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Our top choices for Santa Clara hotels

1. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
3.2 km from Santa Clara
9.0 out of 10, Wonderful, (1,001 reviews)
"Very friendly and helpful staff."
United States
Surendrapaul
The price is ฿3,236
฿3,560 total
includes taxes & fees
15 Aug - 16 Aug
Courtyard by Marriott Panama Metromall

2. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 2.8 km from Santa Clara
9.6 out of 10, Exceptional, (730 reviews)
"Excellent hotel conveniently located just 15 min away from Tocumen airport. Not far from downtown. 15 min without traffic. Rooms were nice and beds super comfy. Hotel restaurant was good and staff very professional and friendly. Would definitely stay again."
United States
Carlos
The price is ฿8,914
฿9,805 total
includes taxes & fees
22 Aug - 23 Aug
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

3. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
8.7 km from Santa Clara
8.4 out of 10, Very good, (1,810 reviews)
"excellent choice near the airport with a good price clean pool, good food"
United States
Elizabeth
The price is ฿3,584
฿3,942 total
includes taxes & fees
18 Aug - 19 Aug
Riande Aeropuerto Hotel & Casino

4. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este, 2.8 km from Santa Clara
9.2 out of 10, Wonderful, (346 reviews)
"Excellent location, very professional staff and very clean rooms"
United States
Adolfo
The price is ฿3,763
฿5,891 total
includes taxes & fees
27 Aug - 28 Aug
Corporate Stays Arcadia | Executive Furnished Apartments

5. The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 3 km from Santa Clara
9.0 out of 10, Wonderful, (341 reviews)
"Beautiful decor, spacious rooms, excellent location, good restaurant, the staff very nice."
United States
RAMON
The price is ฿7,374
฿8,111 total
includes taxes & fees
22 Aug - 23 Aug
The Westin Panama

6. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 8 km from Santa Clara
9.0 out of 10, Wonderful, (5,802 reviews)
"Great stay breakfast was amazing will definitely visit again."
United States
Towona
The price is ฿4,567
฿5,024 total
includes taxes & fees
13 Sept - 14 Sept
Hotel Riu Plaza Panama

7. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 6.6 km from Santa Clara
9.6 out of 10, Exceptional, (1,307 reviews)
"Is a great hotel"
United States
Raoel
The price is ฿2,463
฿2,709 total
includes taxes & fees
22 Aug - 23 Aug
Ramada Plaza by Wyndham Panama Punta Pacifica

8. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
10.2 km from Santa Clara
8.6 out of 10, Excellent, (2,671 reviews)
"Good hotel"
United States
Geraldeen
The price is ฿4,171
฿4,807 total
includes taxes & fees
12 Sept - 13 Sept
Crowne Plaza Panama Airport by IHG

9. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco, 6.1 km from Santa Clara
8.8 out of 10, Excellent, (1,000 reviews)
"Overall great hotel, my view was amazing! Close to a few markets . Clean room & helpful staff. Thanks for a great stay."
United States
Sephora
The price is ฿3,933
฿4,326 total
includes taxes & fees
22 Aug - 23 Aug
Aloft by Marriott Panama

10. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 6.1 km from Santa Clara
8.6 out of 10, Excellent, (1,000 reviews)
"Super staff Overall excellent hotel"
United States
Luis
The price is ฿5,661
฿6,227 total
includes taxes & fees
22 Aug - 23 Aug
Sheraton Grand Panama

11. ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
9.7 km from Santa Clara
8.8 out of 10, Excellent, (181 reviews)
"Excellent spot, polite staff, at walking distance from de city."
United States
Juan
The price is ฿3,386
฿4,395 total
includes taxes & fees
16 Aug - 17 Aug
ORHO Hotel Boutique 15 Minutes from PTY Airport

12. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 8.4 km from Santa Clara
9.2 out of 10, Wonderful, (1,213 reviews)
"This is an exceptionally nice hotel, location, service and amenities were all on point."
United States
Geraldeen
The price is ฿2,936
฿3,230 total
includes taxes & fees
13 Sept - 14 Sept
The Executive Hotel

13. Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania, 7.9 km from Santa Clara
9.0 out of 10, Wonderful, (768 reviews)
"The room was well kept, staff was very friendly, helpful and professional."
United States
Romain
The price is ฿3,311
฿3,642 total
includes taxes & fees
18 Aug - 19 Aug
Best Western El Dorado Panama Hotel

14. JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 7.8 km from Santa Clara
9.0 out of 10, Wonderful, (1,001 reviews)
"Hotel was clean and staff was very helpful."
United States
Benjamin A
The price is ฿8,733
฿9,606 total
includes taxes & fees
29 Aug - 30 Aug
JW Marriott Panama

15. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 8.3 km from Santa Clara
9.0 out of 10, Wonderful, (1,069 reviews)
"I loved my stay here. Everything was extremely clean. The staff was amazing. I’d stay again"
United States
Ajsha Lanay
The price is ฿3,476
฿3,824 total
includes taxes & fees
15 Aug - 16 Aug
Waymore Hotel Spa & Casino

16. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 8.4 km from Santa Clara
9.4 out of 10, Exceptional, (2,223 reviews)
"Great breakfast, location excellent, staff friendly and spacious room"
United States
Gilberto
The price is ฿3,798
฿4,178 total
includes taxes & fees
1 Sept - 2 Sept
Plaza Paitilla Inn Hotel

17. Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista, 7.1 km from Santa Clara
9.0 out of 10, Wonderful, (216 reviews)
"This was just an overnight stay, however, staff was super friendly and helpful! Would stay here again!"
United States
Liliana
The price is ฿969
฿1,065 total
includes taxes & fees
15 Aug - 16 Aug
Panama House Bed & Breakfast

18. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
Punta Paitilla, 8 km from Santa Clara
9.0 out of 10, Wonderful, (1,075 reviews)
"Clean room, staff, breakfast"
United States
Christine
The price is ฿5,360
฿5,896 total
includes taxes & fees
16 Aug - 17 Aug
Las Americas Golden Tower Panama

19. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
Punta Paitilla, 8.1 km from Santa Clara
8.6 out of 10, Excellent, (1,712 reviews)
"My husband and i Loved every moment of my stay here will be bk"
United States
angella
The price is ฿3,687
฿4,056 total
includes taxes & fees
4 Sept - 5 Sept
Decapolis Hotel Panama City

20. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 7.8 km from Santa Clara
9.0 out of 10, Wonderful, (2,014 reviews)
"Good location good price"
Canada
Neil Alexander
The price is ฿1,877
฿2,065 total
includes taxes & fees
18 Aug - 19 Aug
Principe Hotel and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Clara

Find the best Santa Clara areas for the activities you enjoy most. Learn more about Santa Clara
Learn more about Santa Clara

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Top Santa Clara Hotel Reviews

Frequently asked questions

What is Santa Clara like?
Travellers will be sure to find plenty to entertain them in Panama City's Santa Clara neighbourhood.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals in Santa Clara.
What are the top things to see and do in Santa Clara?
A few places to visit in the area around Santa Clara include Estadio Rommel Fernandez, Plaza de Francia and Atrio Mall. While you're out sightseeing, Monte Oscuro and Los Pueblos Commercial Center are a couple of additional sights to visit in Panama City.