A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

5 Stars Hotels in Panama City

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Check availability on Panama City 5 Star Hotels

Tonight
11 Sep - 12 Sep
Tomorrow
12 Sep - 13 Sep
This weekend
11 Sep - 13 Sep
Next weekend
18 Sep - 20 Sep

Our top choices for Panama City 5-star hotels

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Lori
฿4,560
฿5,015 total
includes taxes & fees
27 Sept - 28 Sept
Hotel Riu Plaza Panama

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
฿8,808
฿9,688 total
includes taxes & fees
27 Sept - 28 Sept
Waldorf Astoria Panama

3. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Benjamin A
฿8,984
฿9,882 total
includes taxes & fees
3 Oct - 4 Oct
JW Marriott Panama

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
฿4,207
฿4,628 total
includes taxes & fees
18 Sept - 19 Sept
Renaissance Panama City Hotel

5. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
฿13,565
฿14,922 total
includes taxes & fees
20 Sept - 21 Sept
Sofitel Legend Casco Viejo, Panama City

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Abraham
฿6,153
฿6,769 total
includes taxes & fees
20 Sept - 21 Sept
Hyatt Regency Panama City

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
PAULA
฿8,860
฿9,746 total
includes taxes & fees
18 Sept - 19 Sept
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

8. W Panama

W Panama
Bella Vista
United States
Nikkia
฿7,394
฿8,133 total
includes taxes & fees
25 Sept - 26 Sept
W Panama

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Kevin
฿7,687
฿8,456 total
includes taxes & fees
3 Oct - 4 Oct
Hilton Panama

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
Canada
Flavio
฿6,827
฿7,510 total
includes taxes & fees
25 Sept - 26 Sept
The Westin Playa Bonita Panama

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
฿7,011
฿7,712 total
includes taxes & fees
20 Sept - 21 Sept
Bristol Panama, a Registry Collection Hotel

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
฿3,634
฿3,997 total
includes taxes & fees
1 Oct - 2 Oct
Waymore Hotel Spa and Casino

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
฿7,743
฿8,518 total
includes taxes & fees
3 Oct - 4 Oct
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
฿4,041
฿4,664 total
6 Oct - 7 Oct
includes taxes & fees
8.6/10 Excellent! (2,731 reviews)
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
฿6,075
฿6,683 total
11 Oct - 12 Oct
includes taxes & fees
9/10 Wonderful! (1,010 reviews)
Central Hotel Panama Casco Viejo
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama
฿3,125
฿3,438 total
7 Oct - 8 Oct
includes taxes & fees
7.8/10 Good! (1,002 reviews)
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

8/10 Good
"Hotel was ok for the price. I had a draining issue that never got resolved in the 3 days I was there, they offered a room change the last night I was there which i declined as I was checking out the next day. Overall ok."
Alice 3-night trip
Posted 3 hours ago
Hotel Riu Plaza Panama
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"Great"
Mark 2-night trip
Posted 18 hours ago
JW Marriott Panama

Frequently asked questions

What are the best 5-star hotels in Panama City?
According to Expedia guest reviews, Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are among the top 5-star hotels in Panama City. Providing top-quality amenities and unmatchable service, you'll enjoy a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in Panama City?
How much you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to stay, among other factors. Take advantage of our price per night filter and other search tools to find the best deal on a luxurious getaway.
  • Search for the lowest price per night from ฿3,438
What makes a hotel 5 stars in Panama City?
From fine dining restaurants and 24-hour gyms to swimming pools and the finest bedding, the 5-star experience in Panama City is all about comfort and luxury. But it takes more than just top-notch amenities to receive a 5-star rating. Hotels also have to offer remarkable guest-centric services like in-room beauty treatments, on-site laundry and dry cleaning and room service any time day or night.