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Panama Accommodation: Most Popular Cities to Stay

A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.
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Panama City

Panama City

Check availability on Panama Spa Hotels

This weekend
7 Aug - 9 Aug
Next weekend
14 Aug - 16 Aug

Our top choices for Panama hotels with a spa

Meeting facility

1. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,005 reviews)
  • cleanliness
    Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.
The price is ฿5,129
฿5,642 total
includes taxes & fees
9 Aug - 10 Aug
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Exterior

2. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen
8.6 out of 10, Excellent, (2,636 reviews)
The price is ฿4,488
฿5,157 total
includes taxes & fees
6 Sept - 7 Sept
Crowne Plaza Panama Airport by IHG
Lobby lounge

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (724 reviews)
  • cleanliness
    Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.
The price is ฿7,705
฿8,475 total
includes taxes & fees
7 Aug - 8 Aug
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
2 bars/lounges, poolside bar

4. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1,003 reviews)
The price is ฿5,030
฿5,533 total
includes taxes & fees
6 Sept - 7 Sept
Marriott Panama Hotel
Couples treatment room(s), sauna, steam room, body treatments

5. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.
The price is ฿7,416
฿8,158 total
includes taxes & fees
28 Aug - 29 Aug
Bristol Panama, a Registry Collection Hotel
Spa

6. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,006 reviews)
  • cleanliness
    Revitalise at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting.
The price is ฿9,233
฿10,156 total
includes taxes & fees
5 Sept - 6 Sept
W Panama
Couples treatment room(s), Turkish bath/hammam, body treatments

7. Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
4.0 star property
Barrio Sur
8.2 out of 10, Very good, (965 reviews)
  • cleanliness
    Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
Couples treatment room(s), body treatments, aromatherapy

8. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (708 reviews)
  • cleanliness
    Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
The price is ฿12,567
฿13,824 total
includes taxes & fees
24 Aug - 25 Aug
Sofitel Legend Casco Viejo, Panama City
Couples treatment room(s), sauna, hot tub, Turkish bath/hammam

9. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await.
The price is ฿5,659
฿6,225 total
includes taxes & fees
28 Aug - 29 Aug
Sheraton Grand Panama
Reception

10. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,004 reviews)
  • cleanliness
    Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
The price is ฿7,842
฿8,626 total
includes taxes & fees
5 Sept - 6 Sept
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

8/10 Good
"The hotel is as the name indicated, in the center of old town. The location is fantastic. Very convenient. However, as some of the reviews had mentioned, they have live music in the lobby all day until 11pm. I was aware of this and requested that they give us a quiet room. However, we were given a room with windows facing the atrium and were subjected to the music all day. It was not too loud but was quite annoying if you want quietness. Add to this, it was on the 4th floor and next to one of the restaurant/bar and there were noises coming from it until late. The room was 426 so to other travelers, avoid this room. The bathroom shower was poorly designed and the floor was flooded after every shower. We had to use tons to towels to mop up the water. Not sure why we were given such a lousy room even though the hotel didn’t seem fully booked. The only reason I didn’t request for another room because my husband has unpacked all his stuffs and didn’t want to move. Are Expedia customers treated worse or something? The positives: the room was reasonably spacious. Beddings were comfortable. Roof top pool was nice although it is rather of small and it could use some fixing up. The staff was courteous and breakfast was decent. Had it not for the noisy room, it would have been a nice stay. For this reason, I don’t think we’ll stay here again in the future since noisy room is a deal breaker for me."
Thuy-Linh 3-night trip
Posted 2 hours ago
Central Hotel Panama Casco Viejo