Clayton Travel Guide

St. Louis

Clayton
Photo by Najib Tecle
Photo by kirk allen
Photo by Sarah Mather

Popular places to visit

Things to do


Top hotels in Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ฿2,912 per night from 24 Jan to 25 Jan
฿2,912
฿3,400 total
24 Jan - 25 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,059 reviews)
The room was very cozy and welcoming. The staff was great and friendly from checking in to the breakfast host to checking out.

Reviewed on 5 Jan 2026

Clayton Plaza Hotel & Extended Stay
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave St. Louis MO
The price is ฿3,569 per night from 19 Jan to 20 Jan
฿3,569
฿4,202 total
19 Jan - 20 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the helpful staff in their reviews. ...
8.8/10 Excellent! (925 reviews)
All was fine

Reviewed on 31 Dec 2025

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿4,467 per night from 30 Jan to 31 Jan
฿4,467
฿5,260 total
30 Jan - 31 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
8.8/10 Excellent! (681 reviews)
The gym was amazing!

Reviewed on 21 Dec 2025

Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
The price is ฿15,567 per night from 11 Jan to 12 Jan
฿15,567
฿18,173 total
11 Jan - 12 Jan
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the room service ...
9.2/10 Wonderful! (555 reviews)
Great property. Concierge level wonderful.

Reviewed on 2 Jan 2026

The Ritz-Carlton, St. Louis
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is ฿4,071 per night from 25 Jan to 26 Jan
฿4,071
฿4,752 total
25 Jan - 26 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ...
9/10 Wonderful! (231 reviews)
Staff was amazing

Reviewed on 28 Dec 2025

AC Hotel St. Louis Clayton
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is ฿4,336 per night from 16 Jan to 17 Jan
฿4,336
฿5,114 total
16 Jan - 17 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (4,053 reviews)
Clean, comfortable room. Great location.

Reviewed on 5 Jan 2026

Hyatt Regency St. Louis at The Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Clayton

Default Image

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City
Default Image

Dogtown

When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area.

Dogtown
Default Image

Ladue

Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and St. Louis Art Museum are some interesting sights nearby to check out.

Ladue
Default Image

The Hill

While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby.

The Hill
Default Image

Southwest Garden

While Southwest Garden may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Southwest Garden
Central West End

Central West End

4.5/5(2 area reviews)

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End


Clayton Travel Guide