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Panama Accommodation: Most Popular Cities to Stay

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Panama City

Panama City

Check availability on Panama Spa Hotels

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Panama hotels with a spa

Steam room, body treatments, body wraps, body scrubs, facials
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1001)
"Everything was clean and the staff was very cooperative."
United States
Deangelo
The price is ฿4,941
฿5,435 total
includes taxes & fees
3 Jan - 4 Jan 2026
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Exterior
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen
8.4 out of 10, Very good, (2333)
"Great breakfast was included and the airport shuttle was conveniently located "
United States
Adrienne
The price is ฿3,418
฿3,760 total
includes taxes & fees
8 Jan - 9 Jan 2026
Crowne Plaza Panama Airport by IHG
Couples treatment room(s), steam room, Turkish bath/hammam
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (644)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ฿6,968
฿7,665 total
includes taxes & fees
25 Jan - 26 Jan 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1001)
"Great hotel and staff!"
United States
Catherine
The price is ฿5,003
฿5,503 total
includes taxes & fees
2 Jan - 3 Jan 2026
Marriott Panama Hotel
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1000)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is ฿6,234
฿6,857 total
includes taxes & fees
14 Jan - 15 Jan 2026
Bristol Panama, a Registry Collection Hotel
Meeting facility
W Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1004)
"Great vibes"
United States
Ashley
The price is ฿6,687
฿7,356 total
includes taxes & fees
9 Jan - 10 Jan 2026
W Panama
Couples treatment room(s), Turkish bath/hammam, body treatments
Radisson Colon 2,000 Hotel & Casino

Radisson Colon 2,000 Hotel & Casino

Radisson Colon 2,000 Hotel & Casino
4.0 star property
Barrio Sur
8.2 out of 10, Very good, (828)
"Check in was very speedy and welcoming . Javier at the front desk was easy to understand and friendly . Room was nice and bed was comfortable ."
United States
SEAN
The price is ฿2,808
฿3,089 total
includes taxes & fees
28 Dec - 29 Dec
Radisson Colon 2,000 Hotel & Casino
Couples treatment room(s), body treatments, aromatherapy
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (565)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is ฿11,357
฿12,493 total
includes taxes & fees
13 Jan - 14 Jan 2026
Sofitel Legend Casco Viejo, Panama City
Couples treatment room(s), sauna, hot tub, Turkish bath/hammam
Sheraton Grand Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (996)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is ฿4,167
฿4,584 total
includes taxes & fees
11 Jan - 12 Jan 2026
Sheraton Grand Panama
Sports facility
Hilton Panama

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1000)
"Nice room! Clean. Nice balcony, "
United States
Cassandra
The price is ฿6,261
฿6,887 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

10/10 Excellent
"Room was very nice, staff couldn't be friendlier, they were super nice 👍 "
Rose Marie 4-night trip
Posted 1 day ago
Dreams Playa Bonita Panama - All Inclusive