Search Hotels in Illinois Medical District, Chicago

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Our top choices for Illinois Medical District hotels

Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (587 reviews)
"Everything was great, from the staff to the room, amenities and breakfast."
United States
Lisa
The price is ฿4,903
฿5,829 total
includes taxes & fees
25 May - 26 May
Hampton Inn & Suites Chicago Medical District UIC

Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,530 reviews)
"Very good stay and locatipn."
United States
Patricia
The price is ฿5,768
฿6,857 total
includes taxes & fees
25 May - 26 May
Hyatt House Chicago Medical/University District

Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,501 reviews)
"Excellent place to stay! Breakfast was great and super friendly staff!"
United States
Michelle
The price is ฿5,478
฿6,512 total
includes taxes & fees
25 May - 26 May
Hyatt Place Chicago Medical/University District

Silversmith Hotel Chicago Downtown

Silversmith Hotel Chicago Downtown
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
9.2 out of 10, Wonderful, (2,258 reviews)
"Close to many attractions and shopping and nice unique hotel"
United States
Brittany
The price is ฿3,842
฿5,552 total
includes taxes & fees
25 May - 26 May
Silversmith Hotel Chicago Downtown

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton
4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,493 reviews)
"Great place to stay "
United States
Mark
The price is ฿5,934
฿8,170 total
includes taxes & fees
26 May - 27 May
Sable at Navy Pier Chicago, Curio Collection by Hilton

Palmer House a Hilton Hotel

Palmer House a Hilton Hotel
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,431 reviews)
"We had a wonderful stay. Enjoyed breakfast at the hotel, with wonderful, attentive staff. "
United States
Cynthia
The price is ฿4,780
฿6,645 total
includes taxes & fees
25 May - 26 May
Palmer House a Hilton Hotel

Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (4,086 reviews)
"Great hotel in an amazing location!"
United States
Samer
The price is ฿4,816
฿6,646 total
includes taxes & fees
27 May - 28 May
Hotel Riu Plaza Chicago

The Wade

The Wade
4.5 star property
Streeterville, 5.6 km from Illinois Medical District
8.4 out of 10, Very good, (1,831 reviews)
"We enjoy our stay."
United States
Nuria
The price is ฿4,170
฿4,957 total
includes taxes & fees
10 May - 11 May
The Wade

Freehand Chicago

Freehand Chicago
4.0 star property
River North, 4.7 km from Illinois Medical District
8.0 out of 10, Very good, (2,961 reviews)
"Great central location, lots to do nearby."
United States
Michael
The price is ฿3,016
฿4,161 total
includes taxes & fees
25 May - 26 May
Freehand Chicago

Swissotel - Chicago

Swissotel - Chicago
4.5 star property
5 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,310 reviews)
"Breakfasr good, view great"
United States
Jan
The price is ฿6,631
฿9,018 total
includes taxes & fees
25 May - 26 May
Swissotel - Chicago

Hilton Garden Inn Chicago Downtown South Loop

Hilton Garden Inn Chicago Downtown South Loop
3.0 star property
The Loop, 4.1 km from Illinois Medical District
8.8 out of 10, Excellent, (1,985 reviews)
"Had a great stay-5 stars of 5"
United States
donald
The price is ฿4,231
฿5,030 total
includes taxes & fees
26 May - 27 May
Hilton Garden Inn Chicago Downtown South Loop

Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very good, (10,185 reviews)
"Great stay"
United States
Matthew
The price is ฿4,304
฿5,117 total
includes taxes & fees
10 May - 11 May
Congress Plaza Hotel

Arlo Chicago

Arlo Chicago
4.0 star property
Theatre District, 4.5 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,114 reviews)
"Great breakfast and staff. "
United States
Kelly
The price is ฿4,334
฿6,130 total
includes taxes & fees
25 May - 26 May
Arlo Chicago

FOUND Hotel Chicago River North

FOUND Hotel Chicago River North
2.0 star property
River North, 4.3 km from Illinois Medical District
8.4 out of 10, Very good, (595 reviews)
"Great stay!"
United States
Vanessa
The price is ฿3,846
฿4,515 total
includes taxes & fees
10 May - 11 May
FOUND Hotel Chicago River North

Eurostars Magnificent Mile

Eurostars Magnificent Mile
4.0 star property
River North, 4.8 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,514 reviews)
"The hotel was phenomenally clean, the staff was nice !"
United States
Rochelle
The price is ฿4,654
฿5,534 total
includes taxes & fees
11 May - 12 May
Eurostars Magnificent Mile

Hilton Chicago

Hilton Chicago
4.0 star property
The Loop, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,780 reviews)
"Clean room and great location "
United States
Diana
The price is ฿5,139
฿7,059 total
includes taxes & fees
25 May - 26 May
Hilton Chicago

Fairmont Chicago at Millennium Park

Fairmont Chicago at Millennium Park
4.5 star property
The Loop, 4.8 km from Illinois Medical District
8.8 out of 10, Excellent, (2,150 reviews)
"A great option to stay in the city! Nice hotel and friendly staff."
United States
Nicole
The price is ฿6,217
฿8,545 total
includes taxes & fees
26 May - 27 May
Fairmont Chicago at Millennium Park

Sheraton Grand Chicago Riverwalk

Sheraton Grand Chicago Riverwalk
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
8.6 out of 10, Excellent, (1,627 reviews)
"It was very clean, beautiful place"
United States
Grisel
The price is ฿6,931
฿9,390 total
includes taxes & fees
25 May - 26 May
Sheraton Grand Chicago Riverwalk

The Chicago Hotel Collection - Magnificent Mile

The Chicago Hotel Collection - Magnificent Mile
4.0 star property
Streeterville, 5.2 km from Illinois Medical District
7.8 out of 10, Good, (1,382 reviews)
"The bar was well stocked and the bar staff was great!!"
United States
Daynese
The price is ฿3,912
฿4,652 total
includes taxes & fees
11 May - 12 May
The Chicago Hotel Collection - Magnificent Mile

Staypineapple, An Iconic Hotel, The Loop

Staypineapple, An Iconic Hotel, The Loop
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
9.4 out of 10, Exceptional, (1,061 reviews)
"Wonderful restaurant, amazing food."
United States
Robert
The price is ฿4,286
฿6,051 total
includes taxes & fees
25 May - 26 May
Staypineapple, An Iconic Hotel, The Loop
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

Shopaholics need look no further this glittering street packed with boutique and luxury shops, famous department stores and cafes.

The Loop

Bordered roughly by the surrounding elevated train circuit, this Chicago neighborhood has restaurants, galleries, parks and a giant silver bean.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Lincoln Park

Both a neighborhood and a park, this northern Chicago area has gorgeous scenery, residential streets lined with stately homes and extensive shopping and dining.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 17 hotels and other accommodation options in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.
What can I see and do in this Chicago neighbourhood?
Don't miss favourite places to visit in the surrounding area, such as United Center, Soldier Field and Michigan Avenue. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.