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Check prices for these dates

In two weeks
3 Jul - 5 Jul
In two months
14 Aug - 16 Aug
In three months
11 Sep - 13 Sep
In four months
9 Oct - 11 Oct

Our top choices for Santa Clara holiday rentals

50-inch LED TV with satellite channels

Arcadia Condo Suites

Arcadia Condo Suites
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (305 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is ฿3,010
฿5,042 total
includes taxes & fees
2 Jul - 3 Jul
Arcadia Condo Suites
Front of property

Modern Apartments at the Hub City views

Modern Apartments at the Hub City views
3.0 star property
San Francisco
The price is ฿1,938
฿2,131 total
includes taxes & fees
3 Jul - 4 Jul
Modern Apartments at the Hub City views
Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.6 out of 10, Good, (202 reviews)
"Host was very good at responding to any questions we had to make the most of our stay!!"
United States
Katrina
The price is ฿1,499
฿6,246 total
includes taxes & fees
24 Jun - 25 Jun
Boutique Apartments Panamá Coco del Mar
Outdoor pool

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.5 star property
San Francisco
8.4 out of 10, Very good, (15 reviews)
"Great stay. Friendly staff"
Canada
Ani
The price is ฿4,705
฿5,176 total
includes taxes & fees
21 Jun - 22 Jun
Dovle Residences by HMS-Preferred Member
Apartment (10D) | Balcony

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (56 reviews)
"Clean and walkable location"
United States
Tamera
The price is ฿3,592
฿4,853 total
includes taxes & fees
28 Jun - 29 Jun
San Francisco by Wynwood House
Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets

La Palma Experience

La Palma Experience
3.0 star property
Amador
8.4 out of 10, Very good, (8 reviews)
"Air conditioner has good working. People are nice and good response for us. Basically room are clean but I can see small ants some of them on the table and on floor. I doesn't matter for it. In neighbor restaurant made big sounds at night to midnight."
Japan
Shuntaro
The price is ฿1,915
฿2,107 total
includes taxes & fees
21 Jun - 22 Jun
La Palma Experience
Exterior

Luxury City View Apartments at Worldwide

Luxury City View Apartments at Worldwide
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (1 review)
"I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended."
United States
Andre
The price is ฿2,213
฿2,435 total
includes taxes & fees
21 Jun - 22 Jun
Luxury City View Apartments at Worldwide
Interior detail

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (204 reviews)
"Beautiful place to stay and near to everything. The place is very clean and safe. We had a wonderful time there! :)"
Canada
Mariela
The price is ฿5,164
฿5,681 total
includes taxes & fees
1 Jul - 2 Jul
La Isabela Suites
Design Apartment, Balcony, Partial Ocean View | Living area | 55-inch Smart TV with digital channels, Netflix, streaming services

Modern Apartments at The Gray Prime Location

Modern Apartments at The Gray Prime Location
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (2 reviews)
"Close to attractions and great restaurants"
United States
Tiyania
The price is ฿2,683
฿2,951 total
includes taxes & fees
22 Jun - 23 Jun
Modern Apartments at The Gray Prime Location
Outdoor dining

Refugio Frente al Mar Vista Venao

Refugio Frente al Mar Vista Venao
3.0 star property
Veracruz
The price is ฿2,131
฿2,344 total
includes taxes & fees
21 Jun - 22 Jun
Refugio Frente al Mar Vista Venao
Apartment (17F) | Living area | TV

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
8.0 out of 10, Very good, (1 review)
"Review checkin process. Find entry codes and details about key fobs. Find out if there is construction next door as i was awaken every morning at 7am by construction noise. Verify everything works upon entry and request immediate fix. I was without internet for a day and had to wait various days for repairmen to come fix things without having a set time for their visit. Great place to stay. Walking distance of many things and great amenities but had some minor inconveniences. Staff was very...
United States
Will
The price is ฿979
฿6,080 total
includes taxes & fees
21 Jun - 22 Jun
Living 73 Panamá by Boutique Apartments
Restaurant

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (194 reviews)
"Best location. Beautiful heritage place and lovely restaurant attached."
United States
Kc
The price is ฿4,049
฿4,454 total
includes taxes & fees
19 Jul - 20 Jul
Las Clementinas
Outdoor pool

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.8 out of 10, Good, (315 reviews)
"Great location"
United States
sasha
The price is ฿974
฿4,658 total
includes taxes & fees
22 Jun - 23 Jun
Boutique Apartments Panama
Apartment (14D) | Dining room

Mini Design By Wynwood House

Mini Design By Wynwood House
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (2 reviews)
"The pool is amazing. I love that is it long enough to do laps if one would like a workout."
United States
Monica
The price is ฿3,567
฿4,826 total
includes taxes & fees
21 Jun - 22 Jun
Mini Design By Wynwood House
Exterior

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
7.8 out of 10, Good, (102 reviews)
"Friendly staff "
United States
Charles
The price is ฿2,017
฿6,801 total
includes taxes & fees
21 Jun - 22 Jun
Yoo Panamá by Boutique Apartments
Private beach

Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
3.0 star property
Vacamonte
8.4 out of 10, Very good, (5 reviews)
"Really recommended! Omar is a superhost, very helpfull and lovely! Good facilities and there is a swimmingpool and a nice little beach."
United States
Cynthia
The price is ฿708
฿1,091 total
includes taxes & fees
30 Jun - 1 Jul
Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
Outdoor pool

Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
3.5 star property
Bella Vista
The price is ฿3,305
฿3,636 total
includes taxes & fees
1 Jul - 2 Jul
Yoo Panama Luxury Ocean View Apartment
Outdoor pool

Apartments at The Sands – Ocean View Panama City

Apartments at The Sands – Ocean View Panama City
3.0 star property
Calidonia
6.8 out of 10, (6 reviews)
"Good location is good!"
United States
Ivy
The price is ฿2,213
฿2,435 total
includes taxes & fees
22 Jun - 23 Jun
Apartments at The Sands – Ocean View Panama City
Front of property

La Résidence Panamá

La Résidence Panamá
2.5 star property
Bella Vista
9.2 out of 10, Wonderful, (19 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is ฿4,987
฿5,486 total
includes taxes & fees
22 Jun - 23 Jun
La Résidence Panamá
Reception

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (554 reviews)
"Breakfast was one of the best ive been to"
United States
Tron
The price is ฿3,033
฿3,336 total
includes taxes & fees
21 Jun - 22 Jun
Torres de Alba Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Clara Hotel Reviews

Megapolis Hotel Panamá

Megapolis Hotel Panamá

10/10 Excellent
"This is not my first stay here, and it certainly won't be my last. My family and I continue to choose this hotel because of the spacious rooms, great value, and consistently outstanding service. The staff is always friendly and welcoming, and the valet team deserves special recognition for their professionalism, kindness, and prompt service. They truly make every visit feel special. Highly recommended!"
Carlos Rodrigo 1-night trip
Posted 1 hour ago
Megapolis Hotel Panamá

Find out more about Santa Clara

Search for holiday rentals in Santa Clara on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Clara using one of the methods below:

  • View our selection of featured holiday rentals in Santa Clara
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  • Enter your travel dates to view the best deals on holiday rentals in Santa Clara while they last

Look no further and take a look at our great range of rental properties in Santa Clara!

Frequently asked questions

Can I find holiday rentals in Santa Clara?

Yes, there are holiday rentals close to the most popular sights in Santa Clara, or you can select a more secluded option if you're looking for a relaxing stay. Santa Clara is known for its monuments.

What can I see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Summit Botanical Gardens & Zoo, or get outside and enjoy nature at Culebra Cut. In the wider area, you’ll find Albrook Shopping Mall and Gamboa Rainforest Resort.

What are holiday rentals like in Santa Clara?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Clara. Holiday rentals offer extras like laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about cleanliness, holiday rentals can provide a sense of privacy away from shared hotel lifts and busy lobbies while still allowing you to travel. You'll also have more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular option for a family trip or a small group gathering.