Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio Zoo Any Day Ticket
฿998
per adult
96% of travellers recommend
San Antonio: Witte Museum Admission Ticket
฿574
per adult
86% of travellers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
฿6,039
per adult
100% of travellers recommend
Dining at Hard Rock Cafe San Antonio
฿1,350
per traveller
76% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
฿1,079
per adult
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is ฿2,966 per night from 24 Nov to 25 Nov
฿2,966
฿3,539 total
24 Nov - 25 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,783 reviews)
"Staff was great, but the hotel is in bad shape . Nasty smell and dirty"
Reviewed on 10 Nov 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is ฿2,886 per night from 11 Dec to 12 Dec
฿2,886
฿3,462 total
11 Dec - 12 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,201 reviews)
"Room was not cleaned well. Dust everywhere, bed skirt was frayed. Furniture was worn and scuffed pretty bad. I had to wipe the sink clean when I arrived because it was clearly dirty with makeup. There were dirt and crumbs on the floor, some bits of trash, appeared to not have been vacuumed. The windows ..."
Reviewed on 9 Nov 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is ฿3,021 per night from 15 Nov to 16 Nov
฿3,021
฿3,605 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is ฿2,991 per night from 26 Nov to 27 Nov
฿2,991
฿3,569 total
26 Nov - 27 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,003 reviews)
"Honestly, the location was nice and ducked off and peaceful. It was so quiet, clean and just overall peaceful."
Reviewed on 8 Nov 2026
Hotel Valencia Riverwalk, Valencia Collection
150 E Houston St San Antonio TX
Fully refundable
The price is ฿3,779 per night from 23 Nov to 24 Nov
฿3,779
฿5,469 total
23 Nov - 24 Nov
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is ฿4,296 per night from 15 Nov to 16 Nov
฿4,296
฿5,127 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (5,504 reviews)
"Great location."
Reviewed on 10 Nov 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Uptown Central
If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
