Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
Sunset Cruise Fort Myers Beach
฿1,604
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
฿2,139
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
฿2,343
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
฿3,501
per adult
94% of travellers recommend
Historic Walking Tour of Fort Myers
฿1,004
per adult
100% of travellers recommend
Top hotels in Matlacha Isles
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is ฿8,078 per night from 26 Jul to 27 Jul
฿8,078
฿10,190 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,001 reviews)
"Clean hôtel and very good staff"
Reviewed on 22 Jul 2026
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is ฿7,740 per night from 6 Aug to 7 Aug
฿7,740
฿10,326 total
6 Aug - 7 Aug
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is ฿4,837 per night from 28 Jul to 29 Jul
฿4,837
฿6,147 total
28 Jul - 29 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
8.8/10 Excellent! (1,787 reviews)
"Overall, we had a great stay at Lani Kai and would definitely come back! Our room was exactly what we were hoping for, with a king-size bed, two chairs, a refrigerator, a private patio, and an incredible beachfront view. The location is unbeatable—right on the beach and within walking distance of ..."
Reviewed on 22 Jul 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is ฿6,050 per night from 16 Aug to 17 Aug
฿6,050
฿7,688 total
16 Aug - 17 Aug
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,131 reviews)
"Beautiful property and very peaceful Rooms very comfortable and bedding very comfortable. The exterior could use some updating but not a huge deal . I really loved being able to walk out to the beach from the back side of hotel . Pool was great The grounds were very well maintained and had a wonderful ..."
Reviewed on 21 Jul 2026
Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
Stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools and a full-service spa. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (1,408 reviews)
"Everything was excellent"
Reviewed on 22 Jul 2026
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
The price is ฿2,129 per night from 26 Jul to 27 Jul
฿2,129
฿2,374 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,133 reviews)
"I was happy"
Reviewed on 21 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Sun Splash Water Park.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
