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Our top choices for Matlacha Isles hotels

Seahorse Cottages on Sanibel - Adults Only
Seahorse Cottages on Sanibel - Adults Only21.2 km from Matlacha Isles
9.6 out of 10, Exceptional, (82 reviews)
The price is ฿6,261
฿6,981 total
includes taxes & fees
25 Jan - 26 Jan

Lani Kai Beachfront Resort
Lani Kai Beachfront Resort23.2 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,148 reviews)
The price is ฿7,016
฿8,521 total
includes taxes & fees
27 Jan - 28 Jan

Baymont by Wyndham Punta Gorda/Port Charlotte
Baymont by Wyndham Punta Gorda/Port Charlotte28.9 km from Matlacha Isles
8.4 out of 10, Very good, (1,167 reviews)
The price is ฿3,635
฿4,071 total
includes taxes & fees
25 Jan - 26 Jan

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park28 km from Matlacha Isles
8.0 out of 10, Very good, (1,551 reviews)
The price is ฿2,789
฿3,110 total
includes taxes & fees
25 Jan - 26 Jan

Comfort Inn & Suites Fort Myers Airport
Comfort Inn & Suites Fort Myers Airport27.9 km from Matlacha Isles
8.8 out of 10, Excellent, (1,116 reviews)
The price is ฿3,353
฿3,738 total
includes taxes & fees
25 Jan - 26 Jan

Woodspring Suites Fort Myers - Cape Coral
Woodspring Suites Fort Myers - Cape Coral18.2 km from Matlacha Isles
7.2 out of 10, Good, (168 reviews)
The price is ฿2,786
฿3,107 total
includes taxes & fees
24 Jan - 25 Jan

Comfort Suites Fort Myers East I-75
Comfort Suites Fort Myers East I-7524.8 km from Matlacha Isles
9.6 out of 10, Exceptional, (386 reviews)
The price is ฿4,231
฿4,718 total
includes taxes & fees
1 Feb - 2 Feb

Quality Inn Fort Myers Cape Coral
Quality Inn Fort Myers Cape Coral18.4 km from Matlacha Isles
7.6 out of 10, Good, (215 reviews)
The price is ฿2,634
฿3,406 total
includes taxes & fees
25 Jan - 26 Jan

Hampton Inn & Suites Fort Myers - Colonial Blvd
Hampton Inn & Suites Fort Myers - Colonial Blvd21 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,000 reviews)
The price is ฿4,492
฿5,009 total
includes taxes & fees
1 Feb - 2 Feb

Best Western Fort Myers Inn & Suites
Best Western Fort Myers Inn & Suites20.8 km from Matlacha Isles
8.8 out of 10, Excellent, (1,132 reviews)
The price is ฿3,297
฿3,676 total
includes taxes & fees
25 Jan - 26 Jan

Knights Inn Punta Gorda
Knights Inn Punta Gorda28.5 km from Matlacha Isles
7.2 out of 10, Good, (956 reviews)
The price is ฿2,850
฿3,192 total
includes taxes & fees
24 Jan - 25 Jan

Holiday Inn Express & Suites Fort Myers Airport by IHG
Holiday Inn Express & Suites Fort Myers Airport by IHG29 km from Matlacha Isles
9.6 out of 10, Exceptional, (1,003 reviews)
The price is ฿4,508
฿5,026 total
includes taxes & fees
25 Jan - 26 Jan

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach20.4 km from Matlacha Isles
8.8 out of 10, Excellent, (1,000 reviews)
The price is ฿4,931
฿5,498 total
includes taxes & fees
26 Jan - 27 Jan

Sanibel Island Beach Resort
Sanibel Island Beach Resort22.7 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,552 reviews)
The price is ฿8,734
฿10,521 total
includes taxes & fees
25 Jan - 26 Jan

Comfort Inn Fort Myers Northeast
Comfort Inn Fort Myers Northeast25.8 km from Matlacha Isles
7.8 out of 10, Good, (683 reviews)
The price is ฿3,852
฿4,295 total
includes taxes & fees
25 Jan - 26 Jan

Quality Suites Fort Myers I-75
Quality Suites Fort Myers I-7527.1 km from Matlacha Isles
8.2 out of 10, Very good, (1,002 reviews)
The price is ฿3,176
฿3,541 total
includes taxes & fees
25 Jan - 26 Jan

Travelodge by Wyndham Fort Myers Airport
Travelodge by Wyndham Fort Myers Airport27.1 km from Matlacha Isles
7.4 out of 10, Good, (1,003 reviews)
The price is ฿2,085
฿2,325 total
includes taxes & fees
25 Jan - 26 Jan

Hyatt Place Fort Myers/at The Forum
Hyatt Place Fort Myers/at The Forum24.7 km from Matlacha Isles
8.2 out of 10, Very good, (1,002 reviews)
The price is ฿4,508
฿5,026 total
includes taxes & fees
25 Jan - 26 Jan

Courtyard by Marriott Fort Myers Cape Coral
Courtyard by Marriott Fort Myers Cape Coral20.4 km from Matlacha Isles
8.2 out of 10, Very good, (1,000 reviews)
The price is ฿3,916
฿4,367 total
includes taxes & fees
1 Feb - 2 Feb

Boca Grande Hotel
Boca Grande Hotel28.8 km from Matlacha Isles
8.8 out of 10, Excellent, (592 reviews)
The price is ฿4,852
฿5,435 total
includes taxes & fees
26 Jan - 27 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.

Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Mariner
While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area.

Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Top Matlacha Isles Hotel Reviews

Lani Kai Beachfront Resort
10/10 Excellent









































































