Santa Ana Travel Guide

Antigua Guatemala

Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.

Popular places to visit

Things to do


Top hotels in Santa Ana

Casa Buho B&B

Casa Buho B&B

3 out of 5
77 Calle del Agua Antigua Guatemala Guatemala
The price is ฿1,660 per night from 7 Jun to 8 Jun
฿1,660
฿2,025 total
7 Jun - 8 Jun
includes taxes & fees
Stay at this hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and daily housekeeping. Popular attractions Casa Santo Domingo Museum and Central Park ...
Casa Buho B&B
Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is ฿3,741 per night from 21 Jun to 22 Jun
฿3,741
฿4,565 total
21 Jun - 22 Jun
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
9.2/10 Wonderful! (3,318 reviews)
"It was everything good."

Reviewed on 21 May 2026

Barceló Guatemala City
Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center

4.5 out of 5
Calzada Roosevelt 22-43 Guatemala City Guatemala
The price is ฿3,688 per night from 24 May to 25 May
฿3,688
฿4,499 total
24 May - 25 May
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
9.2/10 Wonderful! (1,001 reviews)
"clean"

Reviewed on 21 May 2026

Tikal Futura Hotel & Convention Center
Clarion Suites Guatemala City

Clarion Suites Guatemala City

4 out of 5
14 Street 3-08 Zona 10 Guatemala City Guatemala
The price is ฿3,048 per night from 23 May to 24 May
฿3,048
฿3,719 total
23 May - 24 May
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,019 reviews)
"Just a pool and everything is complete"

Reviewed on 21 May 2026

Clarion Suites Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is ฿7,777 per night from 21 Jun to 22 Jun
฿7,777
฿9,886 total
21 Jun - 22 Jun
includes taxes & fees
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,060 reviews)
"Everything was so nice! I can’t wait to back."

Reviewed on 21 May 2026

Hotel Museo Spa Casa Santo Domingo
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is ฿6,195 per night from 31 May to 1 Jun
฿6,195
฿8,373 total
31 May - 1 Jun
includes taxes & fees
Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
9.6/10 Exceptional! (1,003 reviews)
"No funcionaba el aire acondicionado y nunca dijeron nada Muy mal"

Reviewed on 21 May 2026

Hotel Camino Real Antigua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Barrio de La Concepción
The Santa Catalina arch and the main street of Antigua city at sunrise, Guatemala.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Historic Center


Santa Ana Travel Guide