Santa Ana Travel Guide

Antigua Guatemala

Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.

Popular places to visit

Things to do


Top hotels in Santa Ana

Casa Buho B&B

Casa Buho B&B

3 out of 5
77 Calle del Agua Antigua Guatemala Guatemala
The price is ฿1,658 per night from 4 Jun to 5 Jun
฿1,658
฿2,023 total
4 Jun - 5 Jun
includes taxes & fees
Stay at this hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and daily housekeeping. Popular attractions Casa Santo Domingo Museum and Central Park ...
Casa Buho B&B
Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is ฿3,736 per night from 21 Jun to 22 Jun
฿3,736
฿4,559 total
21 Jun - 22 Jun
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
9.2/10 Wonderful! (3,315 reviews)
"Breakfast, pool, clean"

Reviewed on 21 May 2026

Barceló Guatemala City
Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center

4.5 out of 5
Calzada Roosevelt 22-43 Guatemala City Guatemala
The price is ฿3,688 per night from 19 Jun to 20 Jun
฿3,688
฿4,499 total
19 Jun - 20 Jun
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
9.2/10 Wonderful! (1,000 reviews)
"Great personable friendly staff, great location with malls and restaurants connected to the hotel, have stayed here many times and love the safe location."

Reviewed on 19 May 2026

Tikal Futura Hotel & Convention Center
Clarion Suites Guatemala City

Clarion Suites Guatemala City

4 out of 5
14 Street 3-08 Zona 10 Guatemala City Guatemala
The price is ฿3,321 per night from 23 May to 24 May
฿3,321
฿4,052 total
23 May - 24 May
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,018 reviews)
"The cleanliness was an issue!"

Reviewed on 19 May 2026

Clarion Suites Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is ฿7,767 per night from 21 Jun to 22 Jun
฿7,767
฿9,873 total
21 Jun - 22 Jun
includes taxes & fees
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,059 reviews)
"Beds were super comfortable"

Reviewed on 20 May 2026

Hotel Museo Spa Casa Santo Domingo
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is ฿6,187 per night from 31 May to 1 Jun
฿6,187
฿8,362 total
31 May - 1 Jun
includes taxes & fees
Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
9.6/10 Exceptional! (1,001 reviews)
"Highly recommended"

Reviewed on 21 May 2026

Hotel Camino Real Antigua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Barrio de La Concepción
The Santa Catalina arch and the main street of Antigua city at sunrise, Guatemala.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Historic Center


Santa Ana Travel Guide