Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio Zoo Any Day Ticket
฿970
per adult
96% of travellers recommend
San Antonio: Witte Museum Admission Ticket
฿558
per adult
84% of travellers recommend
San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall
฿1,372
per adult
Dining at Hard Rock Cafe San Antonio
฿1,312
per traveller
76% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
฿1,085
per adult
98% of travellers recommend
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is ฿2,955 per night from 20 Sept to 21 Sept
฿2,955
฿3,493 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is ฿2,995 per night from 25 Sept to 26 Sept
฿2,995
฿3,540 total
25 Sept - 26 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,452 reviews)
"WE checked in at 3:pm went to room and it was hot. A.C. temp set at 77 I set the thermostat to 66 (as lowest as it would go) waited 1hr. went to front desk was told it would take 1 hr for room to cool down I told them we had already been in the room for an 1 hr. 30 min. and A.C, setting had not moved ..."
Reviewed on 18 Sept 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is ฿2,965 per night from 25 Sept to 26 Sept
฿2,965
฿3,505 total
25 Sept - 26 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,003 reviews)
"Love staying here because there’s always cops in the parking lot. It makes us feel safe and sleep peacefully. Staff is always really helpful and kind. Only thing is that they do need to upgrade beds. We have been staying here for the past 4 years and we love it."
Reviewed on 18 Sept 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is ฿3,106 per night from 19 Oct to 20 Oct
฿3,106
฿3,690 total
19 Oct - 20 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,165 reviews)
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Reviewed on 16 Sept 2026
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
The price is ฿5,434 per night from 4 Oct to 5 Oct
฿5,434
฿7,375 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (3,087 reviews)
"Beautiful property! Attentive valet and great rooms. AC did it's best with the humidity but it didn't get as cold in the room as I would've liked. I made a request when booking if they could leave a surprise bday note for my daughter in the room and not only did they, but they also made her a beautiful ..."
Reviewed on 18 Sept 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is ฿2,965 per night from 20 Sept to 21 Sept
฿2,965
฿3,505 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very good! (6,463 reviews)
"Valet was awesome! They had the vehicle ready within 5 minutes of notifying them. Hotel was clean and nice and great location."
Reviewed on 18 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Uptown
If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
