The Best Hotels in Santissima Annunziata, Florence - 2026 Updated Prices

A statue of a man on horseback in a public square with people and bicycles around.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Compare popular hotels in Santissima Annunziata

Property	Property class	Guest rating
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World	5.0 star property	10.0 Exceptional 24 reviews	View
Hotel Firenze Capitale	3.0 star property	9.6 Exceptional 61 reviews	View
Loggiato dei Serviti	3.0 star property	9.6 Exceptional 530 reviews	View
Alfieri9	3.0 star property	9.6 Exceptional 170 reviews	View
Hotel Regency	5.0 star property	9.4 Exceptional 459 reviews	View

Where to stay in Santissima Annunziata

Find the best Santissima Annunziata areas for the activities you enjoy most.

A river with buildings on the right bank.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

See properties

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

See properties

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

See properties

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

See properties

An ornate building with intricate architectural details and a clear blue sky in the background.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

See properties

Top Santissima Annunziata Hotel Reviews

a&o Hostel Firenze Campo Di Marte

10/10 Excellent

"Excellent place to stay. Staffs are friendly and they even speak good English. They go out of their way to help and guide you. The place was clean and well kept. Location of the property excellent - right opposite to the station . That has easy access to main Florence station."

B&B Cherubini 13

8/10 Good

"Overall we had a good experience in Cherubini 13, with some issues that prevented it being perfect. Our room in Cherubini was comfortable and beautiful with a lovely balcony, the apartment was well located in a gorgeous old building (not too central and noisy but not too far away) and it came at a reasonable price. However, instructions for checking in were not clear. We had to message the management when we arrived to be remotely let into the building, but ended up waiting over 40 minutes without reply before being let in by other guests. We had no actual contact with the management other than messaging to try and let us in, and them telling us we had to leave cash in the room to pay the city tax (which was fine, but could have been handled better). There was also some confusion over which facilities were available to us, with no clear indication if we could use the kitchen and coffee machine. The hotel should really not be called a B&B, as the experience was much more like using an AirB&B shared by multiple guests. All rooms were lockable and our room had an en suite, so this didnt bother us, but if you're expecting a traditional hotel it isn't that. Overall our experience was very pleasant and these negatives were outweighed by the positives (clean, good location, and a beautiful room), but the delay in accessing the property causes unnecessary stress."

Hotel Astro Mediceo

8/10 Good

"Very nice property, lovely staff. Super convenient location if you have a car. An easy walk into the center, and an easy exit from town. Dont miss mercato in Piazza Cure, just on the other side of the train tracks. 4 stars because the beds were classically terrible, hard italian mattresses with equally flat pillows and because despite a request, our mini fridge didnt work. Also, their parking lot behind the property is quite small and you need to call ahead to ensure they save you a spot. The staff were ULTRA helpful and managed to wedge us in and back us out as well. I would consider staying here again...esp if the bedding were improved. :)"

Hotel Le Due Fontane

10/10 Excellent

"My wife broke her leg in Florence and was put into a cast by the hospital. The staff at this hotel was so helpful, trying to attend to her needs. They even gave us an additional room for free for my wife since our room did not have lift access, so we then occupied two rooms for the remainder of our stay (cut short, as we needed to go home early) I have to commend the compassion of each individual hotel staff member."

3110 ArtHotel

10/10 Excellent

"Cute, artsy boutique hotel in a quiet part of town, close to groceries and a few great restaurants. The bus stop is pretty much right outside the door, and the tram to the center and airport also just a few blocks away. Our room was spacious and clean, the AC worked well. The king size bed and sofa/twin bed was perfect for a couple and 12-year-old. The bathroom and shower in particular are a bit small, but perfectly fine. Good water pressure, and my husband loved the bidet! We also enjoyed the buffet breakfast with indoor and outdoor patio seating. The staff was helpful and friendly. Would definitely stay here again!"

Frequently asked questions

What's it like in Santissima Annunziata?

Santissima Annunziata is an historic neighbourhood known for its picturesque gardens and cycling. Make sure that you visit Statue of David and Gallery of the Academy of Florence as part of your Santissima Annunziata travel plans.

What's a favourite place to stay in Santissima Annunziata?

Based on our traveller data, Hotel Regency is one of the top choices for your stay in Santissima Annunziata. This hotel is a short 15-minute walk from Piazza del Duomo, and it offers free breakfast and a restaurant. Other good options for your stay in the area include Hotel Astro Mediceo and Four Seasons Hotel Firenze.

How many hotels will I be able to find in the Santissima Annunziata area?

If you're searching for places to stay in Florence, Expedia has something to meet your needs with 485 Santissima Annunziata hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Santissima Annunziata, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the top deals on offer in Santissima Annunziata.

What are the top things to see and do in Santissima Annunziata?

Attractions such as Gallery of the Academy of Florence, Museo degli Innocenti and Teatro Le Laudi highlight Florence's cultural scene. Statue of David and Piazza Donatello are also a couple of places to visit in the neighbourhood. Piazza del Duomo and Piazza di Santa Maria Novella are some popular places to visit in the area around Santissima Annunziata. English Cemetery and Palazzo Capponi are also worth a visit when you're out sightseeing in Florence.

How can I get around Santissima Annunziata and the greater Florence area?

If you're considering venturing out of town, train travel is a great option. Florence Campo di Marte Station is the closest train station, but Florence (FIR-Firenze Campo di Marte Rail Station) and Florence-Le Cure Station are also close by.

Explore a world of travel with Expedia

More ways to book

Book Hotels in Santissima Annunziata on Expedia.it

Search Hotels in Santissima Annunziata, Florence

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santissima Annunziata hotels

1. Four Seasons Hotel Firenze

2. Hotel Regency

3. Forte16 View & Spa

4. Hotel Villa Liana

5. Alfieri9

6. Loggiato dei Serviti

7. Hotel Meridiana

8. Hotel Villa Il Castagno

9. Pier Capponi 17 Room & Suites

10. Messori Suites

11. Numa Florence della Robbia

12. The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

13. Relais la Corte di Cloris

14. Guest House Morandi

15. De La Pace, Sure Hotel Collection by Best Western

16. Firenze Residence

17. Villa Tortorelli

18. Palazzo Lombardo

19. B&B Cherubini 13

20. Hotel Le Due Fontane

Compare popular hotels in Santissima Annunziata

Where to stay in Santissima Annunziata

Historic Centre of Florence

Duomo

San Giovanni

Santa Maria Novella

Santa Croce

Top Santissima Annunziata Hotel Reviews

a&o Hostel Firenze Campo Di Marte

Frequently asked questions

Explore a world of travel with Expedia