Search Hotels in Santa Ana, Antigua Guatemala

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Our top choices for Santa Ana hotels

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (25 reviews)
"This place has two parts, the hotel and a hostel, I stayed in the private room of the hostel part, it wasn’t very good, but the whole place is very nice, like an oasis with a lot of plants, the hotel Part would be very nice."
United States
SUSAN
The price is ฿1,234
฿1,505 total
includes taxes & fees
15 Jun - 16 Jun
Hostal Casa Buho

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (52 reviews)
"Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning"
United States
Patrick
The price is ฿1,490
฿1,817 total
includes taxes & fees
2 Jun - 3 Jun
Casa Buho B&B

Castillo De Los Gigantes

Castillo De Los Gigantes
2.0 star property
Santa Ana
6.0 out of 10, (1 review)
"This property should be listed on Airbnb, it is not a hostel/hotel, it's more like a spare room in someone's home. There's nothing nearby. It was a saviour during semana santa, but otherwise not a particularly good place to stay. That being said the people were lovely, and the room was decent for the price."
American Samoa
Ella
The price is ฿431
฿923 total
includes taxes & fees
8 Jun - 9 Jun
Castillo De Los Gigantes

La guarida del caudillo

La guarida del caudillo
1.0 star property
Santa Ana
The price is ฿902
฿1,101 total
includes taxes & fees
8 Jun - 9 Jun
La guarida del caudillo

Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center
4.5 star property
20.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,010 reviews)
"Great food, rooms are clean!!"
United States
Rossana
The price is ฿3,681
฿4,491 total
includes taxes & fees
25 Jun - 26 Jun
Tikal Futura Hotel & Convention Center

Mariana's Petit Hotel

Mariana's Petit Hotel
3.0 star property
20.9 km from Santa Ana
9.2 out of 10, Wonderful, (193 reviews)
"Great owner"
United States
kurt
The price is ฿1,467
฿1,790 total
includes taxes & fees
2 Jun - 3 Jun
Mariana's Petit Hotel

Barceló Guatemala City

Barceló Guatemala City
4.5 star property
22.7 km from Santa Ana
9.2 out of 10, Wonderful, (3,326 reviews)
"great hotel, good location."
United States
emma
The price is ฿3,597
฿4,388 total
includes taxes & fees
2 Jul - 3 Jul
Barceló Guatemala City

Casa Aurora

Casa Aurora
3.0 star property
20.9 km from Santa Ana
9.0 out of 10, Wonderful, (197 reviews)
"It was a really nice place enjoyed staying"
United States
Santos
The price is ฿1,791
฿2,185 total
includes taxes & fees
2 Jun - 3 Jun
Casa Aurora

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.6 out of 10, Excellent, (269 reviews)
"Great place"
United States
CHRISTOPHER
The price is ฿4,096
฿4,997 total
includes taxes & fees
5 Jun - 6 Jun
Hotel Vista Quince

In & Out Hotel

In & Out Hotel
3.0 star property
20.9 km from Santa Ana
8.6 out of 10, Excellent, (870 reviews)
"We love staying atbthe In and Out, rooms have AC, very clean, great breakfast and a very reasonable price."
United States
Julian
The price is ฿1,616
฿1,972 total
includes taxes & fees
7 Jun - 8 Jun
In & Out Hotel

Ole España

Ole España
2.5 star property
20.8 km from Santa Ana
9.4 out of 10, Exceptional, (33 reviews)
"I liked the breakfast and clean area"
United States
Juan
The price is ฿1,180
฿1,439 total
includes taxes & fees
2 Jun - 3 Jun
Ole España

Inari Guatemala

Inari Guatemala
3.0 star property
20.8 km from Santa Ana
9.0 out of 10, Wonderful, (102 reviews)
"The breakfast was delicious "
United States
Shannon
The price is ฿1,509
฿1,841 total
includes taxes & fees
2 Jun - 3 Jun
Inari Guatemala

CASA DE LAS FLORES

CASA DE LAS FLORES
2.0 star property
24.7 km from Santa Ana
9.0 out of 10, Wonderful, (27 reviews)
"Beautiful place in the heart of guatemala city"
United States
Devin
The price is ฿959
฿1,170 total
includes taxes & fees
4 Jun - 5 Jun
CASA DE LAS FLORES

Clarion Suites Guatemala City

Clarion Suites Guatemala City
4.0 star property
23.3 km from Santa Ana
9.2 out of 10, Wonderful, (1,031 reviews)
"All in all great place to stay"
Canada
Andrew
The price is ฿3,315
฿4,045 total
includes taxes & fees
5 Jun - 6 Jun
Clarion Suites Guatemala City

Villa Sicilia

Villa Sicilia
2.0 star property
24 km from Santa Ana
8.2 out of 10, Very good, (159 reviews)
"Second time staying there, and it’s 100% nice place."
United States
Sergio
The price is ฿839
฿1,024 total
includes taxes & fees
8 Jun - 9 Jun
Villa Sicilia

L Aurora Inn

L Aurora Inn
3.0 star property
21 km from Santa Ana
9.0 out of 10, Wonderful, (149 reviews)
"Excellent location for a over night stop.. 3 min walk from terminal… clean and a 24/7 store close by.. fully recommend"
United Kingdom
David
The price is ฿1,920
฿2,937 total
includes taxes & fees
22 Jun - 23 Jun
L Aurora Inn

Kawilal Hotel

Kawilal Hotel
3.5 star property
13.9 km from Santa Ana
9.0 out of 10, Wonderful, (144 reviews)
"Great place to spend some family vacations. Good staff, really good breakfast option. The food (lunch and dinner) a little bit expensive."
United States
David
The price is ฿3,686
฿4,497 total
includes taxes & fees
3 Jun - 4 Jun
Kawilal Hotel

Dai Nonni Hotel

Dai Nonni Hotel
3.0 star property
22.4 km from Santa Ana
9.2 out of 10, Wonderful, (360 reviews)
"The staff was wonderful and very helpful. The breakfast was good and we were able to walk to the artisan market nearby. The hotel was beautifully decorated."
Canada
Chatlene
The price is ฿1,983
฿2,419 total
includes taxes & fees
6 Jun - 7 Jun
Dai Nonni Hotel

Hostal Donde Regina

Hostal Donde Regina
3.0 star property
21 km from Santa Ana
9.0 out of 10, Wonderful, (195 reviews)
"Clean room, close to the airport"
Australia
Veronica
The price is ฿1,622
฿1,979 total
includes taxes & fees
4 Jun - 5 Jun
Hostal Donde Regina

Best Western Plus Hotel Stofella

Best Western Plus Hotel Stofella
4.0 star property
23.3 km from Santa Ana
8.8 out of 10, Excellent, (1,003 reviews)
"Great place to stay"
United States
Miriam
The price is ฿3,288
฿4,011 total
includes taxes & fees
14 Jun - 15 Jun
Best Western Plus Hotel Stofella
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favourite place to stay in Santa Ana?
Based on our traveller data, Casa Buho B&B is one of the top choices for your stay in Santa Ana. This hotel offers a restaurant and free parking.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 14 hotels and other accommodation options in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.