Matlacha Isles Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ฿4,531 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles

Top hotels in Matlacha Isles

Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ฿2,797 per night from 25 Jan to 26 Jan
฿2,797
฿3,118 total
25 Jan - 26 Jan
includes taxes & fees
6.6/10 (1,001 reviews)
Bien.

Reviewed on 19 Jan 2026

Baymont by Wyndham Fort Myers Central
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is ฿6,964 per night from 27 Jan to 28 Jan
฿6,964
฿8,458 total
27 Jan - 28 Jan
includes taxes & fees
9/10 Wonderful! (1,126 reviews)
Great svc rooftop bar

Reviewed on 18 Jan 2026

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
The price is ฿8,670 per night from 25 Jan to 26 Jan
฿8,670
฿10,444 total
25 Jan - 26 Jan
includes taxes & fees
9/10 Wonderful! (1,542 reviews)
We loved Sanibel Island Beach Resort. Staff was attentive, rooms were clean, and the property was beautiful. The direct access to he beach was a plus!

Reviewed on 19 Jan 2026

Sanibel Island Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Matlacha Isles holiday package cost?
Our Matlacha Isles holiday packages, which begin from just , are the best way to save loads of cash. Select your favourite flights, hotels and rental cars to create a custom-built itinerary.
How do I get a cheap travel package to Matlacha Isles?
Combine your hotel and flight bookings, add on extras such as activities, and save with a Matlacha Isles holiday package. You won't just walk away with awesome discounts on your trip — you'll have loads of choice at your fingertips too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 hotels around the globe. Your next epic adventure begins right here, right now!
Where should I stay in Matlacha Isles?
If you're itching to be where the action is, stay near Sun Splash Water Park. Many happy campers book a hotel around this renowned tourist attraction.
What are the top hotels in Matlacha Isles?
Reserve a room at The Perfect Day In Matlacha Direct Gulf Access. It's one of the neighbourhood's most popular hotels. Another highly rated option in Matlacha Isles is Fun'n Sun - Charming 3 Br/ 3 Baths Waterfront Villa W. Boat Lift.
How far in advance should I book my Matlacha Isles holiday?
Smart travellers will likely want to reserve their seats early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you've left things to the last minute, don't stress. Low prices occasionally become available just weeks prior to departure.
What does an Expedia Matlacha Isles travel package include?
Expedia has all you need to organise your Matlacha Isles trip, but how you structure your package depends on you. Select from a combination of rental cars, hotels and flights. Chasing some experiences or tours to keep you busy? Once you've made your booking, you can add them on too. No matter your budget, there's a deal to suit your needs.
What should I know before booking a Matlacha Isles travel package?
Bundling your bookings into a Matlacha Isles holiday package is the easiest way to organise your trip. Not only that, you'll save just for combining your hotels, flights and car rentals. Once you've booked, why not add on a day tour or an activity?
Can I choose my airline with a Matlacha Isles Expedia holiday package?
Yes, definitely. Expedia has more than 550 partner airlines to select from globally. With all that choice, finding the ideal carrier to bring you to Matlacha Isles will be easy.
If I'm not able to travel, can I cancel my Matlacha Isles holiday package?
Don't worry if you're rethinking your Matlacha Isles holiday package — you can cancel or change your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We get that your circumstances can suddenly change, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Popular places to visit

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.