A large, historic building with columns and a red facade, featuring flags and a sign indicating a separation of ways.

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Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

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Our top choices for Zona Ospedaliera hotels

A garden with a fountain, palm trees, and a fence.

1. HOTEL FEDERICO II

HOTEL FEDERICO II
3.0 star property
Zona Ospedaliera
7.4 out of 10, Good, (158 reviews)
"An older hotel but the room was clean, the bathroom was fine. Breakfast was good and the staff very helpful. I would stay there again."
Australia
Sue Anne
The price is ฿2,650
฿3,328 total
includes taxes & fees
3 Nov - 4 Nov
HOTEL FEDERICO II
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

2. Pansini Ruggiero's Apartaments

Pansini Ruggiero's Apartaments
Zona Ospedaliera
The price is ฿3,847
฿5,809 total
includes taxes & fees
29 Oct - 30 Oct
Pansini Ruggiero's Apartaments
The entrance of A Palazzo Argentina Hotel with a grand archway, potted plants, and a view of the street.

3. Hotel Palazzo Argenta

Hotel Palazzo Argenta
3.0 star property
4.7 km from Zona Ospedaliera
8.6 out of 10, Excellent, (547 reviews)
"Nice hotel near airport"
Canada
Tonny
The price is ฿1,723
฿2,308 total
includes taxes & fees
4 Nov - 5 Nov
Hotel Palazzo Argenta
A modern interior with a glass door leading to a sauna area, a decorative light fixture, and a small green plant.

4. LHP Napoli Palace & spa

LHP Napoli Palace & spa
5.0 star property
Fuorigrotta, 5 km from Zona Ospedaliera
9.0 out of 10, Wonderful, (162 reviews)
"Very clean and friendly."
United Kingdom
Mylvaganam
The price is ฿5,310
฿6,291 total
includes taxes & fees
10 Nov - 11 Nov
LHP Napoli Palace & spa
A modern outdoor deck with seating, a hot tub, and a view of the ocean.

5. Hotel & Resort Tre Fontane Luxury

Hotel & Resort Tre Fontane Luxury
10.9 km from Zona Ospedaliera
9.4 out of 10, Exceptional, (495 reviews)
"We enjoyed the hotel very much . Wonderful pool, bar , restaurant . Great location . Staff were so helpful!"
United States
Anthony
The price is ฿3,278
฿3,605 total
includes taxes & fees
6 Nov - 7 Nov
Hotel & Resort Tre Fontane Luxury
A modern hotel room with a large bed, bedside tables, a desk, and a chair.

6. Hotel Matilde - Lifestyle Hotel

Hotel Matilde - Lifestyle Hotel
4.0 star property
San Ferdinando, 4.7 km from Zona Ospedaliera
9.4 out of 10, Exceptional, (1,002 reviews)
"Great location, noisy, good service, good breakfast"
United States
shaull
The price is ฿4,410
฿5,301 total
includes taxes & fees
10 Nov - 11 Nov
Hotel Matilde - Lifestyle Hotel
The exterior of the Royal Continental Hotel with a prominent entrance, large glass doors, and potted plants.

7. Royal Continental Hotel Naples

Royal Continental Hotel Naples
4.0 star property
San Ferdinando, 5.3 km from Zona Ospedaliera
8.6 out of 10, Excellent, (1,477 reviews)
"Fine hotel and nice staff."
United States
Berardo
The price is ฿5,053
฿6,009 total
includes taxes & fees
8 Nov - 9 Nov
Royal Continental Hotel Naples
A multi-story hotel with a classic European architectural style, featuring balconies and a central entrance.

8. Grand Hotel Parkers

Grand Hotel Parkers
5.0 star property
Vittorio Emanuele, 3.9 km from Zona Ospedaliera
8.8 out of 10, Excellent, (924 reviews)
"Amazing hotel Very nice people and very helpful I’ll definitely recommend"
United States
shlomi
The price is ฿17,336
฿19,520 total
includes taxes & fees
8 Nov - 9 Nov
Grand Hotel Parkers
An outdoor dining area with tables set for a meal, overlooking a body of water and a distant shoreline.

9. Grand Hotel Vesuvio

Grand Hotel Vesuvio
5.0 star property
San Ferdinando, 5.4 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (734 reviews)
"Good hotel, walkable and plenty of nearby restaurants, bars, shopping and sites to see."
United States
Warren
The price is ฿16,900
฿19,041 total
includes taxes & fees
28 Oct - 29 Oct
Grand Hotel Vesuvio
A hotel entrance with a sign reading "HOTEL TIEMPO," surrounded by a landscaped garden with rocks, flowers, and a large planter.

10. Hotel Tiempo

Hotel Tiempo
3.0 star property
6.7 km from Zona Ospedaliera
8.0 out of 10, Very good, (846 reviews)
"10/10 place for the price. Breakfast was amazing, rooms were very clean. Best place to stay in Naples"
United States
Caleb William
The price is ฿2,298
฿2,941 total
includes taxes & fees
2 Nov - 3 Nov
Hotel Tiempo
An outdoor patio with white furniture, beige umbrellas, and a view of the sea.

11. Eurostars Hotel Excelsior

Eurostars Hotel Excelsior
4.0 star property
Santa Lucia, 5.4 km from Zona Ospedaliera
9.0 out of 10, Wonderful, (1,002 reviews)
"Fabulous stay ! Breakfast and service was amazing."
Canada
Harbir
The price is ฿5,813
฿6,845 total
includes taxes & fees
9 Nov - 10 Nov
Eurostars Hotel Excelsior
A modern lobby with a reception desk, glass railings, and a staircase.

12. CX Naples Centrale

CX Naples Centrale
Naples City Centre, 5.6 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (252 reviews)
"A central hotel, with good facilities and not too expensive. Breakfast was good if you need some fuel before exploring"
United Kingdom
David
The price is ฿2,592
฿3,266 total
includes taxes & fees
2 Nov - 3 Nov
CX Naples Centrale
The exterior of the Hotel Cristina with a modern entrance, glass doors, and a sign above the entrance.

13. Hotel Cristina

Hotel Cristina
3.0 star property
Fuorigrotta, 6 km from Zona Ospedaliera
9.0 out of 10, Wonderful, (615 reviews)
"Staff was very helpful with taxis, restaurant suggestions. A nice clean hotel."
Canada
Norm
The price is ฿3,349
฿4,097 total
includes taxes & fees
10 Nov - 11 Nov
Hotel Cristina
A hot tub on a balcony with a view of a hill and a historic building.

14. La Ciliegina Lifestyle Hotel

La Ciliegina Lifestyle Hotel
4.0 star property
Naples City Centre, 4.6 km from Zona Ospedaliera
9.4 out of 10, Exceptional, (730 reviews)
"Great location in a safe area! The hotel it’s super clean and the staff very helpful"
United States
karla
The price is ฿6,173
฿7,243 total
includes taxes & fees
2 Nov - 3 Nov
La Ciliegina Lifestyle Hotel
A dining table set with plates of food, glasses, and a bottle of wine.

15. Hotel Palazzo Esedra

Hotel Palazzo Esedra
4.0 star property
Fuorigrotta, 5.3 km from Zona Ospedaliera
8.6 out of 10, Excellent, (463 reviews)
"Old fittings; flush does not work; aircon switch does not work Minimum amenities"
Australia
Md Mazharul
The price is ฿4,435
฿5,331 total
includes taxes & fees
1 Nov - 2 Nov
Hotel Palazzo Esedra
A hotel room with a large bed, a desk, a chair, a TV, and a window with a city view.

16. Exe Majestic

Exe Majestic
4.0 star property
Chiaia, 4.3 km from Zona Ospedaliera
8.4 out of 10, Very good, (1,001 reviews)
"Great location for restaurants, shopping and site seeing"
United States
Cynthia
The price is ฿2,468
฿3,165 total
includes taxes & fees
10 Nov - 11 Nov
Exe Majestic
A hotel with a modern design, featuring a prominent 'Honda' sign on the top building. The hotel has multiple floors with large windows and a well-lit facade.

17. Holiday Inn Naples by IHG

Holiday Inn Naples by IHG
4.0 star property
6.2 km from Zona Ospedaliera
8.2 out of 10, Very good, (1,017 reviews)
"We truly enjoyed our stay"
United States
Quentin Vernon
The price is ฿2,492
฿3,568 total
includes taxes & fees
7 Nov - 8 Nov
Holiday Inn Naples by IHG
An outdoor patio area with tables and chairs, surrounded by potted plants and umbrellas.

18. Magris Hotel

Magris Hotel
4.0 star property
6.7 km from Zona Ospedaliera
8.2 out of 10, Very good, (796 reviews)
"I had an amazing stay at this hotel! Everything exceeded my expectations. The staff was incredibly friendly and attentive, making me feel welcome from the moment I arrived. The room was spotless, comfortable, and beautifully maintained. Also, a good breakfast selection. Highly recommend"
United States
Jude
The price is ฿3,831
฿4,664 total
includes taxes & fees
10 Nov - 11 Nov
Magris Hotel
An opulent room with ornate ceiling and walls, a patterned floor, and a dining area with tables and chairs.

19. Decumani Hotel De Charme

Decumani Hotel De Charme
4.0 star property
Porto, 4.4 km from Zona Ospedaliera
8.6 out of 10, Excellent, (1,002 reviews)
"Charming hotel. Awesome location. The staff was amazing. We’d stay again."
United States
Kristina
The price is ฿4,148
฿5,014 total
includes taxes & fees
2 Nov - 3 Nov
Decumani Hotel De Charme
A multi-story hotel with a classic architectural style, featuring balconies and a prominent entrance.

20. UNA Hotels Napoli

UNA Hotels Napoli
4.0 star property
Pendino, 5 km from Zona Ospedaliera
8.8 out of 10, Excellent, (1,006 reviews)
"Wonderful stay in the middle of everything You can get food & great coffee souvenirs all within a few shorts minutes walking distance"
United States
Lizzette
The price is ฿4,290
฿5,172 total
includes taxes & fees
1 Nov - 2 Nov
UNA Hotels Napoli
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Zona Ospedaliera

Find the best Zona Ospedaliera areas for the activities you enjoy most.
A grand building with a large dome and columns, likely a historical or religious site.

Naples City Centre

Known for its abundant dining options and interesting museums, there's plenty to explore in Naples City Centre. Top attractions like Port of Naples and Molo Beverello Port are major draws, and you can catch the metro at Garibaldi Tram Stop or EAV - Capolinea Porta Nolana Tram Stop to see more of the city.

A historic building with a large dome and columns.

Historical Center

Port of Naples and Via Toledo are top sights in Historical Center, and you should be sure to explore the popular shops. Hop aboard the metro at Toledo Station or Municipio Station to see more sights in the area.

A marina with various boats, a prominent castle, and a mountain in the background.

Chiaia

Mingle with the locals in the historic park, explore the little aquarium or gaze out to sea from this stylish part of the Italian city of “Napoli.”

A large domed building with columns and statues, surrounded by historic buildings.
Photo by pietro scerrato
Open Photo by pietro scerrato

San Ferdinando

If you're spending time in San Ferdinando, check out sights like Via Toledo or Molo Beverello Port and hop on the metro to see more of the city at Chiaia - Monte di Dio Station or Municipio Station.

A historic monument with intricate carvings and statues, surrounded by classical architecture and a clear blue sky.
Photo by Wolfgang Moroder
Open Photo by Wolfgang Moroder

Decumani

While you're in Decumani, take in top sights like Via San Gregorio Armeno and jump on the metro at Dante Station to see more of the city.

Top Zona Ospedaliera Hotel Reviews

Starhotels Terminus

Starhotels Terminus

10/10 Excellent
"Wonderful hotel room. Large room with large bath and walk-in shower. Room was clean and had good amenities. My one complaint would be that there was enough room for a larger chair to relax (and that would have been nice)"
Ernest 2-night trip
Posted less than an hour ago
Starhotels Terminus

Frequently asked questions

What's it like in Zona Ospedaliera?
Zona Ospedaliera is a neighbourhood that travellers like for its restaurants.
Where is the best place to stay in Zona Ospedaliera?
Based on Expedia customer reviews, HOTEL FEDERICO II is the highest ranked property in Zona Ospedaliera. This hotel offers a restaurant and free parking.
How many hotels should I expect to find in the Zona Ospedaliera area?
Book one of Expedia's 6 hotels and other accommodation options in Zona Ospedaliera and start exploring everything Naples has to offer.
If I need to cancel my hotel reservation in Zona Ospedaliera, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals in Zona Ospedaliera.
What is there to do around this Naples neighbourhood?
Via Toledo, Teatro Il Primo and Parco Urbano dei Camaldoli are just a few of the places to visit in and around Zona Ospedaliera. While you're out sightseeing, Sacra Ruota degli Esposti and Basilica SS Annunziata are a couple of additional sights to visit in Naples.
How can I get around Zona Ospedaliera and the greater Naples area?
Ready to get out and explore the city? Policlinico Station is the closest metro station.