Illinois Medical District Travel Guide

Chicago

A cityscape with a prominent skyscraper, a busy highway, and various buildings.

Things to do


Top hotels in Illinois Medical District

Congress Plaza Hotel

Congress Plaza Hotel

3.5 out of 5
520 South Michigan Avenue Chicago IL
The price is ฿3,934 per night from 22 Nov to 23 Nov
฿3,934
฿4,677 total
22 Nov - 23 Nov
includes taxes & fees
Stay at this business-friendly hotel in Chicago. Enjoy 2 restaurants, 2 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8/10 Very good! (10,095 reviews)
"We had a wonderful stay in Chicago! The hotel was great overall, and the staff really made the experience even better. John, the bartender, was fantastic, and Tina, who served us breakfast, was just the sweetest. Both deserve a special shoutout for making us feel so welcome. One thing I would love ..."

Reviewed on 15 Nov 2026

Congress Plaza Hotel
The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast

4 out of 5
1301 N State Pkwy Chicago IL
The price is ฿3,929 per night from 1 Dec to 2 Dec
฿3,929
฿4,672 total
1 Dec - 2 Dec
includes taxes & fees
Stay at this business-friendly hotel in Chicago. Enjoy free Wi-Fi, a 24-hour fitness centre and valet parking (surcharge). Our guests praise the helpful staff ...
8/10 Very good! (2,714 reviews)
"Paper thin walls, super outdated everything, lumpy mattress, noisy AC, there was dirt or something in our bath tub when we arrived, and the lobby BLARED music all evening, even when we left for the airport at 4am"

Reviewed on 15 Nov 2026

The Chicago Hotel Collection Ambassador Gold Coast
River Hotel

River Hotel

4 out of 5
75 East Wacker Drive Chicago IL
The price is ฿3,354 per night from 15 Dec to 16 Dec
฿3,354
฿3,988 total
15 Dec - 16 Dec
includes taxes & fees
Stay at this business-friendly hotel in Chicago. Enjoy free Wi-Fi, room service and a fitness centre. Our guests praise the helpful staff and the clean rooms ...
River Hotel
The Wade

The Wade

4.5 out of 5
644 N Lake Shore Dr Chicago IL
The price is ฿4,032 per night from 22 Nov to 23 Nov
฿4,032
฿4,794 total
22 Nov - 23 Nov
includes taxes & fees
Stay at this luxury hotel in Chicago. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in their ...
The Wade
The Chicago Hotel Collection - Magnificent Mile

The Chicago Hotel Collection - Magnificent Mile

4 out of 5
166 E Superior Street Chicago IL
The price is ฿3,536 per night from 23 Nov to 24 Nov
฿3,536
฿4,205 total
23 Nov - 24 Nov
includes taxes & fees
Stay at this boutique hotel in Chicago. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their ...
The Chicago Hotel Collection - Magnificent Mile
Hilton Chicago

Hilton Chicago

4 out of 5
720 S Michigan Ave Chicago IL
The price is ฿4,579 per night from 22 Nov to 23 Nov
฿4,579
฿6,439 total
22 Nov - 23 Nov
includes taxes & fees
Stay at this historic hotel in Chicago. Enjoy 2 restaurants, breakfast (surcharge) and a health club. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (3,552 reviews)
"We paid for a lake view front room, but we got put in a different room once we got to the hotel. The room was over 75 degrees when we entered, and never cooled down. Other than that, the staff was great. But for the price, there’s a lot of better options."

Reviewed on 15 Nov 2026

Hilton Chicago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

Downtown Chicago

Known for its fascinating museums, stunning river views and gorgeous architecture, there's plenty to explore in Downtown Chicago. Top attractions like Navy Pier and Michigan Avenue are major draws. Catch the metro at State Station or Clark-Lake Station to see more of the city.

Magnificent Mile

Are you interested in fascinating museums, panoramic lake views and popular shops? A visit to Magnificent Mile might be the perfect thing. You can also explore top sights like Michigan Avenue and Chicago Water Tower.

The Loop

Michigan Avenue and Lake Michigan are a few top attractions in The Loop. Hop around the city on the metro at Washington Station or Lake Station and check out the area's fascinating museums, popular shops and acclaimed art galleries.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Lincoln Park

Known for its ample dining options and fantastic lake views, there's plenty to explore in Lincoln Park. You can visit top attractions like Lake Michigan and Lincoln Hall, and jump on the metro at Fullerton Station or Armitage Station to see more of the city.



Illinois Medical District Travel Guide