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Our top choices for Illinois Medical District hotels

1. Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,549 reviews)
"Great hotel!"
United States
Bianca
The price is ฿5,903
฿7,018 total
includes taxes & fees
30 Jun - 1 Jul
Hyatt House Chicago Medical/University District

2. Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (629 reviews)
"Fantastic location. Extremely happy with accommodations."
United States
Guadalupe
The price is ฿5,233
฿6,221 total
includes taxes & fees
5 Jul - 6 Jul
Hampton Inn & Suites Chicago Medical District UIC

3. Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,495 reviews)
"Loved this hotel and location. Very well appointed for the price and the staff was great."
United States
Timothy
The price is ฿6,051
฿7,195 total
includes taxes & fees
30 Jun - 1 Jul
Hyatt Place Chicago Medical/University District

4. Hyatt Regency Chicago

Hyatt Regency Chicago
4.0 star property
The Loop, 4.8 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,457 reviews)
"Staff was great."
United States
Marianne
The price is ฿7,093
฿9,609 total
includes taxes & fees
9 Jul - 10 Jul
Hyatt Regency Chicago

5. Swissotel - Chicago

Swissotel - Chicago
4.5 star property
5 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,414 reviews)
"The property was clean and the location was perfect!"
United States
Martha
The price is ฿4,720
฿6,772 total
includes taxes & fees
1 Jul - 2 Jul
Swissotel - Chicago

6. Omni Chicago Hotel

Omni Chicago Hotel
4.5 star property
Streeterville, 5 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,823 reviews)
"All around great property and a wonderful location"
United States
Bruce
The price is ฿4,324
฿6,238 total
includes taxes & fees
8 Jul - 9 Jul
Omni Chicago Hotel

7. LondonHouse Chicago, Curio Collection by Hilton

LondonHouse Chicago, Curio Collection by Hilton
4.5 star property
The Loop, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,757 reviews)
"Great location!"
United States
William
The price is ฿7,811
฿10,254 total
includes taxes & fees
5 Jul - 6 Jul
LondonHouse Chicago, Curio Collection by Hilton

8. Aloft by Marriott Chicago Mag Mile

Aloft by Marriott Chicago Mag Mile
3.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.6 out of 10, Excellent, (3,301 reviews)
"Very great hotel"
United States
Allesandra
The price is ฿5,340
฿6,348 total
includes taxes & fees
1 Jul - 2 Jul
Aloft by Marriott Chicago Mag Mile

9. Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (4,514 reviews)
"Clean room, great breakfast and close to everything we needed"
United States
Kyle
The price is ฿5,900
฿7,954 total
includes taxes & fees
6 Jul - 7 Jul
Hotel Riu Plaza Chicago

10. Hilton Chicago/Magnificent Mile Suites

Hilton Chicago/Magnificent Mile Suites
3.5 star property
Streeterville, 5.6 km from Illinois Medical District
9.0 out of 10, Wonderful, (4,465 reviews)
"Great stay!"
United States
Avradita
The price is ฿4,597
฿5,466 total
includes taxes & fees
7 Jul - 8 Jul
Hilton Chicago/Magnificent Mile Suites

11. River Hotel

River Hotel
4.0 star property
The Loop, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (5,259 reviews)
"Excellent place to stay, as we found it central & walkable to most parks & attractions. The place was spotless & the staff were fantastic."
Canada
Jody
The price is ฿4,579
฿5,443 total
includes taxes & fees
6 Jul - 7 Jul
River Hotel

12. SureStay Plus Hotel by Best Western Chicago Lombard

SureStay Plus Hotel by Best Western Chicago Lombard
2.5 star property
27.8 km from Illinois Medical District
9.0 out of 10, Wonderful, (2,826 reviews)
"Great stay"
United States
Keisha
The price is ฿3,032
฿3,365 total
includes taxes & fees
28 Jun - 29 Jun
SureStay Plus Hotel by Best Western Chicago Lombard

13. Hyatt Place Itasca

Hyatt Place Itasca
3.0 star property
30.3 km from Illinois Medical District
8.8 out of 10, Excellent, (1,159 reviews)
"Great hotel friendly staff!"
United States
Kathryn
The price is ฿3,894
฿4,322 total
includes taxes & fees
25 Jun - 26 Jun
Hyatt Place Itasca

14. Hyatt Regency O'Hare Chicago

Hyatt Regency O'Hare Chicago
4.0 star property
19.7 km from Illinois Medical District
8.8 out of 10, Excellent, (2,721 reviews)
"Hotel was clean, very friendly staff and conveniently located from the airport"
United States
Jason
The price is ฿4,193
฿4,779 total
includes taxes & fees
29 Jun - 30 Jun
Hyatt Regency O'Hare Chicago

15. InterContinental Chicago Magnificent Mile by IHG

InterContinental Chicago Magnificent Mile by IHG
4.5 star property
Magnificent Mile, 4.9 km from Illinois Medical District
9.2 out of 10, Wonderful, (3,126 reviews)
"Clean and spacious room, staff was great. Great location easy to walk to other activities and restaurants."
United States
Sabrina
The price is ฿7,119
฿9,618 total
includes taxes & fees
6 Jul - 7 Jul
InterContinental Chicago Magnificent Mile by IHG

16. Sheraton Grand Chicago Riverwalk

Sheraton Grand Chicago Riverwalk
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
8.6 out of 10, Excellent, (1,689 reviews)
"Location was great"
United States
Pamela
The price is ฿7,218
฿9,757 total
includes taxes & fees
5 Jul - 6 Jul
Sheraton Grand Chicago Riverwalk

17. Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very good, (10,167 reviews)
"Great stay!"
United States
Daniel
The price is ฿4,496
฿5,345 total
includes taxes & fees
29 Jun - 30 Jun
Congress Plaza Hotel

18. Travelodge by Wyndham Downtown Chicago

Travelodge by Wyndham Downtown Chicago
2.0 star property
The Loop, 4.2 km from Illinois Medical District
7.6 out of 10, Good, (2,642 reviews)
"Great location and helpful staff."
United States
Ming
The price is ฿4,062
฿4,830 total
includes taxes & fees
5 Jul - 6 Jul
Travelodge by Wyndham Downtown Chicago

19. Fairmont Chicago at Millennium Park

Fairmont Chicago at Millennium Park
4.5 star property
The Loop, 4.8 km from Illinois Medical District
8.8 out of 10, Excellent, (2,222 reviews)
"Location is excellent!"
United States
Michele
The price is ฿7,773
฿10,418 total
includes taxes & fees
8 Jul - 9 Jul
Fairmont Chicago at Millennium Park

20. Hilton Chicago

Hilton Chicago
4.0 star property
The Loop, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,889 reviews)
"Great stay"
United States
Jose saul
The price is ฿7,542
฿9,934 total
includes taxes & fees
19 Jul - 20 Jul
Hilton Chicago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

Shopaholics need look no further this glittering street packed with boutique and luxury shops, famous department stores and cafes.

The Loop

Bordered roughly by the surrounding elevated train circuit, this Chicago neighborhood has restaurants, galleries, parks and a giant silver bean.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Lincoln Park

Both a neighborhood and a park, this northern Chicago area has gorgeous scenery, residential streets lined with stately homes and extensive shopping and dining.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 16 hotels and other accommodation options in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.
What can I see and do in this Chicago neighbourhood?
Don't miss favourite places to visit in the surrounding area, such as Soldier Field, Michigan Avenue and United Center. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.