Santa Ana Travel Guide
Antigua Guatemala
Visit Santa Ana
Things to do
From Antigua: Pacaya Volcano Tour in English/Spanish
฿754
per adult
88% of travellers recommend
From Antigua: Adventure, 2-Day Hiking to Acatenango Volcano
฿1,869
per adult
From Antigua: Pacaya Volcano Trek
฿787
per adult
90% of travellers recommend
Antigua: ATV Guided Sunset Tour
฿2,132
per adult
100% of travellers recommend
Top hotels in Santa Ana
Barceló Guatemala City
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is ฿3,171 per night from 27 Sept to 28 Sept
฿3,171
฿3,868 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
Hotel Museo Spa Casa Santo Domingo
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is ฿7,930 per night from 23 Sept to 24 Sept
฿7,930
฿10,081 total
23 Sept - 24 Sept
includes taxes & fees
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
9.4/10 Exceptional! (1,158 reviews)
"This was my first time staying at Casa Santo Domingo, and it was truly an exceptional experience. The hotel is spectacular and completely unique — its history, architecture, gardens, art, and atmosphere make staying here an experience in itself. The staff was outstanding throughout our stay: warm, ..."
Reviewed on 20 Sept 2026
Wyndham Garden Guatemala City
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is ฿3,654 per night from 3 Oct to 4 Oct
฿3,654
฿4,457 total
3 Oct - 4 Oct
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
Hotel Camino Real Antigua
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is ฿6,297 per night from 22 Sept to 23 Sept
฿6,297
฿8,516 total
22 Sept - 23 Sept
includes taxes & fees
Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
Adriatika Hotel & Residence
4 av 20-44 Zona 14 Guatemala City Guatemala
The price is ฿3,898 per night from 10 Oct to 11 Oct
฿3,898
฿4,755 total
10 Oct - 11 Oct
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
Tikal Futura Hotel & Convention Center
Calzada Roosevelt 22-43 Guatemala City Guatemala
The price is ฿3,812 per night from 4 Oct to 5 Oct
฿3,812
฿4,650 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
9.2/10 Wonderful! (1,002 reviews)
"Tikal Futura has a great location, near Miraflores mall, with a good restaurant on site, and helpful, professional staff. Some rooms have a wonderful view, some can be a bit noisy, but overall, it's my favorite hotel in Guatemala City. It is showing a bit of age, as the flooring in some rooms is ..."
Reviewed on 19 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Ana
Find the best Santa Ana areas for the activities you enjoy most.
Historic Center
If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.
Barrio de La Concepción
While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.
