Search Hotels in Santa Clara, Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Clara hotels

Hotel Latino

Hotel Latino
3.0 star property
Calidonia, 9.9 km from Santa Clara
6.6 out of 10, (223 reviews)
"Fair for the price. Restaurant is great"
United States
Gleisther
Hotel Latino

Hotel Pension Corona

Hotel Pension Corona
2.5 star property
Calidonia, 9.9 km from Santa Clara
7.8 out of 10, Good, (114 reviews)
"Great spot for the price "
United States
frank
Hotel Pension Corona

Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 11.5 km from Santa Clara
8.8 out of 10, Excellent, (278 reviews)
"Staff was amazing!! Room was great as well!! "
United States
John
Tantalo Hotel

Hotel Discovery

Hotel Discovery
2.5 star property
Calidonia, 10.1 km from Santa Clara
7.4 out of 10, Good, (173 reviews)
"Rooms was nice and clean. Transportation was easy area was peaceful. "
United States
Roniald
The price is ฿846
฿931 total
includes taxes & fees
23 Jan - 24 Jan
Hotel Discovery

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
19.1 km from Santa Clara
8.0 out of 10, Very good, (1,007 reviews)
"Beautiful property and amazing staff"
United States
CARMEN
The price is ฿7,962
฿8,758 total
includes taxes & fees
19 Feb - 20 Feb
The Westin Playa Bonita Panama

Hotel Acapulco

Hotel Acapulco
3.0 star property
Calidonia, 10.4 km from Santa Clara
7.8 out of 10, Good, (130 reviews)
"Excelente"
United States
Alejandro
The price is ฿971
฿1,068 total
includes taxes & fees
23 Jan - 24 Jan
Hotel Acapulco

Canova

Canova
3.0 star property
Calidonia, 10.4 km from Santa Clara
8.2 out of 10, Very good, (139 reviews)
"All was good! "
United States
Steve
The price is ฿893
฿983 total
includes taxes & fees
18 Feb - 19 Feb
Canova

Residencial & Hotel Palazzo

Residencial & Hotel Palazzo
3.0 star property
Calidonia, 10.3 km from Santa Clara
7.4 out of 10, Good, (122 reviews)
"I recommend this place"
United States
Crystal
Residencial & Hotel Palazzo

Villa Caprichosa

Villa Caprichosa
3.0 star property
28.6 km from Santa Clara
9.8 out of 10, Exceptional, (45 reviews)
"Would definitely visit again "
United States
John
The price is ฿7,756
฿8,532 total
includes taxes & fees
25 Jan - 26 Jan
Villa Caprichosa

Hotel Vía España

Hotel Vía España
3.0 star property
Calidonia, 9.4 km from Santa Clara
6.2 out of 10, (174 reviews)
"Don’t stay there it’s the "
United States
Andreas
Hotel Vía España

Magnolia Inn

Magnolia Inn
2.0 star property
San Felipe, 11.6 km from Santa Clara
8.8 out of 10, Excellent, (430 reviews)
"Location location location. Also, the common area and kitchen were very nice. We really appreciated the staffs willingness to store our bags prior to check in. "
United States
James
The price is ฿2,742
฿3,017 total
includes taxes & fees
2 Feb - 3 Feb
Magnolia Inn

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista, 7.1 km from Santa Clara
9.0 out of 10, Wonderful, (189 reviews)
"It was a great stay in a great neighborhood with many food and beverage options, fantastic hosts and an interesting mix of people "
Canada
Brad
The price is ฿1,282
฿1,410 total
includes taxes & fees
4 Feb - 5 Feb
Panama House Bed & Breakfast

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
25.7 km from Santa Clara
7.8 out of 10, Good, (685 reviews)
"Beautiful rooms and grounds. Love ❤️ the nature around the resort."
United States
John
The price is ฿4,719
฿5,191 total
includes taxes & fees
23 Jan - 24 Jan
Gamboa Rainforest Reserve

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
8.7 km from Santa Clara
8.6 out of 10, Excellent, (1,845 reviews)
"Clean room and friendly staff. Breakfast was very good also. "
United States
Ramon
The price is ฿3,880
฿4,268 total
includes taxes & fees
22 Feb - 23 Feb
Riande Aeropuerto Hotel & Casino

Holiday Inn Panama Canal by IHG

Holiday Inn Panama Canal by IHG
3.5 star property
12.6 km from Santa Clara
8.6 out of 10, Excellent, (450 reviews)
"The staff was so cordial and nice "
United States
Sonny
The price is ฿3,350
฿3,685 total
includes taxes & fees
18 Feb - 19 Feb
Holiday Inn Panama Canal by IHG

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 2.8 km from Santa Clara
9.2 out of 10, Wonderful, (199 reviews)
"Really loved this place"
United States
Alejandra
The price is ฿2,648
฿5,675 total
includes taxes & fees
25 Jan - 26 Jan
Arcadia Condo Suites

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
San Felipe, 11.6 km from Santa Clara
9.8 out of 10, Exceptional, (265 reviews)
"Great location!"
United States
Erik
The price is ฿11,082
฿12,191 total
includes taxes & fees
17 Feb - 18 Feb
Hotel La Compañía Casco Antiguo

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
10.2 km from Santa Clara
8.6 out of 10, Excellent, (2,384 reviews)
"Clean, welcoming staff, close to airport for travel "
Canada
Lynn
The price is ฿3,444
฿3,788 total
includes taxes & fees
9 Feb - 10 Feb
Crowne Plaza Panama Airport by IHG

Hotel Costa Inn

Hotel Costa Inn
3.0 star property
Calidonia, 9.7 km from Santa Clara
7.0 out of 10, Good, (554 reviews)
"Nice bathroom "
United States
Derrick
Hotel Costa Inn

Hotel Caribe

Hotel Caribe
3.0 star property
Calidonia, 10.6 km from Santa Clara
7.6 out of 10, Good, (290 reviews)
"The problem was when I arrived they did not honor my reservation. They informed me that the people before me had a problem with their tour bus breaking down. Therefore they offered to send me to some flea bag hotel for the night. Outside the front door you can smell the open sewer. It’s a good price! "
United States
Kenneth
The price is ฿1,485
฿1,634 total
includes taxes & fees
2 Feb - 3 Feb
Hotel Caribe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Clara

Find the best Santa Clara areas for the activities you enjoy most. Learn more about Santa Clara
Learn more about Santa Clara

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or Museum of History Panama while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

While visiting San Felipe, you might make a stop by sights like Interoceanic Canal Museum and Museum of History Panama.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Top Santa Clara Hotel Reviews

Frequently asked questions

What is Santa Clara like?
Travellers will be sure to find plenty to entertain them in Panama City's Santa Clara neighbourhood.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals in Santa Clara.
What are the top things to see and do in Santa Clara?
A few places to visit in the area around Santa Clara include Estadio Rommel Fernandez, Plaza de Francia and Atrio Mall. While you're out sightseeing, Monte Oscuro and Los Pueblos Commercial Center are a couple of additional sights to visit in Panama City.