Medical Center District Travel Guide

San Antonio

A cityscape with a prominent tower, a large body of water, and a sunset.
A canal with colorful umbrellas and trees along the banks.
A riverside café with colorful umbrellas and tables.
A tranquil waterway flanked by lush greenery and stone pathways.
A canal with a boat, surrounded by lush greenery and a stone bridge.

Stay near popular Medical Center District attractions

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is ฿2,921 per night from 9 Sept to 10 Sept
฿2,921
฿3,452 total
9 Sept - 10 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,635 reviews)
"This place was very good for its facilities, location and very pet friendly."

Reviewed on 8 Sept 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is ฿2,960 per night from 13 Sept to 14 Sept
฿2,960
฿3,499 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites San Antonio Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is ฿2,927 per night from 18 Sept to 19 Sept
฿2,927
฿3,460 total
18 Sept - 19 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Courtyard by Marriott Medical Center San Antonio
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is ฿2,828 per night from 9 Oct to 10 Oct
฿2,828
฿3,360 total
9 Oct - 10 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,165 reviews)
"The room had a really bad smell of cigarette."

Reviewed on 7 Sept 2026

San Antonio Marriott Northwest Medical Center
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is ฿4,819 per night from 13 Sept to 14 Sept
฿4,819
฿6,636 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (3,075 reviews)
"Very nice place . The river walk goes right next to it. It’s a few doors from the loop of the Riverwalk. Great building. Did not hear anyone. Room service was really good after a long day."

Reviewed on 8 Sept 2026

Hotel Valencia Riverwalk
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is ฿2,816 per night from 14 Sept to 15 Sept
฿2,816
฿3,328 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
Riverwalk Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from Alamo to Aztec Theater – discover Downtown San Antonio, a destination also famous for its historic sites.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Quarry Golf Club are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.



Medical Center District Travel Guide