Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Top hotels in Matlacha Isles
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is ฿7,386 per night from 7 Jul to 8 Jul
฿7,386
฿9,890 total
7 Jul - 8 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,243 reviews)
"Great trip! Kids had a great Time!!"
Reviewed on 22 Jun 2026
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ฿2,106 per night from 26 Jun to 27 Jun
฿2,106
฿2,348 total
26 Jun - 27 Jun
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,130 reviews)
"I enjoyed my stay I have no complaints"
Reviewed on 22 Jun 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is ฿5,900 per night from 1 Jul to 2 Jul
฿5,900
฿7,313 total
1 Jul - 2 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
9/10 Wonderful! (1,647 reviews)
"Beautiful oceanfront view."
Reviewed on 22 Jun 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is ฿7,548 per night from 28 Jun to 29 Jun
฿7,548
฿9,240 total
28 Jun - 29 Jun
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,042 reviews)
"Awesome!"
Reviewed on 23 Jun 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is ฿6,829 per night from 12 Jul to 13 Jul
฿6,829
฿8,768 total
12 Jul - 13 Jul
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
The price is ฿9,759 per night from 8 Jul to 9 Jul
฿9,759
฿13,050 total
8 Jul - 9 Jul
includes taxes & fees
Stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools and a full-service spa. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (1,393 reviews)
"From check in to check out this place was a dream. Gorgeous view from balcony of the gulf, rooms were well appointed and the beds were super cozy with upgraded bedding. Robes in the room were an added bonus. From the beach to the pool and back again. Breakfast was free and had wait staff ensuring ..."
Reviewed on 19 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Cape Coral Farmers Market are some notable places to visit nearby.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Lovegrove Gallery & Gardens, some noteworthy sights in the nearby area.
