An aerial view of a coastal town with a marina, surrounded by water and green land.

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Check prices for these dates

This weekend
4 Sep - 6 Sep
Next weekend
11 Sep - 13 Sep

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Our top choices for Matlacha Isles hotels

A modern dining area with a central island, multiple tables, and chairs.

1. Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
Hancock, 11.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (878 reviews)
"The breakfast buffet was nice and delicious. The staff was very friendly."
United States
Glamaris
The price is ฿3,605
฿4,019 total
includes taxes & fees
21 Sept - 22 Sept
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.

2. Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
1.4 km from Matlacha Isles
9.6 out of 10, Exceptional, (289 reviews)
"Great location very well kept clean will be back soon."
United States
Robby
The price is ฿2,156
฿4,622 total
includes taxes & fees
7 Sept - 8 Sept
Matlacha on Shoreview
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

3. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
Downtown Cape Coral, 13.6 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,648 reviews)
"Great location and breakfast was wonderdul"
United States
Tom
The price is ฿3,362
฿3,748 total
includes taxes & fees
30 Sept - 1 Oct
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
A turquoise building with a red door, surrounded by potted plants and flowers.

4. Angler's Inn

Angler's Inn
2.5 star property
2.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (335 reviews)
"Just a great Air B&B in a small fishing village .perfect stay and we will definitely return."
United States
Paul
The price is ฿5,472
฿6,101 total
includes taxes & fees
3 Sept - 4 Sept
Angler's Inn
A beachside area with colorful beach houses, a dock, and a sandy beach.

5. Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
2.5 km from Matlacha Isles
8.8 out of 10, Excellent, (296 reviews)
"So cute and clean nice dock to sit and relax or fish. Kayaks available to use free as well with life jackets paddles, etc. well equipped rental we can’t wait to go again! Great communication with hosts."
United States
Lori
The price is ฿4,387
฿7,379 total
includes taxes & fees
8 Sept - 9 Sept
Matlacha Tiny Village
A modern hotel lobby with a seating area, a reception desk, and a dining area.

6. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
Caloosahatchee, 12.3 km from Matlacha Isles
8.8 out of 10, Excellent, (1,000 reviews)
"The staff was fantastic and very friendly to work with. Breakfast was wonderful and the hotel room was well kept."
United States
Taylor
The price is ฿3,072
฿3,426 total
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
An outdoor patio with wicker furniture, a fire feature, and string lights.

7. Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
18.9 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,002 reviews)
"Great stay as always! Convenient location, friendly staff, perfectly clean room."
United States
Suzanna
The price is ฿2,915
฿3,251 total
includes taxes & fees
3 Sept - 4 Sept
Hilton Garden Inn Ft Myers
A hotel room with a bed, desk, chair, and a balcony with a view of the sea.

8. Best Western Fort Myers Waterfront

Best Western Fort Myers Waterfront
3.0 star property
Hancock, 16.7 km from Matlacha Isles
7.6 out of 10, Good, (1,003 reviews)
"Amazing location and staff"
United States
Danielle
The price is ฿2,942
฿3,281 total
includes taxes & fees
3 Sept - 4 Sept
Best Western Fort Myers Waterfront
A balcony with a pool view, a table, and chairs.

9. OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
Caloosahatchee, 12.3 km from Matlacha Isles
6.0 out of 10, (1,000 reviews)
"Plenty of parking and staff wad very professional and helpful"
United States
Sarah
The price is ฿1,778
฿1,983 total
includes taxes & fees
8 Sept - 9 Sept
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
A hotel lobby with red sofas, a coffee table, and a reception desk.

10. Holiday Inn Fort Myers - Downtown Area by IHG

Holiday Inn Fort Myers - Downtown Area by IHG
3.0 star property
17.8 km from Matlacha Isles
7.6 out of 10, Good, (1,000 reviews)
"The staff were very helpful and the products were fantastic. The hotel is going under a complete renovation so just be prepared for that but during this time they definitely overcompensate by friendliness and preparation and awareness. The location makes up for the inconvenience."
United States
Kristen
The price is ฿3,283
฿3,661 total
includes taxes & fees
3 Sept - 4 Sept
Holiday Inn Fort Myers - Downtown Area by IHG
A balcony with a table and chairs, large windows, and a view of the sea.

11. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican, 12.3 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice property Clean Staff friendly Love this place"
United States
Zandra
The price is ฿4,256
฿6,231 total
includes taxes & fees
27 Sept - 28 Sept
The Westin Cape Coral Resort At Marina Village
An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

12. Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
20.6 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,183 reviews)
"Always a great place to stay."
United States
heather
The price is ฿3,100
฿3,456 total
includes taxes & fees
6 Sept - 7 Sept
Doubletree by Hilton Fort Myers at Bell Tower Shops
A paved outdoor area with palm trees, string lights, and outdoor seating.

13. Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
29 km from Matlacha Isles
9.6 out of 10, Exceptional, (1,204 reviews)
"Great place to stay."
United States
Brandon
The price is ฿3,648
฿4,067 total
includes taxes & fees
8 Sept - 9 Sept
Holiday Inn Express & Suites Fort Myers Airport by IHG
An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

14. Home2 Suites by Hilton Fort Myers Colonial Blvd

Home2 Suites by Hilton Fort Myers Colonial Blvd
3.0 star property
20.9 km from Matlacha Isles
9.4 out of 10, Exceptional, (816 reviews)
"Staff very attentive. Nice, clean property."
United States
Karon
The price is ฿3,644
฿4,063 total
includes taxes & fees
20 Sept - 21 Sept
Home2 Suites by Hilton Fort Myers Colonial Blvd
A multi-story hotel with a clear sky, palm trees, and a sign reading "HYATT PLACE".

15. Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum
3.0 star property
24.7 km from Matlacha Isles
8.2 out of 10, Very good, (1,008 reviews)
"Helpful staff, clean room and fine breakfast."
United States
Joe
The price is ฿2,454
฿2,736 total
includes taxes & fees
14 Sept - 15 Sept
Hyatt Place Fort Myers/at The Forum
A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

16. Hampton Inn & Suites Fort Myers - Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd
2.5 star property
21 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,000 reviews)
"Hampton Inns are my go to. Always clean, friendly and great breakfast."
United States
Tania
The price is ฿3,780
฿4,214 total
includes taxes & fees
8 Sept - 9 Sept
Hampton Inn & Suites Fort Myers - Colonial Blvd
A hotel with a covered entrance, palm trees, and a well-maintained garden.

17. Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
20.6 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,001 reviews)
"Staff was very friendly- great morning breakfast"
United States
Shelley
The price is ฿3,236
฿3,608 total
includes taxes & fees
8 Sept - 9 Sept
Homewood Suites by Hilton - Fort Myers
A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

18. Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites
2.5 star property
20.8 km from Matlacha Isles
8.8 out of 10, Excellent, (1,223 reviews)
"Good staff, good breakfast."
United States
William
The price is ฿2,179
฿2,430 total
includes taxes & fees
6 Sept - 7 Sept
Best Western Fort Myers Inn & Suites
A modern bar area with a long counter, stools, and a view of the water.

19. Luminary Hotel & Co., Autograph Collection

Luminary Hotel & Co., Autograph Collection
4.0 star property
17.8 km from Matlacha Isles
9.2 out of 10, Wonderful, (546 reviews)
"Excellent place"
United States
Frank Lemay
The price is ฿5,604
฿6,249 total
includes taxes & fees
20 Sept - 21 Sept
Luminary Hotel & Co., Autograph Collection
A hotel reception area with a curved reception desk, potted plants, and a large window with a view.

20. Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
19.3 km from Matlacha Isles
7.6 out of 10, Good, (1,253 reviews)
"Great stay will return"
United States
Brandon
The price is ฿2,221
฿2,476 total
includes taxes & fees
26 Sept - 27 Sept
Americas Best Value Inn Ft. Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Matlacha Isles

Find the best Matlacha Isles areas for the activities you enjoy most.
A pier extending into the water with two gazebos at the end, under a sunset sky.

Pelican

While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

A coastal residential area with a marina, dense greenery, and high-rise buildings in the background.

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

A coastal cityscape with a beach, marina, and dense urban area.

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Sun Splash Water Park.

A sunset over a calm lake with a dock and palm trees.

Yacht Club

While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

A wooden pier extending into calm water with a clear sky and distant land.

Burnt Store

When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.

Top Matlacha Isles Hotel Reviews

DiamondHead Beach Resort

DiamondHead Beach Resort

10/10 Excellent
"Right on the beach, helpful staff, nice and clean. Definitely would stay there again"
Kristina 5-night trip
Posted 3 hours ago
DiamondHead Beach Resort

Frequently asked questions

What is Matlacha Isles like?
Travellers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighbourhood.
How many hotels will I be able to find in the Matlacha Isles area?
When you want to put your feet up after a day of exploring the sights in Cape Coral, you can choose from 17 Expedia hotels and other accommodation options in Matlacha Isles.
If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals in Matlacha Isles.
What are the top things to see and do in Matlacha Isles?
A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens and Cape Royal Golf Club. While you're out sightseeing in Cape Coral, make sure that you visit other sights such as Little Dead Key or Big Dead Key.