Search Hotels in Downtown South San Francisco, San Francisco

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.2 out of 10, Very good, (1,972 reviews)
"clean and close to the airport"
United States
William
The price is ฿3,142
฿3,694 total
includes taxes & fees
31 May - 1 Jun
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (1,009 reviews)
"We stayed overnight. The check-in process was quick and easy, and the room was spacious and comfortable. The bathroom was clean and functional, though nothing felt particularly special."
United States
ERIC
The price is ฿3,335
฿3,907 total
includes taxes & fees
9 May - 10 May
Airport Inn

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.2 out of 10, Good, (17 reviews)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is ฿2,146
฿4,946 total
includes taxes & fees
20 May - 21 May
Miller Apartments

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,002 reviews)
"Perfect for quick stays! Clean, safe and affordable! "
United States
carlos
The price is ฿2,589
฿3,052 total
includes taxes & fees
10 May - 11 May
Inn By The SFO

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
16.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (7,468 reviews)
"Great family stay! "
United States
Brian
The price is ฿4,687
฿6,848 total
includes taxes & fees
25 May - 26 May
Hotel Riu Plaza Fisherman's Wharf

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
9.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,986 reviews)
"Very nice stay"
United States
Johnathon
The price is ฿4,094
฿4,654 total
includes taxes & fees
5 Jun - 6 Jun
Hilton San Francisco Airport Bayfront

Grand Bay Hotel San Francisco

Grand Bay Hotel San Francisco
4.0 star property
20.2 km from Downtown South San Francisco
8.4 out of 10, Very good, (1,002 reviews)
"Clean room excellent staff really enjoyed my stay"
United States
Ana Patricia Rivera
The price is ฿3,325
฿5,246 total
includes taxes & fees
29 May - 30 May
Grand Bay Hotel San Francisco

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
20.5 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,433 reviews)
"Overall stay was good "
United States
Ganesh
The price is ฿3,100
฿3,534 total
includes taxes & fees
9 May - 10 May
The Marina Inn on San Francisco Bay

Marina Village Inn

Marina Village Inn
2.0 star property
19.4 km from Downtown South San Francisco
7.4 out of 10, Good, (1,004 reviews)
"Love this spot. Third time staying here. Parking is convenient, staff is friendly & accommodating, rooms are simple cozy & do just the trick for a well rested night! Very much recommend staying here, and the view is so charming! Truly a hidden gem to stay!!!"
United States
Karly N
The price is ฿2,711
฿3,091 total
includes taxes & fees
11 May - 12 May
Marina Village Inn

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
16.6 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (3,819 reviews)
"Great comfortable stay and friendly/helpful staff."
United States
Liliana
The price is ฿4,629
฿7,007 total
includes taxes & fees
25 May - 26 May
Hotel Caza Fisherman's Wharf

The Dylan at SFO

The Dylan at SFO
3.0 star property
7.1 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,870 reviews)
"Great staff and very clean rooms "
United States
Laura
The price is ฿3,809
฿4,525 total
includes taxes & fees
9 May - 10 May
The Dylan at SFO

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG
2.5 star property
20.7 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,005 reviews)
"The friendliness of the staff and the ease of the airport shuttle were two highlights for me. The breakfast provided good too!"
United States
Mary
The price is ฿3,807
฿4,798 total
includes taxes & fees
24 May - 25 May
Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
6.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,264 reviews)
"Clean, modern, close to airport, nice rooms."
Canada
Katherine
The price is ฿4,350
฿5,000 total
includes taxes & fees
31 May - 1 Jun
Aloft San Francisco Airport

Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG
3.5 star property
9 km from Downtown South San Francisco
7.8 out of 10, Good, (2,720 reviews)
"Friendly staff, airport shuttle service a big plus."
United States
MARISSA
The price is ฿3,685
฿4,189 total
includes taxes & fees
10 May - 11 May
Crowne Plaza San Francisco Airport by IHG

LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
13.3 km from Downtown South San Francisco
9.6 out of 10, Exceptional, (2,482 reviews)
"Very nice and clean hotel!"
United States
Ulises
The price is ฿7,379
฿8,684 total
includes taxes & fees
30 May - 31 May
LUMA Hotel San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
16.8 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,553 reviews)
"We had a great stay with clean rooms and friendly staff"
United States
Kara
The price is ฿4,368
฿6,473 total
includes taxes & fees
8 Jun - 9 Jun
Hotel Zephyr San Francisco

Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
1.8 km from Downtown South San Francisco
8.4 out of 10, Very good, (1,793 reviews)
"Great stay"
United States
Jeff
The price is ฿3,297
฿3,888 total
includes taxes & fees
10 May - 11 May
Best Western Plus Grosvenor Airport Hotel

Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown
3.0 star property
13.7 km from Downtown South San Francisco
9.4 out of 10, Exceptional, (2,153 reviews)
"Clean great location great breakfast Beds comfy"
United States
Zorintha Ann
The price is ฿6,432
฿7,570 total
includes taxes & fees
29 May - 30 May
Hyatt Place San Francisco Downtown

Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport
4.0 star property
8.3 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,358 reviews)
"Great location right off the freeway."
United States
Michelle
The price is ฿4,355
฿5,853 total
includes taxes & fees
30 May - 31 May
Hyatt Regency San Francisco Airport

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina
4.0 star property
25.2 km from Downtown South San Francisco
8.2 out of 10, Very good, (4,576 reviews)
"Great price for a clean comfortable stay in Berkeley"
United States
Mary
The price is ฿4,416
฿5,087 total
includes taxes & fees
24 May - 25 May
DoubleTree by Hilton Hotel Berkeley Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

Fisherman's Wharf

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Francisco Airport N is one of the top choices for your stay in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 11 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
South San Francisco Hillside Sign, Sign Hill Park and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed are also worth a visit when you're out sightseeing in South San Francisco.