Midtown Travel Guide

St. Louis

A historic building with a large lawn, a flagpole with flags, and a clear blue sky.
A sundae with chocolate ice cream and whipped cream.
A cathedral interior with Gothic architecture, including pointed arches and ribbed vaults.
A Gothic-style cathedral with intricate stonework, pointed arches, and statues.
A highway with multiple lanes, vehicles, and a bridge overhead.

Stay near popular Midtown attractions

Things to do


Top hotels in Midtown

Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
The price is ฿4,549 per night from 9 Aug to 10 Aug
฿4,549
฿5,319 total
9 Aug - 10 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (790 reviews)
"Only issue was not hot water"

Reviewed on 26 Jul 2026

Element by Marriott St. Louis Midtown
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave St. Louis MO
The price is ฿3,976 per night from 23 Aug to 24 Aug
฿3,976
฿4,728 total
23 Aug - 24 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a 24-hour fitness centre and parking (surcharge). Our guests praise the breakfast and the ...
Residence Inn by Marriott St Louis Downtown
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is ฿5,125 per night from 31 Jul to 1 Aug
฿5,125
฿6,044 total
31 Jul - 1 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,145 reviews)
"Pros: The staff was helpful and kind, location is perfect if planning to attend a St. Louis Cardinals ballgame, there is a Starbucks in building and room was clean. The size of the Junior King Suite is perfect for a family. Cons: The elevators were extremely slow and could not accommodate the large ..."

Reviewed on 26 Jul 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ฿3,289 per night from 9 Aug to 10 Aug
฿3,289
฿3,840 total
9 Aug - 10 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
9/10 Wonderful! (3,290 reviews)
"We came to check in a little early. 3:45. They said the room isn’t available. Ok, we were early. We went to the river cruise and they called us to say the room was ready at 5:25pm!!! Then we made our way back and checked in about 6:15. A couple next to me was curious when their room would be available ..."

Reviewed on 26 Jul 2026

Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is ฿4,380 per night from 2 Aug to 3 Aug
฿4,380
฿5,602 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants and a casino. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (2,212 reviews)
"Haven’t stayed here before and expected a lot more from a casino/hotel. The hotel room has spackle all over the bathroom walls as if it was under construction and there wasn’t a microwave in the room. Also, when gambling most hotel/casinos that we have stayed provide free drinks, but that was not ..."

Reviewed on 26 Jul 2026

Hollywood Casino & Hotel St. Louis
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
The price is ฿3,369 per night from 2 Aug to 3 Aug
฿3,369
฿3,966 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (3,105 reviews)
"Excelente opción sobretodo para la familia con niños pequeños"

Reviewed on 26 Jul 2026

Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Central West End

The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.



Midtown Travel Guide