A grand church interior with high vaulted ceilings, large columns, and a central altar.

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Our top choices for Santo Spirito hotels

Giano Della Bella

Giano Della Bella
Santo Spirito
Giano Della Bella

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
8.0 out of 10, Very good, (5 reviews)
"Very nice apartment and great location. The included parking and laundry facilities were the reason we selected the property, and were very happy with everything. Overall a lovely stay. "
United States
Michele
The price is ฿3,674
฿9,065 total
includes taxes & fees
7 Aug - 8 Aug
Mamo Florence - Bice & Krizia Apartments

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (228 reviews)
"Great stay"
United States
Eric
The price is ฿3,642
฿4,463 total
includes taxes & fees
11 Jul - 12 Jul
Foresteria Valdese di Firenze - Casa per Ferie

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (274 reviews)
"Great location! Staff was amazing!"
United States
Michelle
The price is ฿4,312
฿5,276 total
includes taxes & fees
26 Jul - 27 Jul
La Torre Del Cestello

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (183 reviews)
"Really nice, handy location"
United Kingdom
Kate
The price is ฿3,921
฿4,770 total
includes taxes & fees
20 Jul - 21 Jul
La Fonderia Firenze

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
8.6 out of 10, Excellent, (26 reviews)
"Very goord place to stay"
United States
Victor
The price is ฿4,047
฿4,909 total
includes taxes & fees
10 Jul - 11 Jul
L'Antica Porta Boutique B&B

Casa Vittoria by Mmega

Casa Vittoria by Mmega
Santo Spirito
2.0 out of 10, (1 review)
"El trato de la persona a cargo fue terrible nos cobró extra del precio de la renta 90 euros de limpieza solo en efectivo con una actitud muy arrogante más $35 por llegar una hora tarde después de su checkin, nunca tuvimos internet lo cual le avisamos a la brevedad y su respuesta fue que el no tenía el internet en su cartera! Terrible el trato! Nunca regresó a arreglar el internet! En la casa no hay señal y tampoco internet! "
Mexico
Estefania
The price is ฿3,026
฿7,213 total
includes taxes & fees
9 Jul - 10 Jul
Casa Vittoria by Mmega

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (174 reviews)
"Really beautiful property and wonderful room. Hotel is immaculately clean and we thought the hotel had been renovated to a beautiful finish. We let the hotel know we were staying for our 10 year anniversary, and a bottle of Prosecco was left in our room with a note, which was extremely kind. A great location to stay in, just across the river. Passcode is provided for front door so can come and go as please. Have booked to stay in again in October!"
United Kingdom
Samantha
The price is ฿7,420
฿8,695 total
includes taxes & fees
20 Jul - 21 Jul
Ottantotto Firenze

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (196 reviews)
"Pros: - great location. In quiet neighbourhood yet walkable to everywhere. Close to lovely restaurants and bakery. - "
United Kingdom
Jennifer
The price is ฿3,186
฿3,962 total
includes taxes & fees
2 Aug - 3 Aug
1900 Artevita

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (151 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is ฿3,257
฿4,039 total
includes taxes & fees
12 Jul - 13 Jul
Drom Florence Rooms & Apartments

Vettori Hideaway by MMega

Vettori Hideaway by MMega
Santo Spirito
The price is ฿3,063
฿7,250 total
includes taxes & fees
7 Aug - 8 Aug
Vettori Hideaway by MMega

Mamo Florence - Margot Apartment

Mamo Florence - Margot Apartment
Santo Spirito
10.0 out of 10, Exceptional, (4 reviews)
"Great Location walkable everywhere, quiet, spacious, perfect for our needs. The only down side is the smell from the bathrooms, but I guess Florence has that smell sometimes, like other old cities. But great over all. "
Canada
Maria
Mamo Florence - Margot Apartment

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.4 out of 10, Very good, (40 reviews)
"Great stay! The place was clean, comfortable, and exactly as described. Would definitely stay again"
United States
Diana
The price is ฿2,821
฿6,604 total
includes taxes & fees
12 Jul - 13 Jul
Appartamenti degli Artisti by Mmega

Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (102 reviews)
"Good location"
France
Leana
The price is ฿2,144
฿2,815 total
includes taxes & fees
30 Jul - 31 Jul
Palazzo Oliveto

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (231 reviews)
"What a special place! Beautiful place, large room and beautifully garden and comfortable and welcoming gathering/common area space where we were treated like old friends. Cannot wait to return."
United States
Mary Clare
The price is ฿8,344
฿9,712 total
includes taxes & fees
27 Jul - 28 Jul
AdAstra Suites

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (160 reviews)
"Excellent place"
United States
Laura Patricia
The price is ฿4,123
฿5,068 total
includes taxes & fees
28 Jul - 29 Jul
Residenza D'Epoca Al Numero 8

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"Easy check in and very helpful and polite "
United States
Remi
The price is ฿6,974
฿8,128 total
includes taxes & fees
26 Jul - 27 Jul
SPIRIT OF FLORENCE Boutique Rooms

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (129 reviews)
"We absolutely loved our 3-night stay at Oltrarno Splendid - a true hidden Gem in the best location - with cool shopping vibes and on the quieter side of the river! We loved the neighborhood feel and soaring ceilings for an authentice Florence stay with all the modern ammenities. Beautiful breakfast included and exceptionally friendly, helpful staff - shout-outs to Davide & Barbara!"
Canada
Leanne
The price is ฿8,997
฿10,430 total
includes taxes & fees
12 Jul - 13 Jul
Oltrarno Splendid

Casa Romana by Mmega

Casa Romana by Mmega
Santo Spirito
6.0 out of 10, (5 reviews)
"피렌체 열차역에서 숙소까지 걸어서 30분정도 걸렸으며, 우리가 숙소에 도착하고 나서 청소하시는 분이 청소를 하기시작하여 시간을 몇시간 낭비한거를 제외하곤 전반적으로 만족스러웠음. 6명이 지내기에 적당한 크기와 청결도도 높음. 다음에 피렌체에 다시 가게 된다면 다시 묵고 싶은 곳임. "
South Korea
Dongsam
Casa Romana by Mmega

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.4 out of 10, Exceptional, (55 reviews)
"lovely hotel - very nice staff and beautiful rooms. could be a little loud at night but not a problem. excellent location, super convenient"
United Kingdom
Hannah
The price is ฿5,104
฿6,071 total
includes taxes & fees
5 Aug - 6 Aug
Palazzo D'Oltrarno - Residenza D'Epoca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza del Duomo while you're exploring the neighbourhood.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Signoria and Uffizi Gallery are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Vibrant Piazza Santo Spirito: Experience the lively atmosphere of this bustling square, surrounded by trendy cafes and artisan shops.
  • Historic San Spirito Church: Explore this beautiful church, which showcases remarkable Renaissance architecture and art.
  • Local Market Experience: Immerse yourself in local life at the lively public market, perfect for tasting authentic Tuscan delicacies.
  • Tuscan Wine Tours: Indulge in exquisite wine tours to savour the renowned flavours of Tuscany.
  • Charming Accommodations: Choose from a delightful array of bed and breakfasts and elegant hotels for a memorable stay.

Find great hotels near Santo Spirito

In the heart of Santo Spirito, Florence, you'll discover a delightful selection of accommodations, ranging from charming bed and breakfasts to elegant hotels. This vibrant area offers a unique blend of city-themed experiences, antique furnishings, and pet-friendly options. Whether you're drawn to the historic allure of Palazzo Ridolfi or the artistic charm near Santa Croce, you'll find the perfect base for your Tuscan adventure.

  • The Social Hub Florence Lavagnini: This vibrant 4-star hotel offers a modern and stylish retreat, ideal for those seeking both adventure and business amenities. Located 2km from Santo Spirito, The Social Hub Florence Lavagnini is designed for the contemporary traveller. The property features a range of adventure sports and recreational activities both onsite and in the surrounding area, making it an excellent choice for exploring Florence. Guests can enjoy a lively atmosphere complemented by comfortable accommodations, ensuring a memorable stay.
  • B&B Hotel Firenze Pitti Palace al Ponte Vecchio: Situated 1km from Santo Spirito, this charming 4-star hotel is perfect for families and adventure seekers alike. The B&B Hotel Firenze Pitti Palace al Ponte Vecchio offers various activities, including nearby bicycle rentals for those eager to explore the scenic surroundings. Families will appreciate the dedicated amenities for children, including babysitting and childcare services available onsite, making it a convenient choice for parents travelling with little ones.
  • Grand Hotel Cavour: Located 2km from Santo Spirito, the Grand Hotel Cavour is a refined choice for families and pet owners. This 4-star establishment boasts a welcoming atmosphere with services tailored for children, such as in-room and onsite babysitting options. Additionally, the hotel accommodates pets, allowing furry companions to join in on the adventure. Guests can expect an elegant stay with amenities that cater to both relaxation and family needs, creating a home-away-from-home experience in the heart of Florence.

Where to stay near Santo Spirito

Discover the vibrant charm of Santo Spirito in Florence, where the heart of the Florentine Renaissance comes alive. Stroll through the lively Piazza Santo Spirito, surrounded by trendy cafes and artisan shops, perfect for soaking up the local atmosphere. This neighbourhood offers a unique blend of history and modernity, creating a welcoming space for relaxation and exploration. Venture nearby to experience the romantic streets and secluded corners that make Tuscany truly enchanting.

  • Florence: As the heart of Tuscany, Florence is a vibrant city brimming with culture and history. Nestled along the banks of the Arno River, it boasts a wealth of attractions, from the iconic Uffizi Gallery to the stunning Ponte Vecchio. Travellers flock here year-round, particularly from March to April and September, to immerse themselves in its rich art scene, bustling shopping areas, and historic piazzas. Families, culture enthusiasts, and city explorers will find plenty to enjoy, whether relaxing in the city's charming squares or indulging in local cuisine at traditional trattorias.
  • Duomo: A short stroll from Santo Spirito, the Duomo neighbourhood is renowned for its magnificent cathedral, the Florence Cathedral, with its striking dome engineered by Brunelleschi. This area, popular with visitors from July to September, offers a blend of cultural experiences, bustling markets, and shopping opportunities. Wander through its picturesque streets and discover a treasure trove of artisan shops and cafés. The vibrant atmosphere and proximity to historic landmarks make Duomo a must-visit for anyone looking to experience Florence's charm.
  • San Giovanni: Also located close to Santo Spirito, San Giovanni is a lively neighbourhood that captures the essence of Florentine life. With its historic squares and vibrant public markets, this area attracts visitors seeking a true taste of local culture, especially during the peak months of July to September. The neighbourhood is dotted with shops and eateries, making it a perfect spot for both leisurely strolls and family outings. Its rich history and central location provide easy access to many of Florence’s iconic landmarks, ensuring an enriching travel experience.

Things to do near Santo Spirito

Shopping

Only a short stroll from the main square, you can explore artisan shops in Santo Spirito, where handmade leather goods and unique ceramics abound. The vibrant Mercato di Santo Spirito offers fresh produce and local delicacies, making it an ideal spot for distinctive gifts and souvenirs.

Recreation

Experience serenity at the Spa of the Four Seasons, where you can indulge in rejuvenating treatments and unwind in their tranquil pool area. For outdoor enthusiasts, the nearby Boboli Gardens offers picturesque walking paths and lush greenery, ideal for leisurely strolls and relaxation amidst nature.

Adventure

At Mugello Circuit, located 27km from Santo Spirito, experience the thrill of motor racing in a vibrant atmosphere. Whether you're a spectator or participant, the adrenaline-fuelled events and competitive spirit create an exhilarating adventure amidst the stunning Tuscan landscape.

Nightlife

Experience the vibrant nightlife of Santo Spirito with a visit to Caffè degli Artigiani for artisanal cocktails. For a lively atmosphere, head to La Ménagerie for eclectic music and dancing. Enjoy a nightcap at Caffè L'Angolo, known for its charming vibe and friendly locals.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santo Spirito

Santo Spirito in Florence is an ideal destination for cultural and city-themed vacations, offering a rich array of attractions such as the picturesque Santo Spirito Square and the historic San Spirito Church. Visitors can immerse themselves in the local culture while enjoying family-friendly experiences in this charming neighbourhood. With its captivating piazzas and stunning palaces, Santo Spirito promises a delightful exploration of Tuscany's heritage.

  • Basilica of Santa Maria Novella: This stunning church, located 1km from Santo Spirito, showcases remarkable Gothic and Renaissance architecture. Its beautifully adorned interiors and historic frescoes offer a serene atmosphere, inviting visitors to explore its rich cultural heritage.
  • Palazzo Gondi: Situated 2km away, Palazzo Gondi is an exquisite monument that exemplifies Renaissance elegance. The intricate façade and grand interiors reflect the artistic prowess of the era, making it a captivating site for architecture enthusiasts.
  • Piazza di Santa Maria Novella: This vibrant square, located 1km from Santo Spirito, is a bustling hub of city life. Surrounded by stunning architecture and featuring lively cafés, it’s a perfect spot to soak in the local culture and atmosphere.

Best time to go to Santo Spirito

The best time to visit Santo Spirito can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santo Spirito falls in July and August. August has moderately high visitor numbers and sunny weather. The coolest average temperature around Santo Spirito falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Visiting Santo Spirito, Florence, is convenient with nearby airports. Florence (FLR-Peretola) is situated 5km away, with excellent hotel options like the 5-star Palazzo Montebello and Hotel Lungarno, both offering shuttle services. Bologna (BLQ-Guglielmo Marconi) is 85km away, featuring hotels such as the Grand Hotel Majestic già Baglioni and Starhotels Excelsior, which provide transfer services. Pisa (PSA-Galileo Galilei) is another option, located 68km from Santo Spirito, with the 5-star Hotel Pisa Tower Plaza just 3km from the airport. Each airport offers a range of transportation services to ensure a smooth journey to your accommodation.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on our traveller data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighbourhood include La Torre Del Cestello and UNA Hotels Vittoria Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 512 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Favourite places to visit in the surrounding area include Piazza di Santa Maria Novella, Uffizi Gallery and Piazza della Signoria. When you're sightseeing in Florence, Cathedral of Santa Maria del Fiore and Piazza del Duomo are also worth a stop.