Downtown South San Francisco Travel Guide

San Francisco

An aerial view of a city with a large stadium, several schools, and a dense residential area.
An aerial view of a coastal city with a dense urban area, a large port, and a mountainous backdrop.
A panoramic view of San Francisco's South Peninsula, highlighting the city's dense urban areas, rolling hills, and the iconic Golden Gate Bridge in the distance.

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is ฿4,189 per night from 2 Aug to 3 Aug
฿4,189
฿4,899 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and ...
8.2/10 Very good! (2,032 reviews)
"The check in process was smooth and easy. However the property was ok. The property had plenty of parking with nothing but construction around it yet you had to pay for parking. I felt it was not right to charge for parking as if you were in the building behind the main building you had to drive ..."

Reviewed on 14 Jul 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is ฿4,655 per night from 20 Jul to 21 Jul
฿4,655
฿6,859 total
20 Jul - 21 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,590 reviews)
"Great service. Room clean. Shower was great and the breakfast delish much to choose from. Thank you."

Reviewed on 14 Jul 2026

Hotel Riu Plaza Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
The price is ฿5,188 per night from 11 Aug to 12 Aug
฿5,188
฿6,106 total
11 Aug - 12 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (5,976 reviews)
"Our stay here was everything we hoped for and more. From the moment we arrived, we loved how perfectly located the hotel was in downtown San Francisco. We were able to walk to so many great restaurants, and having the California Street cable car just a short walk away made exploring the city such ..."

Reviewed on 14 Jul 2026

Holiday Inn Golden Gateway by IHG
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
The price is ฿6,664 per night from 17 Jul to 18 Jul
฿6,664
฿9,383 total
17 Jul - 18 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,376 reviews)
"Great stay."

Reviewed on 14 Jul 2026

Hyatt Regency San Francisco
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is ฿6,135 per night from 19 Jul to 20 Jul
฿6,135
฿7,221 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, a fitness centre and valet parking (surcharge). Our guests praise the pool and the helpful ...
8.8/10 Excellent! (3,318 reviews)
"We love this place. We stay often when visiting our daughter. Clean, convenient, heated pool, great staff. We love getting a balcony facing O'Farrell for the hustle and bustle."

Reviewed on 14 Jul 2026

Handlery Union Square Hotel
Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4 out of 5
425 North Point San Francisco CA
The price is ฿5,377 per night from 4 Aug to 5 Aug
฿5,377
฿7,769 total
4 Aug - 5 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful ...
9.2/10 Wonderful! (2,054 reviews)
"It was super clean, the staff was really kind!"

Reviewed on 14 Jul 2026

Hotel Zoe Fisherman's Wharf
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.



Downtown South San Francisco Travel Guide