Medical Center District Travel Guide

San Antonio

Photo by Linda Cronan

Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is ฿2,900 per night from 7 Nov to 8 Nov
฿2,900
฿3,427 total
7 Nov - 8 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,011 reviews)
Breakfast is not healthy. The front desk associate forgot to credit my first night to my credit card. They also forgot to offer me the VIP $10 credit.

Reviewed on 25 Oct 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is ฿2,906 per night from 24 Nov to 25 Nov
฿2,906
฿3,454 total
24 Nov - 25 Nov
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free local area shuttle and room service. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,004 reviews)
Staff was friendly. Room was nice and comfortable.

Reviewed on 25 Oct 2025

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ฿2,906 per night from 14 Nov to 15 Nov
฿2,906
฿3,436 total
14 Nov - 15 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,000 reviews)
Over all very quiet peaceful stay

Reviewed on 19 Oct 2025

Courtyard by Marriott Medical Center San Antonio
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
The price is ฿2,874 per night from 16 Nov to 17 Nov
฿2,874
฿3,355 total
16 Nov - 17 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,018 reviews)
Recommend it

Reviewed on 23 Oct 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Crockett Hotel

Crockett Hotel

3 out of 5
320 Bonham, San Antonio, TX
The price is ฿2,776 per night from 27 Nov to 28 Nov
฿2,776
฿3,281 total
27 Nov - 28 Nov
includes taxes & fees
Stay at this 3-star historic hotel in San Antonio. Enjoy free Wi-Fi, valet parking (surcharge) and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,457 reviews)
Great Staff, good customer service, very clean and professional. We are repeat customers of The Crockett.

Reviewed on 24 Oct 2025

Crockett Hotel
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St, San Antonio, TX
The price is ฿4,144 per night from 11 Nov to 12 Nov
฿4,144
฿5,786 total
11 Nov - 12 Nov
includes taxes & fees
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (2,097 reviews)
Hotel Valencia was one of the best hoteles we have stayed at. The staff was fantastic

Reviewed on 27 Oct 2025

Hotel Valencia Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

Tobin Hill might not have many top sights, but Alamo and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
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Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown
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Alamo Heights

You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District Travel Guide