What is Midtown like?

Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Scott Joplin House State Historic Site as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on our traveller data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool.

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.

What are the top things to see and do in Midtown?

Sights like Scott Joplin House State Historic Site, Red Flag and Museum of Contemporary Religious Art can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium and Gateway Arch. While you're out sightseeing, Hermann Stadium and .ZACK Theater are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.

The Best Hotels in Midtown, St. Louis - 2026 Updated Prices

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Our top choices for Midtown hotels

An outdoor patio area with seating, planters, and a grill.

1. Element by Marriott St. Louis Midtown

Midtown

Corderoa

฿5,160 total

includes taxes & fees

1 Sept - 2 Sept

An outdoor patio area with seating, a fire pit, and a grill.

2. Residence Inn by Marriott St Louis Downtown

Midtown

Jose

฿4,276 total

includes taxes & fees

20 Sept - 21 Sept

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 1.3 km from Midtown

Erik

฿4,871 total

includes taxes & fees

2 Sept - 3 Sept

An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

4. Pear Tree Inn St. Louis Near Union Station

Downtown West, 1.2 km from Midtown

Tanay

฿4,472 total

includes taxes & fees

7 Sept - 8 Sept

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

5. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

0.8 km from Midtown

Tony

฿3,515 total

includes taxes & fees

31 Aug - 1 Sept

A rooftop terrace with wicker furniture, offering a city view.

6. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 3.4 km from Midtown

misty

฿5,848 total

includes taxes & fees

9 Sept - 10 Sept

An indoor pool area with a hot tub, seating, and a stone wall.

7. Drury Plaza Hotel St. Louis Union Station

Downtown West, 1.5 km from Midtown

Jose

฿5,248 total

includes taxes & fees

1 Sept - 2 Sept

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

8. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 3.4 km from Midtown

TRACY

฿5,169 total

includes taxes & fees

29 Aug - 30 Aug

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

9. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 3.1 km from Midtown

Matthew

฿4,750 total

includes taxes & fees

7 Sept - 8 Sept

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

10. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 4.8 km from Midtown

rodnina

฿5,026 total

includes taxes & fees

1 Sept - 2 Sept

A modern outdoor seating area with a fire pit, surrounded by wicker furniture and a landscaped garden.

11. Courtyard by Marriott St. Louis Downtown West

Downtown West, 1.1 km from Midtown

Lisa

฿4,434 total

includes taxes & fees

6 Sept - 7 Sept

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

12. Live by Loews - St.Louis

Downtown St. Louis, 3 km from Midtown

Royce

฿6,181 total

includes taxes & fees

1 Sept - 2 Sept

A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

13. St. Louis Union Station Hotel, Curio Collection by Hilton

Downtown West, 1.7 km from Midtown

Lauren

฿5,674 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor dining area with a table and chairs, a neon sign, and a glass railing overlooking a cityscape.

14. Aloft by Marriott St Louis Central West End

Central West End, 2.2 km from Midtown

Khristina

฿4,353 total

includes taxes & fees

30 Aug - 31 Aug

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

15. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 3 km from Midtown

paullita jeanne

฿5,943 total

includes taxes & fees

30 Aug - 31 Aug

A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.

16. 21C Museum Hotel St Louis

Downtown West, 2.1 km from Midtown

Laura

฿5,654 total

includes taxes & fees

20 Sept - 21 Sept

A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.

17. Courtyard by Marriott St. Louis Downtown/Convention Center

Downtown St. Louis, 2.9 km from Midtown

Caleb

฿4,097 total

includes taxes & fees

6 Sept - 7 Sept

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

18. Hotel Indigo St Louis - Central West End by IHG

Central West End, 3.2 km from Midtown

Simon

฿5,756 total

includes taxes & fees

13 Sept - 14 Sept

A modern kitchen with a hexagonal tile backsplash, built-in appliances, and a central island.

19. Tru By Hilton St. Louis Downtown

Downtown West, 2.5 km from Midtown

isabel

฿3,730 total

includes taxes & fees

7 Sept - 8 Sept

An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

20. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 3.5 km from Midtown

Alexander

฿4,670 total

includes taxes & fees

1 Sept - 2 Sept

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Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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An ornate hall with arched ceilings and intricate patterns.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

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Top Midtown Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent

"Wasn't sure what to expect when we pulled into hotel but looks can be deceiving. Staff was great, check in easy, room was clean, cold, amazing beds, even the shampoo and conditioner were fantastic. After a 16 hour drive it was a welcome and great choice."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"The pool and poolside balcony was very clean and well kept. Even while a bit crowded it seemed welcoming and we really had a nice and relaxing time sitting on the balcony in the evening following a swim and soak in the hot tub. The free breakfast and dinner met more than our expectations. The staff were super friendly and even were greeted with smiling and 'singing' faces early in the morning. Highly recommend!"

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"Staff were friendly and helpful. Room and common areas were clean. We like that our dog was able to stay with us for no extra charge. The only negative thing I'd mention is that the TV in our room kept going in and out. The picture and audio were glitching. Not the end of the world though. We both noted that the mattress and pillows were quite comfortable. I'm definitely going to be staying here while visiting again."

Search Hotels in Midtown, St. Louis

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Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

2. Residence Inn by Marriott St Louis Downtown

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

4. Pear Tree Inn St. Louis Near Union Station

5. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

6. Drury Plaza Hotel St. Louis at the Arch

7. Drury Plaza Hotel St. Louis Union Station

8. Hyatt Regency St. Louis at The Arch

9. Embassy Suites by Hilton St. Louis Downtown

10. Hampton Inn & Suites St. Louis at Forest Park

11. Courtyard by Marriott St. Louis Downtown West

12. Live by Loews - St.Louis

13. St. Louis Union Station Hotel, Curio Collection by Hilton

14. Aloft by Marriott St Louis Central West End

15. Home2 Suites by Hilton St. Louis/Forest Park

16. 21C Museum Hotel St Louis

17. Courtyard by Marriott St. Louis Downtown/Convention Center

18. Hotel Indigo St Louis - Central West End by IHG

19. Tru By Hilton St. Louis Downtown

20. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Where to stay in Midtown

Downtown St. Louis

Clayton

Central West End

Creve Coeur

Downtown West

Top Midtown Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

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