Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
Southwest Florida Sunset Sail
฿2,300
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
฿2,099
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
฿3,436
per adult
94% of travellers recommend
Historic Walking Tour of Fort Myers
฿986
per adult
100% of travellers recommend
Tiki Pub Amazing Dolphin Eco Adventure
฿1,641
per adult
100% of travellers recommend
Top hotels in Matlacha Isles
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is ฿7,453 per night from 14 Jul to 15 Jul
฿7,453
฿9,979 total
14 Jul - 15 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,273 reviews)
"Amazing place to stay. Not exactly what we had pictured (the pool being on the opposite side of the street with a walking bridge to cross) but still amazing. Valet parking is mandatory, charged per night, make note, it’s not included. Everything was clean, organized… free margarita or nonalcoholic ..."
Reviewed on 30 Jun 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is ฿5,953 per night from 5 Jul to 6 Jul
฿5,953
฿7,380 total
5 Jul - 6 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
9/10 Wonderful! (1,676 reviews)
"En verdad, quise darme un regalo por mi cumpleaños, viajé sola y la verdad la atención, la ayuda, las personas muy atentos y formales lo recomiendo un 100por 100"
Reviewed on 29 Jun 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is ฿8,281 per night from 8 Jul to 9 Jul
฿8,281
฿10,065 total
8 Jul - 9 Jul
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,069 reviews)
"The property is great, from the rooms to the beach it was a great stay"
Reviewed on 29 Jun 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is ฿6,891 per night from 14 Jul to 15 Jul
฿6,891
฿8,848 total
14 Jul - 15 Jul
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,008 reviews)
"The staff was great and the hotel itself is beautiful, with several restaurants located on the property, which made dining very convenient. The sunset from my room was beautiful and definitely the highlight of the stay. My main concern is the pool closing time. The pool closes at “darkish,” (what ..."
Reviewed on 29 Jun 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
The price is ฿3,359 per night from 12 Jul to 13 Jul
฿3,359
฿3,745 total
12 Jul - 13 Jul
includes taxes & fees
Stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,549 reviews)
"Nice staff good location"
Reviewed on 29 Jun 2026
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
The price is ฿2,095 per night from 1 Jul to 2 Jul
฿2,095
฿2,336 total
1 Jul - 2 Jul
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,131 reviews)
"Everything was simple, from check in to getting in the room. I saw quite a few random hairs on the bed but didnt make a fuss or asked for new sheets, I know I could've, I just put a blanket I brought and it was ok. Other than that, room was clean and cold and spacious. Check out was easy, left at ..."
Reviewed on 30 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Glover Bight Trail and Tarpon Point.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Cape Coral Farmers Market are some notable places to visit nearby.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Lovegrove Gallery & Gardens, some noteworthy sights in the nearby area.
