Search Hotels in Santa Ana, Antigua Guatemala

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Our top choices for Santa Ana hotels

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (25 reviews)
"This place has two parts, the hotel and a hostel, I stayed in the private room of the hostel part, it wasn’t very good, but the whole place is very nice, like an oasis with a lot of plants, the hotel Part would be very nice."
United States
SUSAN
The price is ฿1,242
฿1,515 total
includes taxes & fees
21 Jun - 22 Jun
Hostal Casa Buho

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (52 reviews)
"Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning"
United States
Patrick
The price is ฿1,500
฿1,829 total
includes taxes & fees
8 Jun - 9 Jun
Casa Buho B&B

La guarida del caudillo

La guarida del caudillo
1.0 star property
Santa Ana
The price is ฿889
฿1,084 total
includes taxes & fees
5 Jun - 6 Jun
La guarida del caudillo

Castillo De Los Gigantes

Castillo De Los Gigantes
2.0 star property
Santa Ana
6.0 out of 10, (1 review)
"This property should be listed on Airbnb, it is not a hostel/hotel, it's more like a spare room in someone's home. There's nothing nearby. It was a saviour during semana santa, but otherwise not a particularly good place to stay. That being said the people were lovely, and the room was decent for the price."
American Samoa
Ella
The price is ฿434
฿929 total
includes taxes & fees
5 Jun - 6 Jun
Castillo De Los Gigantes

Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center
4.5 star property
20.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,017 reviews)
"Great food, rooms are clean!!"
United States
Rossana
The price is ฿3,691
฿4,503 total
includes taxes & fees
7 Jun - 8 Jun
Tikal Futura Hotel & Convention Center

Le Suisse Spa

Le Suisse Spa
3.0 star property
6.8 km from Santa Ana
8.6 out of 10, Excellent, (31 reviews)
"I 100% recommend Le Suisse Spa. The facilities are first-class, the room was super clean, and the service was excellent. The staff made us feel very comfortable. We will definitely be coming back soon."
United States
David
The price is ฿3,290
฿4,014 total
includes taxes & fees
5 Jun - 6 Jun
Le Suisse Spa

Mestizo Cortijo

Mestizo Cortijo
3.0 star property
4.3 km from Santa Ana
8.8 out of 10, Excellent, (134 reviews)
"Beautiful property, spacious rooms, great views, amazing breakfast, friendly staff"
United States
Ligia
The price is ฿3,935
฿4,801 total
includes taxes & fees
5 Jul - 6 Jul
Mestizo Cortijo

Casa Aurora

Casa Aurora
3.0 star property
20.9 km from Santa Ana
8.8 out of 10, Excellent, (201 reviews)
"It was a really nice place enjoyed staying"
United States
Santos
The price is ฿1,800
฿2,197 total
includes taxes & fees
7 Jun - 8 Jun
Casa Aurora

L Aurora Inn

L Aurora Inn
3.0 star property
21 km from Santa Ana
9.0 out of 10, Wonderful, (151 reviews)
"The best hotel!"
United States
Krisia
The price is ฿1,932
฿2,956 total
includes taxes & fees
22 Jun - 23 Jun
L Aurora Inn

Mariana's Petit Hotel

Mariana's Petit Hotel
3.0 star property
20.9 km from Santa Ana
9.2 out of 10, Wonderful, (194 reviews)
"Great owner"
United States
kurt
The price is ฿1,474
฿1,799 total
includes taxes & fees
12 Jun - 13 Jun
Mariana's Petit Hotel

Kawilal Hotel

Kawilal Hotel
3.5 star property
13.9 km from Santa Ana
9.0 out of 10, Wonderful, (144 reviews)
"Great place to spend some family vacations. Good staff, really good breakfast option. The food (lunch and dinner) a little bit expensive."
United States
David
The price is ฿4,417
฿5,389 total
includes taxes & fees
16 Jun - 17 Jun
Kawilal Hotel

Hilton Guatemala City

Hilton Guatemala City
4.5 star property
25.9 km from Santa Ana
8.6 out of 10, Excellent, (721 reviews)
"The property is beautiful and unique. I really felt at home so beautiful and comfortable."
United States
Olga
The price is ฿3,092
฿3,773 total
includes taxes & fees
15 Jun - 16 Jun
Hilton Guatemala City

Barceló Guatemala City

Barceló Guatemala City
4.5 star property
22.7 km from Santa Ana
9.2 out of 10, Wonderful, (3,331 reviews)
"Nice hotel and it is really close to the airport."
United States
Anonymous traveller
The price is ฿3,594
฿4,385 total
includes taxes & fees
5 Jul - 6 Jul
Barceló Guatemala City

Ole España

Ole España
2.5 star property
20.8 km from Santa Ana
9.4 out of 10, Exceptional, (33 reviews)
"I liked the breakfast and clean area"
United States
Juan
The price is ฿1,186
฿1,447 total
includes taxes & fees
7 Jun - 8 Jun
Ole España

In & Out Hotel

In & Out Hotel
3.0 star property
20.9 km from Santa Ana
8.6 out of 10, Excellent, (871 reviews)
"We love staying atbthe In and Out, rooms have AC, very clean, great breakfast and a very reasonable price."
United States
Julian
The price is ฿1,627
฿1,985 total
includes taxes & fees
7 Jun - 8 Jun
In & Out Hotel

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
26.4 km from Santa Ana
8.6 out of 10, Excellent, (1,001 reviews)
"Best Hotel in Guatemala City! The food was very delicious and rooms are very clean."
United States
Manuel
The price is ฿4,787
฿5,840 total
includes taxes & fees
4 Jul - 5 Jul
AC Hotel by Marriott Guatemala City

Villas Santander

Villas Santander
3.0 star property
24.7 km from Santa Ana
7.4 out of 10, Good, (251 reviews)
"Parking is easy "
United States
Walter
The price is ฿1,018
฿1,242 total
includes taxes & fees
16 Jun - 17 Jun
Villas Santander

Casa Carmel Bed and Breakfast

Casa Carmel Bed and Breakfast
3.0 star property
24.2 km from Santa Ana
9.6 out of 10, Exceptional, (133 reviews)
"Loved the breakfast! Great period house built in the 1930s, located in the historic district."
United States
Sudhir
The price is ฿1,951
฿2,380 total
includes taxes & fees
26 Jun - 27 Jun
Casa Carmel Bed and Breakfast

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
23.9 km from Santa Ana
9.4 out of 10, Exceptional, (347 reviews)
"Super convenient hotel near the airport and some restaurants. Very comfortable beds and really nice staff."
United States
penelope
The price is ฿3,456
฿4,216 total
includes taxes & fees
11 Jun - 12 Jun
Good Hotel Guatemala City

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.8 out of 10, Excellent, (273 reviews)
"Great place"
United States
CHRISTOPHER
The price is ฿3,659
฿4,464 total
includes taxes & fees
13 Jun - 14 Jun
Hotel Vista Quince
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favourite place to stay in Santa Ana?
Based on our traveller data, Casa Buho B&B is one of the top choices for your stay in Santa Ana. This hotel offers a restaurant and free parking.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 14 hotels and other accommodation options in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.