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Top 10 Santa Clara hotels and places to stay

Central Hotel Panama Casco Viejo
4.0 star property
9.2 out of 10, Wonderful, (1008)
"Very beautiful hotel with helpful staff. Very good dining options. "
United States
Joseph
The price is ฿9,349
฿10,284 total
includes taxes & fees
18 Nov - 19 Nov
Central Hotel Panama Casco Viejo
La Concordia Boutique Hotel
4.0 star property
9.4 out of 10, Exceptional, (188)
"Clean, safety, nice staff, decoration and quite building "
United States
Claudia
The price is ฿6,235
฿6,859 total
includes taxes & fees
29 Oct - 30 Oct
La Concordia Boutique Hotel
Hotel Coral Suites
3.5 star property
9.0 out of 10, Wonderful, (1004)
"This place is nice for a overnight stay"
United States
Gwendolyn
The price is ฿2,263
฿2,489 total
includes taxes & fees
2 Nov - 3 Nov
Hotel Coral Suites
TRYP by Wyndham Panamá Centro
3.5 star property
9.2 out of 10, Wonderful, (1006)
"Great affordable dining and service "
United States
Sean
The price is ฿2,747
฿3,022 total
includes taxes & fees
5 Nov - 6 Nov
TRYP by Wyndham Panamá Centro
Riande Aeropuerto Hotel & Casino
4.0 star property
8.6 out of 10, Excellent, (1892)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is ฿5,621
฿6,183 total
includes taxes & fees
7 Nov - 8 Nov
Riande Aeropuerto Hotel & Casino
Principe Hotel and Suites
3.0 star property
9.0 out of 10, Wonderful, (1547)
"A nice hotel with plenty of shopping and restaurants in the area"
United States
Neil
The price is ฿1,633
฿1,796 total
includes taxes & fees
7 Nov - 8 Nov
Principe Hotel and Suites
Novotel Panama City
4.0 star property
9.2 out of 10, Wonderful, (1044)
"Friendly staff and a great variety in the buffet."
United States
Zoraida
The price is ฿3,203
฿3,524 total
includes taxes & fees
7 Nov - 8 Nov
Novotel Panama City
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1014)
"great stay when in PTY"
United States
Fernando
The price is ฿6,123
฿6,735 total
includes taxes & fees
28 Nov - 29 Nov
Bristol Panama, a Registry Collection Hotel
Ramada Panama Centro Via Argentina
3.0 star property
7.4 out of 10, Good, (258)
"Hotel staff and rooms were good , great location "
United States
Cornelly
The price is ฿2,221
฿2,443 total
includes taxes & fees
4 Nov - 5 Nov
Ramada Panama Centro Via Argentina
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, (651)
"Yes Ac work well and everything works out well Place is lovely and great service "
United States
Sandy
The price is ฿1,710
฿1,881 total
includes taxes & fees
29 Oct - 30 Oct
Hospedium Princess Hotel Panama
Gamboa Rainforest Reserve
3.5 star property
7.8 out of 10, Good, (649)
"We had a lovely stay, the views and tranquility of the place was my favorite part."
United States
Rebecca
The price is ฿3,791
฿4,170 total
includes taxes & fees
30 Oct - 31 Oct
Gamboa Rainforest Reserve
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (620)
"The staff were fantastic. The service was great. "
United States
SANDRO
The price is ฿6,721
฿7,393 total
includes taxes & fees
23 Nov - 24 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (871)
"Was please with the hospitality and the front desk staff Aaron was very professional and informative "
United States
Latoya
The price is ฿3,821
฿4,203 total
includes taxes & fees
3 Nov - 4 Nov
Aloft Panama
Courtyard by Marriott Panama Metromall
4.0 star property
8.8 out of 10, Excellent, (1003)
"Always a great hotel, forth time back"
United States
Juan
The price is ฿3,581
฿3,939 total
includes taxes & fees
21 Nov - 22 Nov
Courtyard by Marriott Panama Metromall
Hotel La Compañía Casco Antiguo
4.5 star property
9.8 out of 10, Exceptional, (240)
"Excellent location."
Canada
Kenneth
The price is ฿9,576
฿10,534 total
includes taxes & fees
5 Nov - 6 Nov
Hotel La Compañía Casco Antiguo
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
8.8 out of 10, Excellent, (1007)
"Perfect stay "
United States
pedro
The price is ฿4,003
฿4,404 total
includes taxes & fees
1 Nov - 2 Nov
Courtyard by Marriott Panama Multiplaza Mall
Plaza Paitilla Inn Hotel
3.5 star property
9.4 out of 10, Exceptional, (2119)
"great property and staff "
United States
Yunior
The price is ฿5,163
฿5,679 total
includes taxes & fees
29 Oct - 30 Oct
Plaza Paitilla Inn Hotel
W Panama
5.0 star property
9.0 out of 10, Wonderful, (1001)
"Awesome place "
United States
Rainier
The price is ฿5,853
฿6,439 total
includes taxes & fees
28 Nov - 29 Nov
W Panama
Hotel San Felipe
4.0 star property
9.4 out of 10, Exceptional, (217)
"It’s in the heart of the city, great place to stay "
United States
Kenny
The price is ฿4,761
฿5,237 total
includes taxes & fees
4 Nov - 5 Nov
Hotel San Felipe
JW Marriott Panama
5.0 star property
9.0 out of 10, Wonderful, (1009)
"The rooms were amazing "
United States
Andrae Kevin
The price is ฿6,911
฿7,603 total
includes taxes & fees
7 Nov - 8 Nov
JW Marriott Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Dreams Playa Bonita Panama - All Inclusive and Megapolis Hotel Panamá. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer, including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1515 hotels and other accommodation options in the surrounding area. Find out more about Santa Clara.
What should I do while I'm visiting Santa Clara?
A favourite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Clara guide.
What's the weather like in Santa Clara?
The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Santa Clara are July, August, November and October, with each month seeing an average of 283 mm of rainfall.