5 Stars Hotels in Panama City

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Panama City 5 Star Hotels

Top Panama City 5 Star Hotels

Hotel Riu Plaza Panama
Outdoor pool, pool loungers

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4176)
"Very convenient location, friendly staff and all around beautiful hotel."
The price is ฿3,666
฿4,033 total
includes taxes & fees
20 Aug - 21 Aug
Hotel Riu Plaza Panama
JW Marriott Panama
4 outdoor pools, free pool cabanas, pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1006)
"Always an exceptional stay. "
The price is ฿7,145
฿7,860 total
includes taxes & fees
30 Aug - 31 Aug
JW Marriott Panama
The Westin Playa Bonita Panama
3 outdoor pools, pool umbrellas, pool loungers

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very good, (1004)
"Quiet, some good food options, good for a few days escape"
The price is ฿4,998
฿5,498 total
includes taxes & fees
5 Sept - 6 Sept
The Westin Playa Bonita Panama
Sofitel Legend Casco Viejo, Panama City
Exterior

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (489)
"Excellent service, facilities, food and location!"
The price is ฿9,494
฿10,443 total
includes taxes & fees
3 Sept - 4 Sept
Sofitel Legend Casco Viejo, Panama City
Waldorf Astoria Panama
View from property

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1002)
"Lovely stay "
The price is ฿7,274
฿8,001 total
includes taxes & fees
31 Aug - 1 Sept
Waldorf Astoria Panama
W Panama
2 restaurants, local cuisine

W Panama

5.0 star property
8.8 out of 10, Excellent, (1004)
"Great hotel "
The price is ฿6,465
฿7,112 total
includes taxes & fees
30 Aug - 31 Aug
W Panama
Bristol Panama, a Registry Collection Hotel
Couples treatment room(s), sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1003)
"A lovely hotel and excellent food and rooms and service. "
The price is ฿7,084
฿7,792 total
includes taxes & fees
16 Sept - 17 Sept
Bristol Panama, a Registry Collection Hotel
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | 1 bedroom, premium bedding, minibar, in-room safe

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (598)
"The staff was very friendly. "
The price is ฿6,893
฿7,583 total
includes taxes & fees
7 Sept - 8 Sept
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Hilton Panama
Outdoor pool

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"The food was very good at the hotel. Several options to choose from at the hotel. "
The price is ฿6,682
฿7,350 total
includes taxes & fees
23 Aug - 24 Aug
Hilton Panama
Renaissance Panama City Hotel
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

5.0 star property
8.8 out of 10, Excellent, (46)
"Very friendly staff! This will be my go to stay when visiting Panama!"
The price is ฿3,343
฿3,677 total
includes taxes & fees
29 Aug - 30 Aug
Renaissance Panama City Hotel
Megapolis Hotel Panamá
View from property

Megapolis Hotel Panamá

5.0 star property
8.4 out of 10, Very good, (1000)
"This is THE place to stay in Panama City... it's location, friendly accommodating staff, and the amenities are fantastic. The rooms were wonderful, clean and bright. We tried Tauro (steakhouse) and the Bazaar - they were both delicious and the service excellent. We literally partied like rock stars at their rooftop restaurant, and at the wonderful outdoor infinity pool as well. We will definitely be returning! "
Megapolis Hotel Panamá
Waymore Hotel Spa and Casino
Outdoor pool

Waymore Hotel Spa and Casino

5.0 star property
6.2 out of 10, (1000)
"Clean and safe. Lot of security."
Waymore Hotel Spa and Casino
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Sheraton Grand Panama

Sheraton Grand Panama

Via Israel And 77th Street, Panama City, Panama
The price is ฿4,111 per night from 7 Sept to 8 Sept
฿4,111
฿4,522 total
7 Sept - 8 Sept
includes taxes & fees
8.4/10 Very Good! (929 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Staff was great!"
David 3-night trip
Posted 2 days ago
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

10/10 Excellent
"Absolutely amazing from check in to check out. "
Justin 1-night trip
Posted 1 month ago
Waldorf Astoria Panama

Frequently asked questions

What are the best 5-star hotels in Panama City?
According to Expedia guest reviews, Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are among the top 5-star hotels in Panama City. Providing top-quality amenities and unmatchable service, you'll enjoy a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in Panama City?
How much you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to stay, among other factors. Take advantage of our price per night filter and other search tools to find the best deal on a luxurious getaway.

  • Search for the lowest price per night from ฿3,359

What makes a hotel 5 stars in Panama City?
From fine dining restaurants and 24-hour gyms to swimming pools and the finest bedding, the 5-star experience in Panama City is all about comfort and luxury. But it takes more than just top-notch amenities to receive a 5-star rating. Hotels also have to offer remarkable guest-centric services like in-room beauty treatments, on-site laundry and dry cleaning and room service any time day or night.