Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.2 out of 10, Very good, (2,015 reviews)
"Great breakfast and friendly staff"
United States
Joey
The price is ฿3,894
฿4,559 total
includes taxes & fees
29 Jun - 30 Jun
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (1,005 reviews)
"One of my favorite stays in the Bay Area. Highly recommend!"
United States
Megan
The price is ฿3,946
฿4,610 total
includes taxes & fees
2 Jul - 3 Jul
Airport Inn

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,001 reviews)
"awesome"
Canada
Vihaan
Inn By The SFO

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (18 reviews)
"I liked the room"
United States
Lina
The price is ฿2,492
฿5,401 total
includes taxes & fees
25 Jun - 26 Jun
Miller Apartments

La Quinta Inn & Suites by Wyndham Oakland - Hayward

La Quinta Inn & Suites by Wyndham Oakland - Hayward
3.0 star property
26.3 km from Downtown South San Francisco
8.4 out of 10, Very good, (1,261 reviews)
"Great place to stay"
United States
Terry
The price is ฿3,086
฿3,585 total
includes taxes & fees
5 Jul - 6 Jul
La Quinta Inn & Suites by Wyndham Oakland - Hayward

Hotel Shattuck Plaza

Hotel Shattuck Plaza
4.0 star property
27 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,258 reviews)
"Nice room… great location."
United States
Cameron
The price is ฿4,835
฿5,570 total
includes taxes & fees
30 Jun - 1 Jul
Hotel Shattuck Plaza

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG
2.5 star property
20.7 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,005 reviews)
"Nice breakfast. Friendly helpful staff."
United States
Lanniece
The price is ฿3,614
฿4,582 total
includes taxes & fees
10 Jul - 11 Jul
Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
20.5 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,523 reviews)
"Everything was amazing, including the breakfast!!"
United States
Maria
The price is ฿2,515
฿2,867 total
includes taxes & fees
1 Jul - 2 Jul
The Marina Inn on San Francisco Bay

Executive Inn & Suites Embarcadero Cove

Executive Inn & Suites Embarcadero Cove
3.0 star property
20.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,068 reviews)
"Rooms clean,close to airport staff very friendly"
United States
Josephine
The price is ฿3,471
฿4,033 total
includes taxes & fees
30 Jun - 1 Jul
Executive Inn & Suites Embarcadero Cove

Hampton Inn Oakland Downtown-City Center

Hampton Inn Oakland Downtown-City Center
2.5 star property
20.6 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,005 reviews)
"Room was super spacious and clean. Hotel is conveniently located near BART station and the Chinese food options nearby are amazing. I would stay here again for sure!!"
United States
JOSEPHINE
The price is ฿3,757
฿4,365 total
includes taxes & fees
30 Jun - 1 Jul
Hampton Inn Oakland Downtown-City Center

Marina Village Inn

Marina Village Inn
2.0 star property
19.4 km from Downtown South San Francisco
7.6 out of 10, Good, (1,005 reviews)
"The room was clean. It was a nice little stay"
United States
Gabriela
The price is ฿3,956
฿4,510 total
includes taxes & fees
30 Jun - 1 Jul
Marina Village Inn

Hyatt Place Emeryville/San Francisco Bay Area

Hyatt Place Emeryville/San Francisco Bay Area
3.0 star property
22.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,021 reviews)
"Breakfast is good!room is clean!"
United States
Suye
The price is ฿5,310
฿5,957 total
includes taxes & fees
7 Jul - 8 Jul
Hyatt Place Emeryville/San Francisco Bay Area

HYATT house Emeryville/San Francisco Bay Area

HYATT house Emeryville/San Francisco Bay Area
3.0 star property
23 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,345 reviews)
"Great place to stay. Comfortable rooms, spacious bathrooms, helpful staff, cool neighborhood and a yummy breakfast in the morning!"
United States
Barbara
The price is ฿5,311
฿5,958 total
includes taxes & fees
28 Jun - 29 Jun
HYATT house Emeryville/San Francisco Bay Area

Sonesta Emeryville - San Francisco Bay Bridge

Sonesta Emeryville - San Francisco Bay Bridge
3.0 star property
22.6 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,534 reviews)
"A good place to stay"
United States
Thomas
The price is ฿4,285
฿5,177 total
includes taxes & fees
22 Jul - 23 Jul
Sonesta Emeryville - San Francisco Bay Bridge

Hampton Inn & Suites Oakland Airport-Alameda

Hampton Inn & Suites Oakland Airport-Alameda
2.5 star property
17.1 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,007 reviews)
"Great stay"
United States
Shukura
The price is ฿3,844
฿4,390 total
includes taxes & fees
24 Jul - 25 Jul
Hampton Inn & Suites Oakland Airport-Alameda

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina
4.0 star property
25.2 km from Downtown South San Francisco
8.2 out of 10, Very good, (4,798 reviews)
"Great stay in a beautiful setting"
United States
Pauline
The price is ฿3,987
฿4,593 total
includes taxes & fees
7 Jul - 8 Jul
DoubleTree by Hilton Hotel Berkeley Marina

Menlo Park Inn

Menlo Park Inn
3.0 star property
30.2 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,003 reviews)
"Great place!"
United States
Samuel
The price is ฿3,669
฿4,320 total
includes taxes & fees
4 Jul - 5 Jul
Menlo Park Inn

Atherton Park Inn & Suites

Atherton Park Inn & Suites
2.5 star property
27.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,003 reviews)
"Room was clean and the staff very helpful"
Australia
Robert
The price is ฿3,983
฿4,496 total
includes taxes & fees
28 Jun - 29 Jun
Atherton Park Inn & Suites

Good Nite Inn - Redwood City

Good Nite Inn - Redwood City
2.5 star property
23.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,878 reviews)
"it was a really good place to stay!"
United States
Lidiia
The price is ฿3,593
฿4,058 total
includes taxes & fees
28 Jun - 29 Jun
Good Nite Inn - Redwood City

Hotel Griffon

Hotel Griffon
3.5 star property
15.3 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,041 reviews)
"Great location, amazing staff, clean rooms - and affordable."
United States
Justin
The price is ฿3,054
฿4,419 total
includes taxes & fees
5 Jul - 6 Jul
Hotel Griffon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Fisherman's Wharf

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Francisco Airport N is one of the top choices for your stay in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 11 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
South San Francisco Hillside Sign, Sign Hill Park and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed are also worth a visit when you're out sightseeing in South San Francisco.