Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
Sunset Cruise Fort Myers Beach
฿1,572
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
฿2,096
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
฿2,296
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
฿3,431
per adult
94% of travellers recommend
Historic Walking Tour of Fort Myers
฿984
per adult
100% of travellers recommend
Top hotels in Matlacha Isles
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is ฿5,916 per night from 15 Sept to 16 Sept
฿5,916
฿8,255 total
15 Sept - 16 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,552 reviews)
"The hotel is beautiful and the staff are very helpful. There are some hidden fees and its a cashless hotel so make sure you are aware of that. Prices of food and drink are fair but for the most part, its a beautiful place. The pool was amazing and the restaurantso we"
Reviewed on 13 Sept 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is ฿4,924 per night from 15 Sept to 16 Sept
฿4,924
฿6,228 total
15 Sept - 16 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
The price is ฿2,198 per night from 20 Sept to 21 Sept
฿2,198
฿2,451 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is ฿5,916 per night from 4 Oct to 5 Oct
฿5,916
฿7,518 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,294 reviews)
"Great place for a relaxed greatway, Food in restaurant was great, everyone was pleasant and willing to andwer any questions We had. We will be back!!"
Reviewed on 14 Sept 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ฿6,319 per night from 28 Sept to 29 Sept
฿6,319
฿8,203 total
28 Sept - 29 Sept
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,004 reviews)
"Very clean resort; nice that beach chairs and umbrella available; good location"
Reviewed on 14 Sept 2026
Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
The price is ฿6,995 per night from 28 Sept to 29 Sept
฿6,995
฿9,974 total
28 Sept - 29 Sept
includes taxes & fees
Stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools and a full-service spa. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (1,455 reviews)
"Great hotel and wonderful staff. Definitely coming back."
Reviewed on 14 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Matlacha Isles hotel availability
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
