5 Stars Hotels in Panama City
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Panama City 5 Star Hotels
Top Panama City 5 Star Hotels

Hotel Riu Plaza Panama
Bella Vista
9.0 out of 10, Wonderful, (4623)
The price is ฿3,675
฿4,042 total
includes taxes & fees
3 Dec - 4 Dec

Waldorf Astoria Panama
Bella Vista
9.0 out of 10, Wonderful, (1010)
The price is ฿5,766
฿6,343 total
includes taxes & fees
15 Dec - 16 Dec

W Panama
Bella Vista
9.0 out of 10, Wonderful, (1007)
The price is ฿5,977
฿6,575 total
includes taxes & fees
6 Dec - 7 Dec

JW Marriott Panama
San Francisco
9.0 out of 10, Wonderful, (1012)
The price is ฿5,977
฿6,575 total
includes taxes & fees
14 Dec - 15 Dec

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
9.8 out of 10, Exceptional, (547)
The price is ฿14,305
฿15,736 total
includes taxes & fees
15 Dec - 16 Dec

Hilton Panama
Bella Vista
8.8 out of 10, Excellent, (1005)
The price is ฿5,977
฿6,575 total
includes taxes & fees
7 Dec - 8 Dec

The Westin Playa Bonita Panama
Veracruz
8.0 out of 10, Very good, (1010)
The price is ฿5,158
฿5,674 total
includes taxes & fees
14 Dec - 15 Dec

Renaissance Panama City Hotel
Bella Vista
8.8 out of 10, Excellent, (93)
The price is ฿3,521
฿3,873 total
includes taxes & fees
5 Dec - 6 Dec
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.

Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is ฿3,442 per night from 8 Dec to 9 Dec
฿3,442
฿4,316 total
8 Dec - 9 Dec
includes taxes & fees
8.4/10 Very Good! (2,298 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Panama City
The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama
10/10 Excellent

Waldorf Astoria Panama
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
Hotels in Panama City by Star Rating
Accommodation near Panama City attractions
Choose Your Panama City Hotel Style
- Beach Resorts & Hotels in Panama City
- Business Hotels in Panama City
- Casino Hotels in Panama City
- Cheap Hotels in Panama City
- Family-Friendly Hotels in Panama City
- Historic Hotels in Panama City
- Hotels near Museums in Panama City
- Hotels with Air Conditioning in Panama City
- Hotels with Airport Transfers in Panama City
- Hotels with Babysitting Services in Panama City
- Hotels with Balcony in Panama City
- Hotels with Breakfast in Panama City
- Hotels with Connecting Rooms in Panama City
- Hotels with Entertainment in Panama City
- Hotels with Gym in Panama City
- Hotels with Hot Tubs in Panama City
- Hotels with Laundry Service in Panama City
- Hotels with Parking in Panama City
- Hotels with Parking in Panama City
- Hotels with Pool in Panama City
- Hotels with Restaurant in Panama City
- Hotels with Room Service in Panama City
- Hotels with Wifi in Panama City
- Hotels with a Bar in Panama City
- Hotels with a View in Panama City
- Hotels with smoking rooms in Panama City
- Luxury Hotels in Panama City
- Pet-Friendly Hotels in Panama City
- Shopping Hotels in Panama City
- Spa Hotels in Panama City
- Sports Hotels in Panama City
- Wedding Hotels in Panama City
More accommodation types in Panama City
Expedia's Latest Trends
Hotels
- The Myst Dong Khoi
- Hotels near Khao Khitchakut National Park
- Arawan Beach Resort Krabi
- Narita Tobu Hotel Airport
- Diamond Crown Hotel Patong
- Sukhothai Treasure Resort & Spa - SHA Plus
- Belle Villa Resort Khao Yai
- Ramada by Wyndham Aonang Krabi
- Hotels in Bang Saphan Noi
- LEK Jomtien Hotel
- Beach Resorts & Hotels in Phuket
- Sabai Sabai @ Sukhumvit Hotel
- CHERN Bangkok
Flights
Activities
Packages










































