The Best Hotels in Santissima Annunziata, Florence - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Compare popular hotels in Santissima Annunziata

Property	Property class	Guest rating
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World	5.0 star property	10.0 Exceptional 20 reviews	View
Four Seasons Hotel Firenze	5.0 star property	9.8 Exceptional 307 reviews	View
Hotel Ungherese	3.0 star property	9.4 Exceptional 67 reviews	View
Loggiato dei Serviti	3.0 star property	9.6 Exceptional 505 reviews	View
Alfieri9	3.0 star property	9.6 Exceptional 167 reviews	View

Where to stay in Santissima Annunziata

Find the best Santissima Annunziata areas for the activities you enjoy most.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

See properties

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

See properties

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

See properties

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

See properties

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

See properties

Top Santissima Annunziata Hotel Reviews

Hotel Meridiana

10/10 Excellent

"Perfect"

B&B Cherubini 13

8/10 Good

"Nice room and a great location, close to the city center and museums, with easy access to the train station by bus or tram. The room was mostly clean, although we noticed dust under the beds when our child’s toy rolled underneath. Also, despite being a B&B, breakfast during our stay was limited to coffee and tea bags. Overall, a pleasant stay with room for improvement."

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

10/10 Excellent

"This property is stunning. Our room was comfortable, clean, and exquisitely designed. Our only complaint is that there is not food available midday. They have a room service menu, but they don’t actually have the items available outside of dinner time (even though the menu says otherwise). It was only an issue when we first arrived very tired, as there are plenty of food options close to the hotel."

Forte16 View & Spa

8/10 Good

"This hotel is located a little off the beaten path, but it offers convenient access to both the bus routes serving many of the area's top attractions and the train station, which was very helpful during our stay. The property is well maintained, and the rooms are spacious and comfortable. The rooftop area offers beautiful sunset views, while the pool and sauna were a nice added touch. One thing to note is that some of the photos may give the impression that the rooftop hot tub is available for general guest use. In reality, it is a private rental, so keep that in mind if that amenity is a deciding factor for your stay. The experience is a little more rugged and independent than a traditional hotel, but that was not a problem for us. Overall, we had no complaints and would happily stay here again."

Frequently asked questions

What's it like in Santissima Annunziata?

Santissima Annunziata is an historic neighbourhood known for its picturesque gardens and cycling. Make sure that you visit Piazza Massimo D'Azeglio and Statue of David as part of your Santissima Annunziata travel plans.

What's a favourite place to stay in Santissima Annunziata?

Based on our traveller data, Four Seasons Hotel Firenze is one of the top choices for your stay in Santissima Annunziata. This hotel is a short 14-minute walk from Cathedral of Santa Maria del Fiore, and it offers a full-service spa and 3 restaurants. Other good options for your stay in the area include Hotel Regency and Hotel Astro Mediceo.

How many hotels will I be able to find in the Santissima Annunziata area?

If you're searching for places to stay in Florence, Expedia has something to meet your needs with 489 Santissima Annunziata hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Santissima Annunziata, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the top deals on offer in Santissima Annunziata.

What are the top things to see and do in Santissima Annunziata?

Attractions such as Gallery of the Academy of Florence, Teatro Le Laudi and National Archaeological Museum highlight Florence's cultural scene. Piazza Massimo D'Azeglio and Statue of David are also a couple of places to visit in the neighbourhood. Don't miss favourite places to visit in the surrounding area, such as Cathedral of Santa Maria del Fiore, Uffizi Gallery and Piazza di Santa Maria Novella. English Cemetery and Piazza Donatello are also worth a visit when you're out sightseeing in Florence.

How can I get around Santissima Annunziata and the greater Florence area?

If you're considering venturing out of town, train travel is a great option. Florence Campo di Marte Station is the closest train station, but Florence (FIR-Firenze Campo di Marte Rail Station) and Florence-Le Cure Station are also close by.

Explore a world of travel with Expedia

More ways to book

Book Hotels in Santissima Annunziata on Expedia.it

Search Hotels in Santissima Annunziata, Florence

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Guest rating

Star rating

Our top choices for Santissima Annunziata hotels

B&B Cherubini 13

Four Seasons Hotel Firenze

Hotel Regency

Firenze Suite

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

Forte16 View & Spa

Alina Apartment by Mamo Florence

Numa Florence della Robbia

Hotel Ungherese

Loggiato dei Serviti

Palazzo Lombardo

Mamo Florence - Fiorenza Historical Apartment

a&o Hostel Firenze Campo Di Marte

Hotel Villa Il Castagno

Palazzo Alfani al David

Amalia Apartments - Via la Farina

Aura Suites Florence

Messori Suites

B&B Lorena Suites & Apartments

PALAZZO TESTA - LOCAZIONE TURISTICA

Compare popular hotels in Santissima Annunziata

Where to stay in Santissima Annunziata

Historic Centre of Florence

Duomo

San Giovanni

Santa Maria Novella

Santa Croce

Top Santissima Annunziata Hotel Reviews

Hotel Meridiana

Frequently asked questions

Explore a world of travel with Expedia