
Medical Center District Packages (Flight + Hotel)
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Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District

Downtown San Antonio
4 out of top 10 points of interest in this area
4.5/5(42 area reviews)
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.
Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ฿2,871 per night from 5 Aug to 6 Aug
฿2,871
฿3,393 total
5 Aug - 6 Aug
includes taxes & fees
8.4/10 Very Good! (2,805 reviews)
"I travel to San Antonio weekly to visit my daughter while she is receiving medical treatment . I love it . This is 2nd stay I have 2 more weekends to go and I will be staying here. Just an FYI the parking is no longer free it's $10 which is cheap."
Reviewed on 27 Jul 2025

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ฿2,824 per night from 5 Aug to 6 Aug
฿2,824
฿3,356 total
5 Aug - 6 Aug
includes taxes & fees
8.4/10 Very Good! (1,028 reviews)
"The room was great for the price. Honestly can’t wait for the next time I come back"
Reviewed on 26 Jul 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
7203 Wurzbach Road, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ฿2,980 per night from 8 Aug to 9 Aug
฿2,980
฿3,479 total
8 Aug - 9 Aug
includes taxes & fees
8.8/10 Excellent! (940 reviews)
"Overall this was a great property to stay at. Check in was fast, room clean, bathroom was nice!"
Reviewed on 27 Jul 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns
฿1,168
per adult
92% of travellers recommend

San Antonio: Tower of the Americas Entry Ticket
฿685
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.