Santa Ana Travel Guide

Antigua Guatemala

Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.

Popular places to visit

Antigua, Guatemala

Antigua Guatemala Cathedral

After visiting Antigua Guatemala Cathedral, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's volcano viewpoints or seek out its local tours.

Antigua Guatemala Cathedral
Antigua, Guatemala, volcano

Central Park

Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops or seek out its local tours.

Central Park
The Santa Catalina arch and the main street of Antigua city at sunrise, Guatemala.

Santa Catalina Arch

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this family-friendly area.

Santa Catalina Arch
Traditional vase and jar at market in Antigua, Guatemala.

Antigua Market

During your trip to Antigua Guatemala, you can enjoy retail therapy at Antigua Market. Discover the volcano viewpoints in this romantic area or enjoy its local tours.

Antigua Market
La Merced Church

La Merced Church

After visiting La Merced Church, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops or seek out its local tours.

La Merced Church
Cerro de la Cruz Antigua Guatemala

Cerro de La Cruz

You can find out about the history of Antigua Guatemala with a trip to Cerro de La Cruz. Discover the area's volcano viewpoints or seek out its local tours.

Cerro de La Cruz

Things to do

Antigua: ATV Guided Sunset Tour

Antigua: ATV Guided Sunset Tour

฿2,075
per adult
100% of travellers recommend
Antigua: ATV Guided Sunset Tour
Picture 5 for Activity From Antigua: Pacaya Volcano Trek

From Antigua: Pacaya Volcano Trek

฿766
per adult
90% of travellers recommend
From Antigua: Pacaya Volcano Trek
Lake Atitlan One Day Tour from Antigua

Lake Atitlan One Day Tour from Antigua

฿2,938
per adult
86% of travellers recommend
Lake Atitlan One Day Tour from Antigua
From Antigua: Pacaya Volcano Tour in English/Spanish

From Antigua: Pacaya Volcano Tour in English/Spanish

฿734
per adult
80% of travellers recommend
From Antigua: Pacaya Volcano Tour in English/Spanish
Chicken Bus Experiencie, let ́s go to San Juan del Obispo

Chicken Bus Experiencie, let ́s go to San Juan del Obispo

฿798
per adult
Chicken Bus Experiencie, let ́s go to San Juan del Obispo
Hobbitenango & Antigua Shared Day Tour

Hobbitenango & Antigua Shared Day Tour

฿3,161
per adult
Hobbitenango & Antigua Shared Day Tour
See all activities in Antigua Guatemala

Top hotels in Santa Ana

Casa Buho B&B

Casa Buho B&B

3 out of 5
77 Calle del Agua Antigua Guatemala Guatemala
The price is ฿1,658 per night from 4 Jun to 5 Jun
฿1,658
per night
4 Jun - 5 Jun
Stay at this hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and daily housekeeping. Popular attractions Casa Santo Domingo Museum and Central Park ...
Casa Buho B&B
Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is ฿3,487 per night from 16 Jun to 17 Jun
฿3,487
per night
16 Jun - 17 Jun
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
9.2/10 Wonderful! (3,313 reviews)
"Barceló was beautiful. Staff was wonderful and the beds were very comfortable. A lot of restaurant options and gift shops to purchase souvenirs."

Reviewed on 19 May 2026

Barceló Guatemala City
Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center

4.5 out of 5
Calzada Roosevelt 22-43 Guatemala City Guatemala
The price is ฿3,688 per night from 19 Jun to 20 Jun
฿3,688
per night
19 Jun - 20 Jun
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
9.2/10 Wonderful! (1,000 reviews)
"Great personable friendly staff, great location with malls and restaurants connected to the hotel, have stayed here many times and love the safe location."

Reviewed on 19 May 2026

Tikal Futura Hotel & Convention Center
Clarion Suites Guatemala City

Clarion Suites Guatemala City

4 out of 5
14 Street 3-08 Zona 10 Guatemala City Guatemala
The price is ฿3,321 per night from 23 May to 24 May
฿3,321
per night
23 May - 24 May
Stay at this business-friendly hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,018 reviews)
"The cleanliness was an issue!"

Reviewed on 19 May 2026

Clarion Suites Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is ฿7,767 per night from 21 Jun to 22 Jun
฿7,767
per night
21 Jun - 22 Jun
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,059 reviews)
"Beds were super comfortable"

Reviewed on 20 May 2026

Hotel Museo Spa Casa Santo Domingo
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is ฿6,187 per night from 31 May to 1 Jun
฿6,187
per night
31 May - 1 Jun
Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
9.6/10 Exceptional! (1,001 reviews)
"Highly recommended"

Reviewed on 21 May 2026

Hotel Camino Real Antigua
See all 1,243 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Barrio de La Concepción
The Santa Catalina arch and the main street of Antigua city at sunrise, Guatemala.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Historic Center

Santa Ana Travel Guide