Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
Southwest Florida Sunset Sail
฿2,300
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
฿2,099
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
฿3,436
per adult
94% of travellers recommend
Historic Walking Tour of Fort Myers
฿986
per adult
100% of travellers recommend
Tiki Pub Amazing Dolphin Eco Adventure
฿1,641
per adult
100% of travellers recommend
Top hotels in Matlacha Isles
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is ฿7,480 per night from 13 Jul to 14 Jul
฿7,480
฿10,015 total
13 Jul - 14 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,262 reviews)
"Beautiful and clean as always!"
Reviewed on 27 Jun 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is ฿5,307 per night from 1 Jul to 2 Jul
฿5,307
฿6,662 total
1 Jul - 2 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
9/10 Wonderful! (1,666 reviews)
"The staff were all friendly & helpful. The restaurants have lots to choose from & everything was outstanding!! The beach view was everything I was hoping for!!! The beach sand was fluffy & soft & the guys who handle it take care of making it always look pretty! My only complaint would be they start ..."
Reviewed on 28 Jun 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is ฿7,643 per night from 1 Jul to 2 Jul
฿7,643
฿9,357 total
1 Jul - 2 Jul
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,060 reviews)
"Only thing we were disappointed in was the 7pm pool closing time. For such hot weather, we were very surprised to not have the chance for some evening swimming. Food at the BRGR Lounge was great! We appreciated the blue & white towels for the beach and the ease in switching them out. Thank you, Steve ..."
Reviewed on 26 Jun 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is ฿8,645 per night from 5 Jul to 6 Jul
฿8,645
฿10,807 total
5 Jul - 6 Jul
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,005 reviews)
"As soon as we arrived they helped us with bags and all other necessities! Everyone was very kind and helpful, especially bc I was with my adult special needs daughter,,,,, everyone made out stay very comfortable. Edna, the server by the pool was super nice and helpful ,, we will come back ..."
Reviewed on 27 Jun 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
The price is ฿3,371 per night from 5 Jul to 6 Jul
฿3,371
฿3,759 total
5 Jul - 6 Jul
includes taxes & fees
Stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,545 reviews)
"Great hotel in the heart of Cape Coral!! Mary Jane is amazing!!!! So pleasant and she goes above and beyond to ensure a wonderful stay!"
Reviewed on 28 Jun 2026
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
The price is ฿2,103 per night from 1 Jul to 2 Jul
฿2,103
฿2,345 total
1 Jul - 2 Jul
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,128 reviews)
"I was recommended to stay here and let’s just say never again"
Reviewed on 27 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Glover Bight Trail and Tarpon Point.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Cape Coral Farmers Market are some notable places to visit nearby.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Lovegrove Gallery & Gardens, some noteworthy sights in the nearby area.
