Cheap Flights from Panamá Province from ฿4,320

View ฿4,320 flight on Sun, 12 Apr 2026Opens in a new window

Popular airlines from Panamá Province

  • Avianca

  • United

  • American Airlines

  • Delta

  • Copa

  • Aeromexico

  • KLM

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 40% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Panamá Province

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sun, 12 Apr - Tue, 14 Apr
PTY
Panama City
MDE
Medellin
฿10,370 Return, found 4 days ago
฿10,370
Return
found 4 days ago
Select Copa flight, departing Sun, 12 Apr from Panama City to Medellin, returning Tue, 14 Apr, priced at ฿10,370 found 4 days ago
Aeromexico
Fri, 3 Apr - Sat, 11 Apr
PTY
Panama City
CUN
Cancun
฿10,455 Return, found 6 days ago
฿10,455
Return
found 6 days ago
Select Aeromexico flight, departing Fri, 3 Apr from Panama City to Cancun, returning Sat, 11 Apr, priced at ฿10,455 found 6 days ago
Copa
Thu, 26 Mar - Sun, 5 Apr
PTY
Panama City
MDE
Medellin
฿10,705 Return, found 5 days ago
฿10,705
Return
found 5 days ago
Select Copa flight, departing Thu, 26 Mar from Panama City to Medellin, returning Sun, 5 Apr, priced at ฿10,705 found 5 days ago
avianca
Sun, 12 Apr - Tue, 14 Apr
PTY
Panama City
MDE
Medellin
฿10,735 Return, found 4 days ago
฿10,735
Return
found 4 days ago
Select avianca flight, departing Sun, 12 Apr from Panama City to Medellin, returning Tue, 14 Apr, priced at ฿10,735 found 4 days ago
Copa
Sat, 9 May - Wed, 13 May
PTY
Panama City
MDE
Medellin
฿11,090 Return, found 19 hours ago
฿11,090
Return
found 19 hours ago
Select Copa flight, departing Sat, 9 May from Panama City to Medellin, returning Wed, 13 May, priced at ฿11,090 found 19 hours ago
Copa
Sun, 12 Apr - Tue, 14 Apr
PTY
Panama City
MDE
Medellin
฿11,240 Return, found 4 days ago
฿11,240
Return
found 4 days ago
Select Copa flight, departing Sun, 12 Apr from Panama City to Medellin, returning Tue, 14 Apr, priced at ฿11,240 found 4 days ago
Copa
Sat, 9 May - Wed, 13 May
PTY
Panama City
MDE
Medellin
฿11,420 Return, found 19 hours ago
฿11,420
Return
found 19 hours ago
Select Copa flight, departing Sat, 9 May from Panama City to Medellin, returning Wed, 13 May, priced at ฿11,420 found 19 hours ago
avianca
Sat, 9 May - Wed, 13 May
PTY
Panama City
MDE
Medellin
฿11,445 Return, found 19 hours ago
฿11,445
Return
found 19 hours ago
Select avianca flight, departing Sat, 9 May from Panama City to Medellin, returning Wed, 13 May, priced at ฿11,445 found 19 hours ago
American Airlines
Thu, 5 Mar - Mon, 9 Mar
PTY
Panama City
MIA
Miami
฿18,650 Return, found 1 day ago
฿18,650
Return
found 1 day ago
Select American Airlines flight, departing Thu, 5 Mar from Panama City to Miami, returning Mon, 9 Mar, priced at ฿18,650 found 1 day ago
Delta
Thu, 5 Mar - Mon, 9 Mar
PTY
Panama City
MIA
Miami
฿23,525 Return, found 1 day ago
฿23,525
Return
found 1 day ago
Select Delta flight, departing Thu, 5 Mar from Panama City to Miami, returning Mon, 9 Mar, priced at ฿23,525 found 1 day ago
*Available to Expedia members.