An aerial view of a coastal town with a marina, surrounded by water and green land.

Search Hotels in Matlacha Isles, Cape Coral

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Matlacha Isles hotels

A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.

1. Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
1.4 km from Matlacha Isles
9.6 out of 10, Exceptional, (303 reviews)
"The place was perfect for what we needed for this trip."
United States
Francisco
The price is ฿2,015
฿4,494 total
includes taxes & fees
25 Oct - 26 Oct
Matlacha on Shoreview
A modern dining area with a central island, multiple tables, and chairs.

2. Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
Hancock, 11.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (910 reviews)
"The hotel was very clean and breakfast had a lot of variety"
United States
Mauricio
The price is ฿3,825
฿4,265 total
includes taxes & fees
25 Oct - 26 Oct
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

3. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
Downtown Cape Coral, 13.6 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,717 reviews)
"Quiet and clean hotel, very friendly staff, good breakfast!!"
United States
MARYTE
The price is ฿3,394
฿3,785 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
A modern bar area with a long counter, stools, and a view of the water.

4. Luminary Hotel & Co., Autograph Collection

Luminary Hotel & Co., Autograph Collection
4.0 star property
17.8 km from Matlacha Isles
9.2 out of 10, Wonderful, (557 reviews)
"Beautiful property with great amenities around it"
United States
David
The price is ฿6,549
฿7,302 total
includes taxes & fees
1 Nov - 2 Nov
Luminary Hotel & Co., Autograph Collection
A turquoise building with a red door, surrounded by potted plants and flowers.

5. Angler's Inn

Angler's Inn
2.5 star property
2.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (336 reviews)
"I liked the property and location. I also knew what I was getting when I booked the room, as I've stayed here previously, and enjoyed each stay. What I wasn't expecting after the Expedia website showed a 'final price all fees included' was a $60.00 fee added on "by the hotel for the pool, exercise room blah, blah, blah"."
United States
Tim
The price is ฿5,542
฿6,179 total
includes taxes & fees
22 Oct - 23 Oct
Angler's Inn
A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

6. Hampton Inn Fort Myers Downtown

Hampton Inn Fort Myers Downtown
3.0 star property
17.6 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,065 reviews)
"Location, safe, and clean room."
United States
Jason
The price is ฿3,831
฿4,271 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Fort Myers Downtown
A beachside area with colorful beach houses, a dock, and a sandy beach.

7. Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
2.5 km from Matlacha Isles
8.8 out of 10, Excellent, (298 reviews)
"So cute and clean nice dock to sit and relax or fish. Kayaks available to use free as well with life jackets paddles, etc. well equipped rental we can’t wait to go again! Great communication with hosts."
United States
Lori
The price is ฿4,174
฿7,175 total
includes taxes & fees
22 Oct - 23 Oct
Matlacha Tiny Village
A balcony with a table and chairs, large windows, and a view of the sea.

8. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican, 12.3 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,005 reviews)
"Very clean and nice place!"
United States
Charles
The price is ฿4,916
฿6,980 total
includes taxes & fees
15 Nov - 16 Nov
The Westin Cape Coral Resort At Marina Village
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

9. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
17.2 km from Matlacha Isles
8.6 out of 10, Excellent, (1,003 reviews)
"I love everything about this hotel"
United States
Yunior
The price is ฿6,964
฿8,941 total
includes taxes & fees
4 Nov - 5 Nov
Marriott Sanibel Harbour Resort & Spa
A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

10. Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites
2.5 star property
20.8 km from Matlacha Isles
8.8 out of 10, Excellent, (1,200 reviews)
"Good place to stay"
United States
Azael
The price is ฿2,449
฿2,730 total
includes taxes & fees
25 Oct - 26 Oct
Best Western Fort Myers Inn & Suites
An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

11. Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
27.9 km from Matlacha Isles
8.6 out of 10, Excellent, (1,160 reviews)
"The breakfast was amazing"
United States
Erika
The price is ฿2,506
฿2,794 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Inn & Suites Fort Myers Airport
A hotel room with a bed, a desk, a chair, and a small table.

12. SpringHill Suites by Marriott Fort Myers Airport

SpringHill Suites by Marriott Fort Myers Airport
3.0 star property
27.1 km from Matlacha Isles
8.8 out of 10, Excellent, (1,001 reviews)
"Conveniently located to restaurants and grocery"
United States
Ernest
The price is ฿3,825
฿4,265 total
includes taxes & fees
1 Nov - 2 Nov
SpringHill Suites by Marriott Fort Myers Airport
A Holiday Inn Express building with a modern design, featuring a flat facade and a covered entrance area.

13. Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
29 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,208 reviews)
"For $112 a night can't beat it, great location"
United States
Brian
The price is ฿3,359
฿3,745 total
includes taxes & fees
30 Oct - 31 Oct
Holiday Inn Express & Suites Fort Myers Airport by IHG
A large, clear swimming pool with multiple lounge areas and palm trees.

14. Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
23 km from Matlacha Isles
9.0 out of 10, Wonderful, (2,682 reviews)
"Very nice place to stay in for the weekend"
United States
Jose
The price is ฿6,015
฿8,393 total
includes taxes & fees
25 Oct - 26 Oct
Margaritaville Beach Resort Fort Myers
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

15. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
21.7 km from Matlacha Isles
9.6 out of 10, Exceptional, (1,477 reviews)
"It's nice place to stay"
United States
Mario
The price is ฿7,229
฿10,272 total
includes taxes & fees
15 Nov - 16 Nov
Pink Shell Beach Resort and Marina
An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

16. Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
20.6 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,195 reviews)
"Clean, affordable, good location for what we needed, restaurants in walking distance."
United States
James
The price is ฿3,542
฿3,950 total
includes taxes & fees
29 Oct - 30 Oct
Doubletree by Hilton Fort Myers at Bell Tower Shops
A multi-story hotel with a clear sky, palm trees, and a sign reading "HYATT PLACE".

17. Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum
3.0 star property
24.7 km from Matlacha Isles
8.2 out of 10, Very good, (1,009 reviews)
"Fantastic stay! Definitely recommend!"
United States
Daniel
The price is ฿3,056
฿3,408 total
includes taxes & fees
1 Nov - 2 Nov
Hyatt Place Fort Myers/at The Forum
A beach with a variety of seashells and pebbles.

18. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
22.7 km from Matlacha Isles
9.2 out of 10, Wonderful, (2,372 reviews)
"Great place in a great location, very much recommended"
United States
Eldad
The price is ฿6,012
฿7,639 total
includes taxes & fees
22 Oct - 23 Oct
Sanibel Island Beach Resort
A modern kitchen with wooden cabinets, stainless steel appliances, a central island with blue cushioned stools, and a large pendant light.

19. Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
20.6 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,004 reviews)
"Location to every where was perfect"
United States
Jose
The price is ฿3,540
฿3,947 total
includes taxes & fees
27 Oct - 28 Oct
Homewood Suites by Hilton - Fort Myers
An outdoor patio with a round table, chairs, and a grill.

20. Towneplace Suites By Marriott Fort Myers Southeast

Towneplace Suites By Marriott Fort Myers Southeast
3.0 star property
24.4 km from Matlacha Isles
9.4 out of 10, Exceptional, (112 reviews)
"Great place!"
United States
Frantzy
The price is ฿4,400
฿4,906 total
includes taxes & fees
6 Nov - 7 Nov
Towneplace Suites By Marriott Fort Myers Southeast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Matlacha Isles

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.
Matlacha on Shoreview
2.0 star property
9.6
Exceptional
303 reviews
View
A turquoise building with a red door, surrounded by potted plants and flowers.
Angler's Inn
2.5 star property
9.4
Exceptional
336 reviews
View
A modern dining area with a central island, multiple tables, and chairs.
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
9.4
Exceptional
910 reviews
View
A beachside area with colorful beach houses, a dock, and a sandy beach.
Matlacha Tiny Village
3.0 star property
8.8
Excellent
298 reviews
View
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
9.4
Exceptional
1,717 reviews
View

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas for the activities you enjoy most.
A pier extending into the water with two gazebos at the end, under a sunset sky.

Pelican

While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

A coastal residential area with a marina, dense greenery, and high-rise buildings in the background.

Caloosahatchee

If you're spending some time in Caloosahatchee, Dolphin Marina and Cape Coral Yacht Club Beach are top sights worth seeing.

A coastal cityscape with a beach, marina, and dense urban area.

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

A sunset over a calm lake with a dock and palm trees.

Yacht Club

While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

A wooden pier extending into calm water with a clear sky and distant land.

Burnt Store

When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.

Top Matlacha Isles Hotel Reviews

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

8/10 Good
"A nice “retro” hotel with easy access to the beach. The Tiki Bar was straight out of the early sixties - the only tell was the modern music they played. The beach was great, but we were there immediately after a hurricane passed through, so the water was turbid and there was loads of seaweed along the high-water mark. It reminded me of a natural and unassuming shoreline from Florida’s past."
Tim 1-night trip
Posted 7 hours ago
The Lighthouse Resort Inn & Suites

Frequently asked questions

What is Matlacha Isles like?
Travellers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighbourhood.
How many hotels will I be able to find in the Matlacha Isles area?
When you want to put your feet up after a day of exploring the sights in Cape Coral, you can choose from 18 Expedia hotels and other accommodation options in Matlacha Isles.
If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals in Matlacha Isles.
What are the top things to see and do in Matlacha Isles?
A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens and Cape Royal Golf Club. While you're out sightseeing in Cape Coral, make sure that you visit other sights such as Little Dead Key or Big Dead Key.