Downtown Clayton Travel Guide

St. Louis

A bronze bell with an eagle atop, surrounded by greenery and a street scene in the background.

Things to do

The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

฿5,843
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
Self Guided Walking & Driving Audio Tour St. Louis

Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP

฿500
per traveller
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour

St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour

฿567
per traveller
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

฿801
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room

St. Louis Burlesque & Nightlife Experience at The Boom Boom Room

฿2,003
per adult
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room
St. Louis: Museum of Illusions Entry Ticket

St. Louis: Museum of Illusions Entry Ticket

฿1,169
per adult
90% of travellers recommend
St. Louis: Museum of Illusions Entry Ticket
See all activities in St. Louis

Top hotels in Downtown Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ฿3,106 per night from 1 Nov to 2 Nov
฿3,106
฿3,626 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
9/10 Wonderful! (3,496 reviews)
"Loud central air couldn’t sleep all night."

Reviewed on 21 Oct 2026

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is ฿5,110 per night from 1 Nov to 2 Nov
฿5,110
฿6,016 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
8.8/10 Excellent! (794 reviews)
"Hairs in the shower and sucks that you have to pay for WiFi"

Reviewed on 20 Oct 2026

Le Méridien St. Louis Clayton
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

2 out of 5
227 South Central Ave St. Louis MO
The price is ฿4,312 per night from 25 Oct to 26 Oct
฿4,312
฿5,034 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ...
9.2/10 Wonderful! (417 reviews)
"This property's strength is its people. Otherwise, totally unremarkable. The rooms are small and of no character whatsoever."

Reviewed on 20 Oct 2026

AC Hotel St. Louis Clayton
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
The price is ฿3,022 per night from 25 Oct to 26 Oct
฿3,022
฿3,589 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is ฿4,534 per night from 25 Oct to 26 Oct
฿4,534
฿5,301 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,809 reviews)
"."

Reviewed on 21 Oct 2026

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is ฿4,504 per night from 31 Oct to 1 Nov
฿4,504
฿5,311 total
31 Oct - 1 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,361 reviews)
"We stayed there on September 19, 2026 and it is now October 20, 2026. They overcharged me almost $350 and blamed it on hotels.com. Hotels has gone to bat for me trying to get the overcharge returned. So far no luck on my refund."

Reviewed on 20 Oct 2026

Hyatt Regency St. Louis at The Arch
See all 1,943 properties in Downtown Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Downtown Clayton Travel Guide