Find hotels in Santa Clara from ฿692

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Clara hotels

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.4 out of 10, Very good, (1,856 reviews)
"Property was good, would stay there again. "
United States
Juan
The price is ฿4,327
฿4,760 total
includes taxes & fees
14 Apr - 15 Apr
Riande Aeropuerto Hotel & Casino

Hotel Costa Inn

Hotel Costa Inn
3.0 star property
Calidonia
7.0 out of 10, Good, (576 reviews)
"I love the place it’s near some places it’s my second time staying there "
United States
Adriany
The price is ฿961
฿1,057 total
includes taxes & fees
17 Apr - 18 Apr
Hotel Costa Inn

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista
9.0 out of 10, Wonderful, (198 reviews)
"Amenities, staff, cleanliness, price all excellent!"
United States
Christopher
The price is ฿1,178
฿1,295 total
includes taxes & fees
11 Apr - 12 Apr
Panama House Bed & Breakfast

Hotel Latino

Hotel Latino
3.0 star property
Calidonia
6.6 out of 10, (236 reviews)
"No me gusto"
United States
Omar
The price is ฿779
฿856 total
includes taxes & fees
10 May - 11 May
Hotel Latino

Hotel Acapulco

Hotel Acapulco
3.0 star property
Calidonia
7.6 out of 10, Good, (140 reviews)
"The hotel staff were nice and rhe room was clean and as expected for a budget hotel in this part of town, my issue is with the attached restruant. The staff are rude and ufreindly and refused to give me my jubilado discout that is the law and that I have the right identification for. Shameful disrespect to a panamanian resident."
Canada
James
The price is ฿834
฿917 total
includes taxes & fees
11 Apr - 12 Apr
Hotel Acapulco

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (685 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ฿8,635
฿9,499 total
includes taxes & fees
2 May - 3 May
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Hotel Vía España

Hotel Vía España
3.0 star property
Calidonia
6.2 out of 10, (181 reviews)
"Everything you need for the price!"
United States
Warren
The price is ฿969
฿1,065 total
includes taxes & fees
17 Apr - 18 Apr
Hotel Vía España

Hotel Pension Corona

Hotel Pension Corona
2.5 star property
Calidonia
7.8 out of 10, Good, (118 reviews)
"Great spot for the price "
United States
frank
The price is ฿629
฿692 total
includes taxes & fees
12 Apr - 13 Apr
Hotel Pension Corona

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (261 reviews)
"All units are very well equipped with everything that travelers will need. Comfortable and well located, easy access and safe neighborhood. "
United States
Jaime
The price is ฿3,845
฿5,710 total
includes taxes & fees
23 Apr - 24 Apr
Arcadia Condo Suites

Hotel Marparaiso

Hotel Marparaiso
3.0 star property
Calidonia
7.8 out of 10, Good, (170 reviews)
"I love the hotel and ever thing about it ,location transport, safe around the hotle ."
United States
Andres
The price is ฿1,165
฿1,282 total
includes taxes & fees
18 Apr - 19 Apr
Hotel Marparaiso

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.2 out of 10, Very good, (243 reviews)
"It’s always a pleasure to stay at the Marinn Tropical every time I visit Panamá City. "
United States
Lori
The price is ฿3,208
฿3,529 total
includes taxes & fees
22 Apr - 23 Apr
MARINN Tropical Vibes Hotel

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (189 reviews)
"It's meant for a short stay, close to Casco Viejo and coast line. Clean bed and bathroom. Needs some maintenance. Beware, there's no hot water if that's a deal breaker for you."
United States
Mario
The price is ฿937
฿1,031 total
includes taxes & fees
27 Apr - 28 Apr
Hotel República

Canova

Canova
3.0 star property
Calidonia
8.2 out of 10, Very good, (155 reviews)
"Plenty of shops nearby , decent area. The staff was pretty nice . "
United States
Lazaria
The price is ฿936
฿1,029 total
includes taxes & fees
10 May - 11 May
Canova

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,256 reviews)
"Great place to stay, great staff, I had a good time in the hotel itself "
United States
Walana
The price is ฿3,938
฿4,332 total
includes taxes & fees
7 May - 8 May
Hotel Riu Plaza Panama

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,006 reviews)
"Nice hotel will visit again"
United States
Deisha
The price is ฿3,513
฿3,865 total
includes taxes & fees
3 May - 4 May
Courtyard by Marriott Panama Metromall

Residencial & Hotel Palazzo

Residencial & Hotel Palazzo
3.0 star property
Calidonia
7.4 out of 10, Good, (130 reviews)
"I recommend this place"
United States
Crystal
The price is ฿1,100
฿1,210 total
includes taxes & fees
10 May - 11 May
Residencial & Hotel Palazzo

Hotel Montreal

Hotel Montreal
3.5 star property
Bella Vista
6.0 out of 10, (414 reviews)
"The room was in good condition; the staff was very helpful."
United States
VELVETT
The price is ฿920
฿1,012 total
includes taxes & fees
13 Apr - 14 Apr
Hotel Montreal

Euro Hotel

Euro Hotel
3.0 star property
Calidonia
7.8 out of 10, Good, (646 reviews)
"Friendly staff Good location Fair price"
Canada
Katherine
The price is ฿1,218
฿1,339 total
includes taxes & fees
9 May - 10 May
Euro Hotel

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,165 reviews)
"Clean, spacious rooms, very nice and welcoming staff. Great breakfast. "
United States
Erica
The price is ฿3,140
฿3,454 total
includes taxes & fees
6 May - 7 May
Ramada Plaza by Wyndham Panama Punta Pacifica

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (327 reviews)
"Clean room, helpful staff, good breakfast."
United States
Stephanie
The price is ฿6,861
฿7,547 total
includes taxes & fees
10 May - 11 May
The Westin Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santa Clara attractions

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history and more!

Adobe

Top Santa Clara Hotel Reviews

More cheap stays in Santa Clara

Frequently asked questions

What's the best place to stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Sheraton Grand Panama and W Panama. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer, including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1353 hotels and other accommodation options in the surrounding area. Find out more about Santa Clara.
What should I do while I'm visiting Santa Clara?
A favourite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Clara guide.
What's the weather like in Santa Clara?
The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Santa Clara are July, August, November and October, with each month seeing an average of 283 mm of rainfall.