Matlacha Isles Travel Guide

Cape Coral


Popular places to visit

Things to do


Top hotels in Matlacha Isles

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
The price is ฿7,851 per night from 16 Jun to 17 Jun
฿7,851
฿9,904 total
16 Jun - 17 Jun
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,014 reviews)
"We had a great experience and would definitely stay here again. Highly recommended for families looking for a relaxing and enjoyable vacation."

Reviewed on 8 Jun 2026

Marriott Sanibel Harbour Resort & Spa
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is ฿6,771 per night from 23 Jun to 24 Jun
฿6,771
฿9,198 total
23 Jun - 24 Jun
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,188 reviews)
"Muy bueno y bonito todo"

Reviewed on 9 Jun 2026

Margaritaville Beach Resort Fort Myers
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
The price is ฿2,300 per night from 21 Jun to 22 Jun
฿2,300
฿2,564 total
21 Jun - 22 Jun
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,126 reviews)
"Un poco acequible"

Reviewed on 8 Jun 2026

Baymont by Wyndham Fort Myers Central
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundable
The price is ฿4,701 per night from 15 Jun to 16 Jun
฿4,701
฿5,974 total
15 Jun - 16 Jun
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
9/10 Wonderful! (1,593 reviews)
"The hotel staff was very nice. The hotel was nice, but there was a huge problem. The first floor of the hotel is occupied by bars, diners, small or bigger eatery places. All they play incredible horrible noisy music. My husband and I had the room with the balcony, but the music was so horribly loud, ..."

Reviewed on 9 Jun 2026

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
The price is ฿8,180 per night from 14 Jun to 15 Jun
฿8,180
฿9,942 total
14 Jun - 15 Jun
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (1,979 reviews)
"The staff were amazing. The restaurant on site was delicious!! Definitely going back!"

Reviewed on 7 Jun 2026

Sanibel Island Beach Resort
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd Fort Myers Beach FL
Stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools and 3 restaurants. Our guests praise the breakfast and the pool in their ...
9.4/10 Exceptional! (1,393 reviews)
"No se los recomiendo muy aburrido mala atención todo súper caro no hay diversión para los niños"

Reviewed on 7 Jun 2026

Pink Shell Beach Resort and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas for the activities you enjoy most.

Pelican

While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

Caloosahatchee

If you're spending some time in Caloosahatchee, Dolphin Marina and Cape Coral Yacht Club Beach are top sights worth seeing.

Yacht Club

While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Cape Coral Farmers Market are some notable places to visit nearby.

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Sun Splash Water Park.

Burnt Store

When in Burnt Store, you can plan a visit to Lovegrove Gallery & Gardens and Burnt Store Marina, some noteworthy sights in the nearby area.



Matlacha Isles Travel Guide