Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
IMAG History & Science Center: Skip-the-Line Ticket
฿672
per adult
Southwest Florida Sunset Sail
฿2,296
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
฿3,431
per adult
94% of travellers recommend
Sunset Dolphin Cruise with Sanibel Lighthouse Views
฿2,020
per adult
94% of travellers recommend
Fort Myers Beach Sunset and Dolphin Watching Cruise
฿2,294
per adult
100% of travellers recommend
Top hotels in Matlacha Isles
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is ฿5,363 per night from 21 Sept to 22 Sept
฿5,363
฿7,650 total
21 Sept - 22 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,561 reviews)
"❤️"
Reviewed on 17 Sept 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is ฿4,481 per night from 21 Sept to 22 Sept
฿4,481
฿5,741 total
21 Sept - 22 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
The price is ฿1,504 per night from 18 Sept to 19 Sept
฿1,504
฿1,677 total
18 Sept - 19 Sept
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is ฿5,959 per night from 4 Oct to 5 Oct
฿5,959
฿7,572 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,303 reviews)
"Room was very clean and stocked, staff was very friendly and helpful with any extras we asked for. Onsite ice machine was a nice bonus, onsite restaurant, cafe, and tiki bar were of great quality. Plenty of nice tourists spots within walking distance including grocery store and off site restaurants. ..."
Reviewed on 17 Sept 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is ฿6,389 per night from 30 Sept to 1 Oct
฿6,389
฿8,293 total
30 Sept - 1 Oct
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
The price is ฿7,046 per night from 28 Sept to 29 Sept
฿7,046
฿10,046 total
28 Sept - 29 Sept
includes taxes & fees
Stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools and a full-service spa. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (1,439 reviews)
"Great place"
Reviewed on 16 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Matlacha Isles hotel availability
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
