Medical Center District Travel Guide

San Antonio

Photo by Linda Cronan

Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is ฿2,859 per night from 5 Aug to 6 Aug
฿2,859
฿3,380 total
5 Aug - 6 Aug
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,791 reviews)
Would go again
"Staff was excellent! The bed was extremely comfy! Room was nice and cold and very roomy. Continental breakfast was delicious. Only complaint was that the room smelled a little moldy."

Reviewed on 24 Jul 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is ฿2,813 per night from 5 Aug to 6 Aug
฿2,813
฿3,342 total
5 Aug - 6 Aug
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free local area shuttle and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,021 reviews)
Clean, easy, and comfortable
"Check in was quick and efficient. Our room on the first floor was clean and spacious. We bought breakfast with our room reservation. It was fine, but the service was top notch. I'd stay here again should we be back in San Antonio"

Reviewed on 21 Jul 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
The price is ฿2,968 per night from 10 Aug to 11 Aug
฿2,968
฿3,465 total
10 Aug - 11 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (933 reviews)
"It was in a good location where we needed to be and a safe neighborhood"

Reviewed on 25 Jul 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the ...
8/10 Very Good! (5,592 reviews)
"Overall this was a lovely hotel. Parking was an additional fee of 17.00 self park outside public or 40.00 valet per night. The lady who checked us in wss a bit mumbly and not vety polite"

Reviewed on 24 Jul 2025

Riverwalk Plaza
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street, San Antonio, TX
The price is ฿4,129 per night from 8 Aug to 9 Aug
฿4,129
฿4,880 total
8 Aug - 9 Aug
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (3,568 reviews)
"Amazing"

Reviewed on 23 Jul 2025

Drury Plaza Hotel San Antonio Riverwalk
Crockett Hotel

Crockett Hotel

3 out of 5
320 Bonham, San Antonio, TX
The price is ฿3,094 per night from 8 Aug to 9 Aug
฿3,094
฿3,657 total
8 Aug - 9 Aug
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, valet parking (surcharge) and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,432 reviews)
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Reviewed on 21 Jul 2025

Crockett Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

While Northwest Los Angeles Heights may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like San Antonio Zoo and Aquarium and Alamo.

Northwest Los Angeles Heights
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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and Blessed Sacrament Catholic Church.

Shearer Hills - Ridgeview
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

While visiting Tobin Hill, you might make a stop by sights like San Antonio River and Temple Beth-El.

Tobin Hill

Medical Center District Travel Guide