellent place to stay!"
United States
Diane
Palazzo D'Oltrarno - Residenza D'Epoca
Comfort Double Room, Private Bathroom, Courtyard View | Courtyard view
Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (136)
"Ver clean and quiet, wonderful stay."
United States
kevin
Drom Florence Rooms & Apartments
Apartment | Living area | 24-inch flat-screen TV with digital channels
Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
9.0 out of 10, Wonderful, (2)
"Nice stay. Location was slightly off the beaten track, which we liked. Staff were responsive to us on the phone immediately. Nice flat."
United States
Christopher Pat
Mamo Florence - Bice & Krizia Apartments
Exterior detail
Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
8.8 out of 10, Excellent, (139)
"Our stay was wonderful! Roxy was so welcoming and helpful! The room and view was beautiful as well! Great location with amazing food and sights nearby! "
United States
Jacqueline
Residenza D'Epoca Al Numero 8
Suite | Down duvets, individually decorated, individually furnished
Soggiorno Alessandra

Soggiorno Alessandra

Soggiorno Alessandra
Santo Spirito
8.6 out of 10, Excellent, (86)
"Alessandra is an amazing host, we had a perfect stay! The apartment is in excellent condition and very clean! "
United States
Elias
Soggiorno Alessandra
City Apartment | Private kitchen | Fridge, stovetop, cookware/dishes/utensils
Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (29)
"We stayed here in November and had a wonderful experience. The location worked perfectly for my husband and I, close enough to the center to get everywhere easily, yet set in a quiet residential part of Florence where we could feel the local rhythm of the city. The staff who look after the house were all very easy to communicate with. The whole stay was smooth and comfortable. We truly enjoyed our time here!"
United States
Ray
Appartamenti degli Artisti by Mmega
Superior Apartment | View from room
Bella Vista City View by MMega

Bella Vista City View by MMega

Bella Vista City View by MMega
Santo Spirito
9.6 out of 10, Exceptional, (5)
"The place is very modern and new on the inside. Although very comfortable it had a few minor quirks such as lack of lighting in bathrooms and no place to put anything in one of the showers. Location is fantastic if you like a lot of activity close by. "
United States
Shawn
Bella Vista City View by MMega
22-inch flat-screen TV with digital channels, TV
1900 Artevita

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (177)
"This property is great and the manager is very kind and helpful."
United States
Elizabeth
1900 Artevita
Premium bedding, pillow-top beds, minibar, in-room safe
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze
4.0 star property
Santo Spirito
8.4 out of 10, Very good, (1000)
"Super nice reception staffs, everyone is so friendly and welcoming. But don’t like the red room decoration. "
Canada
Tina
UNA Hotels Vittoria Firenze
Seasonal outdoor pool
Torre di Bellosguardo

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103)
"Beautiful property and wonderful staff."
United States
Brad
Torre di Bellosguardo
Exterior
Santo Spirito Venti

Santo Spirito Venti

Santo Spirito Venti
Santo Spirito
8.8 out of 10, Excellent, (59)
"Great location, friendly staff, I definitely recommend it."
Canada
Pedro
Santo Spirito Venti
Lobby
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (340)
"I always enjoy my stay here. Nicely located, pleasant breakfast, terrific courtyard, nicely priced. "
United States
Marcie
Casa Santo Nome di Gesù
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B

10/10 Excellent
"Very goord place to stay"
Victor 1-night trip
Posted 9 days ago
L'Antica Porta Boutique B&B
Palazzo Oliveto

Palazzo Oliveto

10/10 Excellent
"Great service easy check in Clean safe quiet "
Gabriel 2-night trip
Posted 3 months ago
Palazzo Oliveto

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Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favourite options in the area include AdAstra Suites and SPIRIT OF FLORENCE Boutique Rooms.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 488 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. A few places to visit in the area around Santo Spirito include Piazza di Santa Maria Novella, Piazza del Carmine and Santa Maria della Carmine. When you're sightseeing in Florence, Brancacci Chapel and Il Nabucco di Matteo Gabellini are also worth a stop.