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4 Sep - 6 Sep
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11 Sep - 13 Sep

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Our top choices for Santa Clara hotels

A buffet with various food items including fruits, juices, and cheeses.

1. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
3.2 km from Santa Clara
9.0 out of 10, Wonderful, (1,019 reviews)
"Great location"
United States
Stephen
The price is ฿3,357
฿3,693 total
includes taxes & fees
5 Sept - 6 Sept
Courtyard by Marriott Panama Metromall
A hotel entrance with a central water feature, seating areas, and potted plants.

2. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 2.8 km from Santa Clara
9.6 out of 10, Exceptional, (744 reviews)
"Great hotel overall"
United States
PAULA
The price is ฿8,687
฿9,556 total
includes taxes & fees
6 Sept - 7 Sept
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A swimming pool with lounge chairs and umbrellas, surrounded by tropical vegetation.

3. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
8.7 km from Santa Clara
8.6 out of 10, Excellent, (1,813 reviews)
"Nice location"
United States
Luis
The price is ฿3,593
฿3,952 total
includes taxes & fees
6 Sept - 7 Sept
Riande Aeropuerto Hotel & Casino
A balcony with wicker chairs and a view of the cityscape.

4. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 6.6 km from Santa Clara
9.6 out of 10, Exceptional, (1,327 reviews)
"excellent breakfast great location"
United States
Maria
The price is ฿3,443
฿3,788 total
includes taxes & fees
8 Sept - 9 Sept
Ramada Plaza by Wyndham Panama Punta Pacifica
A rooftop pool with a city view, lounge chairs, and a clear sky.

5. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este, 2.8 km from Santa Clara
9.2 out of 10, Wonderful, (368 reviews)
"Nice place good location"
United States
Rame
The price is ฿3,651
฿4,235 total
includes taxes & fees
25 Sept - 26 Sept
Corporate Stays Arcadia | Executive Furnished Apartments
A rooftop pool with a city view, modern architecture, and outdoor seating.

6. The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 3 km from Santa Clara
9.0 out of 10, Wonderful, (345 reviews)
"Beautiful decor, spacious rooms, excellent location, good restaurant, the staff very nice."
United States
RAMON
The price is ฿6,822
฿7,504 total
includes taxes & fees
3 Oct - 4 Oct
The Westin Panama
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

7. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 8 km from Santa Clara
9.0 out of 10, Wonderful, (5,911 reviews)
"Great breakfast and beautiful hotel."
United States
Lori
The price is ฿4,080
฿4,487 total
includes taxes & fees
28 Sept - 29 Sept
Hotel Riu Plaza Panama
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.

8. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
10.2 km from Santa Clara
8.6 out of 10, Excellent, (2,702 reviews)
"All was amazing, very convenience location for layover"
United States
RAFAEL
The price is ฿4,315
฿4,965 total
includes taxes & fees
4 Oct - 5 Oct
Crowne Plaza Panama Airport by IHG
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

9. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco, 6.1 km from Santa Clara
8.8 out of 10, Excellent, (1,004 reviews)
"It was a great stay"
United States
Shaniyah
The price is ฿4,391
฿4,830 total
includes taxes & fees
25 Sept - 26 Sept
Aloft by Marriott Panama
A buffet with various food items and a decorative plant.

10. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 6.1 km from Santa Clara
8.6 out of 10, Excellent, (1,002 reviews)
"Clean room, great breakfast"
United States
Rafael
The price is ฿5,825
฿6,407 total
includes taxes & fees
10 Sept - 11 Sept
Sheraton Grand Panama
A hotel named PRINCIPE with a modern facade and large glass windows.

11. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 7.8 km from Santa Clara
9.0 out of 10, Wonderful, (2,037 reviews)
"Good area around for short time visit"
United States
Eliel
The price is ฿1,962
฿2,159 total
includes taxes & fees
14 Sept - 15 Sept
Principe Hotel and Suites
A covered outdoor seating area with a view of a city skyline and water.

12. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 8.4 km from Santa Clara
9.4 out of 10, Exceptional, (2,238 reviews)
"Very centrally located. Breakfast was excellent."
United States
Kenneth
The price is ฿3,427
฿3,770 total
includes taxes & fees
30 Sept - 1 Oct
Plaza Paitilla Inn Hotel
A modern, well-lit buffet area with a variety of food items and neatly arranged plates.

13. Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania, 7.9 km from Santa Clara
9.0 out of 10, Wonderful, (781 reviews)
"The unique i love from this hotel is the entire staff from the Restaurant, Lobby and management are very polite friendly, respectful and make you feel welcome value and special. I rate this hotel ⭐️⭐️⭐️⭐️⭐️"
United States
Marisol
The price is ฿3,319
฿3,651 total
includes taxes & fees
4 Sept - 5 Sept
Best Western El Dorado Panama Hotel
A modern lobby with a chandelier, seating area, reception desk, and a staircase.

14. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 8.4 km from Santa Clara
9.2 out of 10, Wonderful, (1,240 reviews)
"Hotel was very great and highly recommended to visit and stay."
United States
Silvano
The price is ฿2,944
฿3,238 total
includes taxes & fees
30 Sept - 1 Oct
The Executive Hotel
A bedroom with a large bed, a nightstand, a dresser, and decorative wall art.

15. ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
9.7 km from Santa Clara
9.0 out of 10, Wonderful, (191 reviews)
"Excellent spot, polite staff, at walking distance from de city."
United States
Juan
The price is ฿3,394
฿4,406 total
includes taxes & fees
4 Sept - 5 Sept
ORHO Hotel Boutique 15 Minutes from PTY Airport
A rooftop pool with sun loungers and a city skyline in the background.

16. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 8.3 km from Santa Clara
9.0 out of 10, Wonderful, (1,111 reviews)
"This hotel is always a great place to stay"
United States
Amrit
The price is ฿2,680
฿4,774 total
includes taxes & fees
4 Sept - 5 Sept
Waymore Hotel Spa & Casino
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

17. Novotel Panama City

Novotel Panama City
4.0 star property
El Cangrejo, 7.5 km from Santa Clara
9.2 out of 10, Wonderful, (1,271 reviews)
"Great place"
United States
Philip
The price is ฿3,853
฿4,239 total
includes taxes & fees
30 Sept - 1 Oct
Novotel Panama City
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

18. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Campo Alegre, 8.2 km from Santa Clara
9.6 out of 10, Exceptional, (440 reviews)
"Excellent stay"
United States
Al
The price is ฿6,173
฿6,790 total
includes taxes & fees
20 Sept - 21 Sept
Hyatt Regency Panama City
A poolside area with lounge chairs and a view of the ocean.

19. JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 7.8 km from Santa Clara
9.2 out of 10, Wonderful, (1,005 reviews)
"Hotel was clean and staff was very helpful."
United States
Benjamin A
The price is ฿8,494
฿9,344 total
includes taxes & fees
3 Oct - 4 Oct
JW Marriott Panama
A poolside area with covered seating and palm trees.

20. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Obarrio, 7.5 km from Santa Clara
8.8 out of 10, Excellent, (1,005 reviews)
"Great hotel"
United States
Alejandro
The price is ฿6,605
฿7,265 total
includes taxes & fees
7 Sept - 8 Sept
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Clara

Find the best Santa Clara areas for the activities you enjoy most. Learn more about Santa Clara
Learn more about Santa Clara
A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A spiraling skyscraper against a clear blue sky.
Photo by My World
Open Photo by My World

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A bridge over a body of water with several boats.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

Top Santa Clara Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

8/10 Good
"The hotel was constantly crowded"
Karen 1-night trip
Posted 1 hour ago
Hotel Riu Plaza Panama

Frequently asked questions

What is Santa Clara like?
Travellers will be sure to find plenty to entertain them in Panama City's Santa Clara neighbourhood.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals in Santa Clara.
What are the top things to see and do in Santa Clara?
A few places to visit in the area around Santa Clara include Estadio Rommel Fernandez, Plaza de Francia and Atrio Mall. While you're out sightseeing, Monte Oscuro and Los Pueblos Commercial Center are a couple of additional sights to visit in Panama City.