A grand church interior with high vaulted ceilings, large columns, and a central altar.

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Our top choices for Santo Spirito hotels

1. Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (713 reviews)
"We had a wonderful stay - the property was beautiful, breakfast was great, and the staff were SO helpful and accommodating. I would recommend this hotel to anyone."
Canada
CHRISTINE
The price is ฿5,975
฿7,106 total
includes taxes & fees
24 Aug - 25 Aug
Hotel Horto Convento

2. UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze
4.0 star property
Santo Spirito
8.4 out of 10, Very good, (1,006 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"
United Kingdom
Glenn
The price is ฿2,809
฿3,624 total
includes taxes & fees
30 Aug - 31 Aug
UNA Hotels Vittoria Firenze

3. Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,159 reviews)
"We loved it!"
United States
Beatriz
The price is ฿4,028
฿4,965 total
includes taxes & fees
24 Aug - 25 Aug
Palazzo Mannaioni Suites

4. La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.2 out of 10, Wonderful, (296 reviews)
"Lovely residence-style building in a quieter neighborhood that is close to all you need."
Canada
Jayme
The price is ฿3,275
฿4,137 total
includes taxes & fees
26 Aug - 27 Aug
La Torre Del Cestello

5. Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (201 reviews)
"This was a quaint little hotel. It was has a really friendly vibe. It’s a bit dated, but it only adds to its charm. I would return to this hotel. "
United States
Martin
The price is ฿2,410
฿2,994 total
includes taxes & fees
2 Sept - 3 Sept
Hotel Firenze 2000

6. AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (238 reviews)
"A delight - the perfect escape from the hustle and bustle of Florence A great room full of character The terrace was perfect for breakfast and an early evening drink The staff were very helpful with great restaurant recommendations"
United Kingdom
Peter
The price is ฿10,925
฿12,552 total
includes taxes & fees
25 Aug - 26 Aug
AdAstra Suites

7. Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is ฿18,618
฿21,014 total
includes taxes & fees
23 Aug - 24 Aug
Torre di Bellosguardo

8. Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (176 reviews)
"Quaint boutique hotel in great location. Clean comfortable room and nice breakfast. Wonderful restaurant almost next door and close to train station. Highly recommend."
United States
Timothy
The price is ฿7,440
฿8,718 total
includes taxes & fees
6 Sept - 7 Sept
Ottantotto Firenze

9. Hotel Palazzo Guadagni

Hotel Palazzo Guadagni
3.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (212 reviews)
"Historic vibes, clean room, nice view, helpful staff. Breakfast was included and all you can eat. Food was fresh and coffee was good."
United States
Samuel
The price is ฿15,632
฿17,653 total
includes taxes & fees
21 Sept - 22 Sept
Hotel Palazzo Guadagni

10. 1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (203 reviews)
"We had an amazing stay at 1900 Artevita. Friendly staff and very convenient location with close bus stop and comfortable walk to city centre"
Canada
Miket
The price is ฿2,154
฿2,827 total
includes taxes & fees
23 Aug - 24 Aug
1900 Artevita

11. Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (136 reviews)
"Amazing location, charming hotel and great breakfast"
Sweden
Carin
The price is ฿8,272
฿9,634 total
includes taxes & fees
23 Aug - 24 Aug
Oltrarno Splendid

12. Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (380 reviews)
"Excellent location and wonderful staff in a unique building with an amazing history."
United Kingdom
Matthew
The price is ฿4,085
฿4,951 total
includes taxes & fees
24 Aug - 25 Aug
Casa Santo Nome di Gesù

13. La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (183 reviews)
"Really nice, handy location"
United Kingdom
Kate
The price is ฿3,376
฿4,171 total
includes taxes & fees
25 Aug - 26 Aug
La Fonderia Firenze

14. Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (152 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is ฿5,239
฿6,221 total
includes taxes & fees
31 Aug - 1 Sept
Drom Florence Rooms & Apartments

15. Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (44 reviews)
"We stayed with our children and the space was excellent and the location was close enough to walk to everything. "
United States
Juliet
The price is ฿2,517
฿6,279 total
includes taxes & fees
27 Aug - 28 Aug
Appartamenti degli Artisti by Mmega

16. Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (235 reviews)
"I had a lovely stay! Staff were helpful"
United States
Alloura
The price is ฿2,708
฿3,437 total
includes taxes & fees
31 Aug - 1 Sept
Foresteria Valdese di Firenze - Casa per Ferie

17. B&B Mia Palace

B&B Mia Palace
Santo Spirito
8.4 out of 10, Very good, (123 reviews)
"Breakfast was excellent and what a lovely host. "
United Kingdom
Wayne
The price is ฿2,773
฿3,508 total
includes taxes & fees
25 Aug - 26 Aug
B&B Mia Palace

18. Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (106 reviews)
"I really enjoyed my stay here. The host was also extremely kind and helpful."
Belgium
Mary Mariam
The price is ฿2,381
฿3,077 total
includes taxes & fees
23 Aug - 24 Aug
Palazzo Oliveto

19. SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (26 reviews)
"Easy check in and very helpful and polite "
United States
Remi
The price is ฿7,367
฿8,561 total
includes taxes & fees
23 Aug - 24 Aug
SPIRIT OF FLORENCE Boutique Rooms

20. Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (168 reviews)
"Excellent place"
United States
Laura Patricia
The price is ฿3,807
฿4,722 total
includes taxes & fees
26 Aug - 27 Aug
Residenza D'Epoca Al Numero 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Vibrant Piazza Santo Spirito: Experience the lively atmosphere of this bustling square, surrounded by trendy cafes and artisan shops.
  • Historic San Spirito Church: Explore this beautiful church, which showcases remarkable Renaissance architecture and art.
  • Local Market Experience: Immerse yourself in local life at the lively public market, perfect for tasting authentic Tuscan delicacies.
  • Tuscan Wine Tours: Indulge in exquisite wine tours to savour the renowned flavours of Tuscany.
  • Charming Accommodations: Choose from a delightful array of bed and breakfasts and elegant hotels for a memorable stay.

Find great hotels near Santo Spirito

In the heart of Santo Spirito, Florence, you'll discover a delightful selection of accommodations, ranging from charming bed and breakfasts to elegant hotels. This vibrant area offers a unique blend of city-themed experiences, antique furnishings, and pet-friendly options. Whether you're drawn to the historic allure of Palazzo Ridolfi or the artistic charm near Santa Croce, you'll find the perfect base for your Tuscan adventure.

  • The Social Hub Florence Lavagnini: This vibrant 4-star hotel offers a modern and stylish retreat, ideal for those seeking both adventure and business amenities. Located 2km from Santo Spirito, The Social Hub Florence Lavagnini is designed for the contemporary traveller. The property features a range of adventure sports and recreational activities both onsite and in the surrounding area, making it an excellent choice for exploring Florence. Guests can enjoy a lively atmosphere complemented by comfortable accommodations, ensuring a memorable stay.
  • B&B Hotel Firenze Pitti Palace al Ponte Vecchio: Situated 1km from Santo Spirito, this charming 4-star hotel is perfect for families and adventure seekers alike. The B&B Hotel Firenze Pitti Palace al Ponte Vecchio offers various activities, including nearby bicycle rentals for those eager to explore the scenic surroundings. Families will appreciate the dedicated amenities for children, including babysitting and childcare services available onsite, making it a convenient choice for parents travelling with little ones.
  • Grand Hotel Cavour: Located 2km from Santo Spirito, the Grand Hotel Cavour is a refined choice for families and pet owners. This 4-star establishment boasts a welcoming atmosphere with services tailored for children, such as in-room and onsite babysitting options. Additionally, the hotel accommodates pets, allowing furry companions to join in on the adventure. Guests can expect an elegant stay with amenities that cater to both relaxation and family needs, creating a home-away-from-home experience in the heart of Florence.

Where to stay near Santo Spirito

Discover the vibrant charm of Santo Spirito in Florence, where the heart of the Florentine Renaissance comes alive. Stroll through the lively Piazza Santo Spirito, surrounded by trendy cafes and artisan shops, perfect for soaking up the local atmosphere. This neighbourhood offers a unique blend of history and modernity, creating a welcoming space for relaxation and exploration. Venture nearby to experience the romantic streets and secluded corners that make Tuscany truly enchanting.

  • Florence: As the heart of Tuscany, Florence is a vibrant city brimming with culture and history. Nestled along the banks of the Arno River, it boasts a wealth of attractions, from the iconic Uffizi Gallery to the stunning Ponte Vecchio. Travellers flock here year-round, particularly from March to April and September, to immerse themselves in its rich art scene, bustling shopping areas, and historic piazzas. Families, culture enthusiasts, and city explorers will find plenty to enjoy, whether relaxing in the city's charming squares or indulging in local cuisine at traditional trattorias.
  • Duomo: A short stroll from Santo Spirito, the Duomo neighbourhood is renowned for its magnificent cathedral, the Florence Cathedral, with its striking dome engineered by Brunelleschi. This area, popular with visitors from July to September, offers a blend of cultural experiences, bustling markets, and shopping opportunities. Wander through its picturesque streets and discover a treasure trove of artisan shops and cafés. The vibrant atmosphere and proximity to historic landmarks make Duomo a must-visit for anyone looking to experience Florence's charm.
  • San Giovanni: Also located close to Santo Spirito, San Giovanni is a lively neighbourhood that captures the essence of Florentine life. With its historic squares and vibrant public markets, this area attracts visitors seeking a true taste of local culture, especially during the peak months of July to September. The neighbourhood is dotted with shops and eateries, making it a perfect spot for both leisurely strolls and family outings. Its rich history and central location provide easy access to many of Florence’s iconic landmarks, ensuring an enriching travel experience.

Things to do near Santo Spirito

Shopping

Only a short stroll from the main square, you can explore artisan shops in Santo Spirito, where handmade leather goods and unique ceramics abound. The vibrant Mercato di Santo Spirito offers fresh produce and local delicacies, making it an ideal spot for distinctive gifts and souvenirs.

Recreation

Experience serenity at the Spa of the Four Seasons, where you can indulge in rejuvenating treatments and unwind in their tranquil pool area. For outdoor enthusiasts, the nearby Boboli Gardens offers picturesque walking paths and lush greenery, ideal for leisurely strolls and relaxation amidst nature.

Adventure

At Mugello Circuit, located 27km from Santo Spirito, experience the thrill of motor racing in a vibrant atmosphere. Whether you're a spectator or participant, the adrenaline-fuelled events and competitive spirit create an exhilarating adventure amidst the stunning Tuscan landscape.

Nightlife

Experience the vibrant nightlife of Santo Spirito with a visit to Caffè degli Artigiani for artisanal cocktails. For a lively atmosphere, head to La Ménagerie for eclectic music and dancing. Enjoy a nightcap at Caffè L'Angolo, known for its charming vibe and friendly locals.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santo Spirito

Santo Spirito in Florence is an ideal destination for cultural and city-themed vacations, offering a rich array of attractions such as the picturesque Santo Spirito Square and the historic San Spirito Church. Visitors can immerse themselves in the local culture while enjoying family-friendly experiences in this charming neighbourhood. With its captivating piazzas and stunning palaces, Santo Spirito promises a delightful exploration of Tuscany's heritage.

  • Basilica of Santa Maria Novella: This stunning church, located 1km from Santo Spirito, showcases remarkable Gothic and Renaissance architecture. Its beautifully adorned interiors and historic frescoes offer a serene atmosphere, inviting visitors to explore its rich cultural heritage.
  • Palazzo Gondi: Situated 2km away, Palazzo Gondi is an exquisite monument that exemplifies Renaissance elegance. The intricate façade and grand interiors reflect the artistic prowess of the era, making it a captivating site for architecture enthusiasts.
  • Piazza di Santa Maria Novella: This vibrant square, located 1km from Santo Spirito, is a bustling hub of city life. Surrounded by stunning architecture and featuring lively cafés, it’s a perfect spot to soak in the local culture and atmosphere.

Best time to go to Santo Spirito

The best time to visit Santo Spirito can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santo Spirito falls in July and August. August has moderately high visitor numbers and sunny weather. The coolest average temperature around Santo Spirito falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Visiting Santo Spirito, Florence, is convenient with nearby airports. Florence (FLR-Peretola) is situated 5km away, with excellent hotel options like the 5-star Palazzo Montebello and Hotel Lungarno, both offering shuttle services. Bologna (BLQ-Guglielmo Marconi) is 85km away, featuring hotels such as the Grand Hotel Majestic già Baglioni and Starhotels Excelsior, which provide transfer services. Pisa (PSA-Galileo Galilei) is another option, located 68km from Santo Spirito, with the 5-star Hotel Pisa Tower Plaza just 3km from the airport. Each airport offers a range of transportation services to ensure a smooth journey to your accommodation.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on our traveller data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighbourhood include La Torre Del Cestello and UNA Hotels Vittoria Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 524 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Piazza di Santa Maria Novella and Piazza del Duomo are some popular places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.