A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

4 Stars Hotels in Panama City

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Check availability on Panama City 4 Star Hotels

Tonight
15 Oct - 16 Oct
Tomorrow
16 Oct - 17 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Panama City 4-star hotels

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.

1. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
United States
Duran
฿4,574
฿5,254 total
includes taxes & fees
9 Nov - 10 Nov
Crowne Plaza Panama Airport by IHG
A multi-story building with balconies, arched windows, and decorative railings.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

2. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
฿7,492
฿8,241 total
includes taxes & fees
9 Nov - 10 Nov
Central Hotel Panama Casco Viejo
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A modern spa area with a hot tub, seating, and a city view.
A rooftop pool area with purple lounge chairs and a city skyline in the background.
A rooftop lounge with modern seating and a panoramic city view.

3. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
benjamin
฿5,373
฿5,910 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
Pool
A reception area with marble reception desks and a sign indicating the reception desk.
A buffet area with a variety of dishes, a long counter with food, and a seating area with tables and chairs.
A hotel room with a large bed, a smaller bed, a sofa, a TV mounted on the wall, and a dining area with a table and chairs.

4. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
Althea
฿4,056
฿4,462 total
includes taxes & fees
8 Nov - 9 Nov
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
A balcony with wicker chairs and a view of the cityscape.
A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.
A rooftop pool area with a view of high-rise buildings in the background.

5. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Luis
฿3,202
฿3,522 total
includes taxes & fees
9 Nov - 10 Nov
Ramada Plaza by Wyndham Panama Punta Pacifica
A resort with a large swimming pool, thatched-roof structures, and palm trees.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
A resort with a pool, palm trees, and a building with a red roof.

6. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Babak
฿9,342
฿9,342 total
includes taxes & fees
16 Oct - 17 Oct
Dreams Playa Bonita Panama - All Inclusive
A trampoline with a safety net in a grassy area with trees in the background.
A swimming pool with a bridge, surrounded by lush greenery and a seating area with tables and chairs.
A conference room with a long table, chairs, and a carpeted floor.
A reception area with a receptionist, a statue, and a digital display.

7. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
United States
Lucas
฿3,634
฿3,997 total
includes taxes & fees
26 Oct - 27 Oct
Riande Aeropuerto Hotel & Casino
A modern building with a glass facade, a curved structure, and a flat roof.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.

8. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Jorge Luis
฿2,920
฿3,212 total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A buffet with various food items including fruits, juices, and cheeses.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.
A gym with treadmills, weight machines, and dumbbells.

9. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Chaloma
฿3,404
฿3,744 total
includes taxes & fees
30 Oct - 31 Oct
Courtyard by Marriott Panama Metromall
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.
A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.

10. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
SHARROW
฿3,966
฿4,363 total
includes taxes & fees
31 Oct - 1 Nov
Courtyard by Marriott Panama Multiplaza Mall
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
An indoor swimming pool with lounge chairs and a modern interior design.
A spacious lobby with a staircase, seating area, and a bar.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.

11. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
฿5,065
฿5,572 total
includes taxes & fees
14 Nov - 15 Nov
Las Americas Golden Tower Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A buffet setup with various dishes and utensils.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.
A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.

12. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Calvin
฿5,975
฿6,572 total
includes taxes & fees
24 Oct - 25 Oct
Marriott Panama Hotel
A hotel room with a sofa, a coffee table, a TV, and a cabinet.
A hotel room with a large bed, bedside tables with lamps, a chair, and a large window with curtains.
A rooftop swimming pool with lounge chairs and a city skyline in the background.
A cityscape with modern high-rise buildings, including a prominent tower labeled 'TOWERBANK.'

13. Studio Coliving

Studio Coliving
Bella Vista
United States
Phillip
Studio Coliving
A rooftop pool with sun loungers and a city skyline in the background.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A long, narrow hallway with a wooden floor and light-colored walls.
A bar area with a curved counter, multiple screens, and a patterned carpet.

14. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
Bruno
฿3,172
฿5,335 total
includes taxes & fees
16 Oct - 17 Oct
Waymore Hotel Spa & Casino
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A buffet setup with various food items, including bread, pastries, and a variety of dishes in bowls.
A hotel room with a bed and a view of a cityscape through sheer curtains.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

15. Novotel Panama City

Novotel Panama City
Bella Vista
United States
CARLOS
฿3,875
฿4,262 total
includes taxes & fees
5 Nov - 6 Nov
Novotel Panama City
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A formal dining area with round tables, white tablecloths, and blue lace borders.
A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.
A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

16. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United States
Si Ming
฿2,625
฿2,888 total
includes taxes & fees
14 Nov - 15 Nov
Radisson Hotel Panama Canal
A buffet with various food items and a decorative plant.
A spa area with a hot tub, candles, and a curved bench.
A hotel with a swimming pool, outdoor seating, and a modern architectural design.
A gym with treadmills, weight machines, and a red carpet.

17. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Nicole
฿6,206
฿6,826 total
includes taxes & fees
1 Nov - 2 Nov
Sheraton Grand Panama
A poolside area with covered seating and palm trees.
A modern interior with a large abstract sculpture, a staircase, a sofa with orange cushions, and a patterned rug.
A modern living room with a city view, a flat-screen TV, and a dining area with white chairs and a table.
A modern hotel lobby with a glass facade, seating area with loungers, and a wooden floor.

18. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Bella Vista
United States
Jahzenia
฿9,048
฿9,953 total
includes taxes & fees
21 Oct - 22 Oct
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.
A white building with multiple balconies, large windows, and decorative railings.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

19. American Trade Hotel

American Trade Hotel
Casco Viejo
United States
Ashleigh-Ann
฿8,262
฿9,089 total
includes taxes & fees
2 Nov - 3 Nov
American Trade Hotel
A wooden door with a number plate, a black and white striped bag, and a lantern on the ground.
A bedroom with a large bed, a stone wall, a wooden bench, and a hanging light fixture.
A restaurant with a wine display and a table set for two.
A rooftop bar with potted plants, seating, and a view of a city skyline.

20. Hotel Casa Panamá

Hotel Casa Panamá
Casco Viejo
United States
Naveera Jyoti
฿2,257
฿2,483 total
includes taxes & fees
26 Oct - 27 Oct
Hotel Casa Panamá
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
฿3,963
฿4,360 total
21 Oct - 22 Oct
includes taxes & fees
9/10 Wonderful! (6,071 reviews)
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
฿8,834
฿9,718 total
7 Nov - 8 Nov
includes taxes & fees
Waldorf Astoria Panama
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste, San Felipe Panama City Panama
฿11,806
฿12,986 total
3 Nov - 4 Nov
includes taxes & fees
Sofitel Legend Casco Viejo, Panama City
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent
"Lovely going back"
Oshin 3-night trip
Posted 13 hours ago
Courtyard by Marriott Panama Multiplaza Mall
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

8/10 Good
"We had a great stay. You can't beat the location. The beds are comfortable and the room was very spacious. The property is clean and well maintained. The biggest issue was the dust. Our room was super dusty, every surface when we checkedn in. They were doing some renos. Even though our suit was away from the main lobby area, we had to sleep with ear plugs since the music traveled from the lobby and we could hear it even in our room. In the morning we also heard all the cleaning staff moving about and doing laundry. Woke is up st 07:30. We also never got our free welcome sparkling wine. They kept sending us from restaurant to restaurant so we eventually gave up."
Anna 1-night trip
Posted 19 hours ago
Central Hotel Panama Casco Viejo

Frequently asked questions

What are the best 4-star hotels in Panama City?
Panama Marriott Hotel is a 4-star hotel in Panama City that's a favourite among Expedia customers. A sauna and massage services are just a couple of its amenities. Travellers also recommend Continental Hotel Panamá. From windsurfing to room service, it offers conveniences that cater to every aspect of your relaxation and enjoyment.
How much does it cost to stay in a 4-star hotel in Panama City?
With Expedia's sort and search filters, bagging a terrific deal on a 4-star hotel in Panama City just got easier. Start by keying in your chosen travel dates and length of your getaway. Then sort the results by price and choose the option that best suits your style and budget.
  • Search for the lowest price from ฿4,360
What's the difference between 5-star and 4-star hotels in Panama City?
Offering an inviting traveller experience and upscale décor, 4-star hotels are a terrific option for your Panama City getaway. These types of accommodation generally come with loads of handy amenities that make it simple to kick back and relax — think pillowtop mattresses, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with luxury perks and amenities. 24-hour front desk, premium toiletries and world-class dining are typically featured at these plush properties.