Downtown Clayton Travel Guide
St. Louis
Visit Downtown Clayton
Things to do
StL's Signature "Sights and Bites" - Private Tour in St. Louis
฿5,740
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
฿787
per adult
100% of travellers recommend
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room
฿1,968
per adult
St. Louis: Museum of Illusions Entry Ticket
฿1,148
per adult
90% of travellers recommend
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
฿557
per traveller
Downtown St. Louis Smartphone Guided Audio Walking Tour App
฿254
per adult
100% of travellers recommend
Top hotels in Downtown Clayton
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is ฿3,113 per night from 11 Oct to 12 Oct
฿3,113
฿3,634 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,402 reviews)
"Had a great stay at Clayton Plaza Hotel! The property was very clean, and our room was well maintained and comfortable. What really stood out was the staff. Everyone was extremely attentive, friendly, and helpful throughout our stay. They genuinely went above and beyond to make sure we were taken ..."
Reviewed on 14 Sept 2026
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
The price is ฿4,016 per night from 27 Sept to 28 Sept
฿4,016
฿4,688 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ...
9.2/10 Wonderful! (398 reviews)
"Awesome hotel I would stay there again"
Reviewed on 13 Sept 2026
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
The price is ฿5,029 per night from 4 Oct to 5 Oct
฿5,029
฿5,921 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
8.8/10 Excellent! (775 reviews)
"If I could give this hotel 10 stars I would. Staff was amazing, food was incredible, and all areas were clean and well maintained. Shout out to the woman who was attending the pool who was a rockstar handling a lot of people, bartending, and taking food orders all with a smile."
Reviewed on 13 Sept 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿5,027 per night from 4 Oct to 5 Oct
฿5,027
฿5,928 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,279 reviews)
"We were there for a concert and the hotel took full advantage of that fact and charged you for everything that they could. Super disappointed. They would only let you valet your car, no self park. They had you by the balls and they knew it. Otherwise, it was just a room, nothing special."
Reviewed on 14 Sept 2026
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
The price is ฿2,974 per night from 20 Sept to 21 Sept
฿2,974
฿3,502 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
The price is ฿4,072 per night from 2 Oct to 3 Oct
฿4,072
฿4,763 total
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very good! (1,176 reviews)
"The staff is so nice!"
Reviewed on 13 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Downtown Clayton hotel availability
Where to stay in Downtown Clayton
Find the best Downtown Clayton areas for the activities you enjoy most.
Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.
Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.
Central West End
The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Creve Coeur
Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
St. Charles Historic District
St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.
