5 Stars Hotels in Panama City

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Panama City 5 Star Hotels

This weekend
5 Jun - 7 Jun
Next weekend
12 Jun - 14 Jun

Our top choices for Panama City 5-star hotels

Outdoor pool, pool loungers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,527 reviews)
"Great place to stay. Staff are friendly and helpful."
United States
Gilbert
The price is ฿4,518
฿4,970 total
includes taxes & fees
29 Jun - 30 Jun
Hotel Riu Plaza Panama
2 bars/lounges, poolside bar

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,004 reviews)
"yes, nice breakfast"
United States
Fernando
The price is ฿8,261
฿9,087 total
includes taxes & fees
19 Jun - 20 Jun
Waldorf Astoria Panama
Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down duvets, pillow-top beds, minibar

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (659 reviews)
"Wonderful stay!!"
United States
Vesna
The price is ฿10,092
฿11,102 total
includes taxes & fees
2 Jul - 3 Jul
Sofitel Legend Casco Viejo, Panama City
4 outdoor pools, free pool cabanas, pool umbrellas

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,005 reviews)
"Amazing hotel!!!! 100% recommend!"
United States
Maria
The price is ฿8,035
฿8,838 total
includes taxes & fees
19 Jun - 20 Jun
JW Marriott Panama
Outdoor pool, pool umbrellas

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (323 reviews)
"Well run hotel, clean modern rooms, good food, amazing staff!"
Canada
Jesse
The price is ฿6,176
฿6,793 total
includes taxes & fees
18 Jun - 19 Jun
Hyatt Regency Panama City
Restaurant

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,008 reviews)
"Good stay, highly recommended "
United States
Chappel
The price is ฿8,094
฿8,903 total
includes taxes & fees
5 Jun - 6 Jun
W Panama
3 outdoor pools, pool umbrellas, pool loungers

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1,002 reviews)
"This is an excellent hotel and would highly recommend."
United States
Shernon
The price is ฿6,114
฿6,725 total
includes taxes & fees
26 Jun - 27 Jun
The Westin Playa Bonita Panama
Outdoor pool

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,005 reviews)
"Excelent hotel, great staff, amazing food, safe area"
United States
Ana
The price is ฿7,432
฿8,175 total
includes taxes & fees
8 Jun - 9 Jun
Hilton Panama
View from property

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (700 reviews)
"Breakfast was exceptional, everything you could think of was available. The spa was great and the staff 10/10"
United States
Aeon
The price is ฿7,777
฿8,554 total
includes taxes & fees
12 Jun - 13 Jun
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (222 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is ฿4,128
฿4,541 total
includes taxes & fees
8 Jun - 9 Jun
Renaissance Panama City Hotel
Couples treatment room(s), sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1,001 reviews)
"Perfect stay.. one of the best hotels we have stayed in ... no complaints"
United States
sydney McDonald
The price is ฿7,476
฿8,224 total
includes taxes & fees
26 Jun - 27 Jun
Bristol Panama, a Registry Collection Hotel
Lobby

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1,000 reviews)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
View from property

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very good, (1,000 reviews)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
The price is ฿4,128 per night from 30 Jun to 1 Jul
฿4,128
฿4,755 total
30 Jun - 1 Jul
includes taxes & fees
8.6/10 Excellent! (2,569 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
Evening skyline of Panama City

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

4/10 Poor
"The air conditioning in the room was ineffective and did not cool properly. There was also a leak outside my room that created a very unpleasant odor. Overall, the experience was disappointing.”"
aldrey 1-night trip
Posted less than an hour ago
Hotel Riu Plaza Panama

Frequently asked questions

What are the best 5-star hotels in Panama City?
According to Expedia guest reviews, Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are among the top 5-star hotels in Panama City. Providing top-quality amenities and unmatchable service, you'll enjoy a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in Panama City?
How much you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to stay, among other factors. Take advantage of our price per night filter and other search tools to find the best deal on a luxurious getaway.

  • Search for the lowest price per night from ฿3,057

What makes a hotel 5 stars in Panama City?
From fine dining restaurants and 24-hour gyms to swimming pools and the finest bedding, the 5-star experience in Panama City is all about comfort and luxury. But it takes more than just top-notch amenities to receive a 5-star rating. Hotels also have to offer remarkable guest-centric services like in-room beauty treatments, on-site laundry and dry cleaning and room service any time day or night.