Downtown Clayton Travel Guide
St. Louis
Visit Downtown Clayton
Things to do
StL's Signature "Sights and Bites" - Private Tour in St. Louis
฿5,740
per adult
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
฿492
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
฿787
per adult
100% of travellers recommend
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room
฿1,968
per adult
St. Louis: Museum of Illusions Entry Ticket
฿1,148
per adult
90% of travellers recommend
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
฿557
per traveller
Top hotels in Downtown Clayton
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is ฿3,473 per night from 18 Oct to 19 Oct
฿3,473
฿4,055 total
18 Oct - 19 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,431 reviews)
"An older, historic-looking hotel with character in a nice, walkable, safe area. I loved that my room was very well insulated and actually sound-proof from most street noise or human sounds inside the building. The furniture was old, with some looking original to the building. The breakfast was the ..."
Reviewed on 22 Sept 2026
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
The price is ฿4,268 per night from 4 Oct to 5 Oct
฿4,268
฿4,982 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ...
9.2/10 Wonderful! (403 reviews)
"No complaints"
Reviewed on 19 Sept 2026
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
The price is ฿5,057 per night from 4 Oct to 5 Oct
฿5,057
฿5,954 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿4,756 per night from 3 Oct to 4 Oct
฿4,756
฿5,609 total
3 Oct - 4 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
The price is ฿2,991 per night from 27 Sept to 28 Sept
฿2,991
฿3,522 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (3,246 reviews)
"Excellent front desk staff,very friendly and helpful..We arrived in time for free evening snacks and drinks..Room was very comfortable and roomy..Airport shuttle is a added plus, we used long term parking for our trip and it was very convenient, the shuttle delivered us right to our car on return..highly ..."
Reviewed on 22 Sept 2026
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿3,927 per night from 11 Oct to 12 Oct
฿3,927
฿4,594 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very good! (1,184 reviews)
"This was a great place with a welcoming atmosphere. The staff were outstanding—friendly, attentive, and professional—making the experience even more enjoyable. The people there were remarkable, contributing to a lively and positive environment."
Reviewed on 22 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Downtown Clayton hotel availability
Where to stay in Downtown Clayton
Find the best Downtown Clayton areas for the activities you enjoy most.
Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch National Park to Kiener Plaza – discover Downtown St. Louis, a destination also famous for its historic sites.
Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.
Central West End
The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.
St. Charles Historic District
St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.
Creve Coeur
Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
