Downtown South San Francisco Travel Guide
San Francisco
Visit Downtown South San Francisco
Things to do
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
California Academy of Sciences Daytime Admission
San Francisco, Muir Woods, Sausalito and Optional Alcatraz Tour
San Francisco 1 Day Hop-On Hop-Off City Tour
San Francisco Hop-On Hop-Off Tours PLUS Night Tour
Top hotels in Downtown South San Francisco
La Quinta Inn & Suites by Wyndham San Francisco Airport N
"The room was clean, the beds were comfortable, staff was friendly and nice the dining area was clean and suitable for eating. I would definitely recommend staying here and it's close to food eateries I will be staying here again."
Reviewed on 6 Jul 2026
Hotel Riu Plaza Fisherman's Wharf
"The room is clean and breakfast is very good ! Will definitely stay here again if ever we go to SF."
Reviewed on 8 Jul 2026
Handlery Union Square Hotel
"My partner and I initially booked a standard room at the Handlery Hotel San Francisco. On arrival, there was a noticeable odour in the lobby, hallway and our room. We reported this to staff, who promptly sprayed air freshener in both the hallway and room. Our biggest disappointment was that the room ..."
Reviewed on 8 Jul 2026
Hotel Zoe Fisherman's Wharf
"Enjoyed stay though didn’t have chocolate bars for S’mores the only night we were able to enjoy fire pits"
Reviewed on 8 Jul 2026
Hyatt Regency San Francisco
"We loved our room location and appreciated the front desk staff upon checkin. The snack store staff were courteous and generous with information. We did not get to enjoy the bar or breakfast due to time constraints but we like the vibe and ambience of the property. The only thing I did not appreciate ..."
Reviewed on 6 Jul 2026
Holiday Inn Golden Gateway by IHG
"Clean rooms"
Reviewed on 8 Jul 2026
Check Downtown South San Francisco hotel availability
Where to stay in Downtown South San Francisco
Fisherman's Wharf
Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.
Union Square
Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.
Downtown San Francisco
Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.
South of Market
Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.
Nob Hill
Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.
