Search Hotels in Illinois Medical District, Chicago

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Illinois Medical District hotels

Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,531 reviews)
"Very good stay and locatipn."
United States
Patricia
The price is ฿5,786
฿6,879 total
includes taxes & fees
25 May - 26 May
Hyatt House Chicago Medical/University District

Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,501 reviews)
"Excellent place to stay! Breakfast was great and super friendly staff!"
United States
Michelle
The price is ฿5,495
฿6,533 total
includes taxes & fees
25 May - 26 May
Hyatt Place Chicago Medical/University District

Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (587 reviews)
"Everything was great, from the staff to the room, amenities and breakfast."
United States
Lisa
The price is ฿4,918
฿5,847 total
includes taxes & fees
25 May - 26 May
Hampton Inn & Suites Chicago Medical District UIC

LondonHouse Chicago, Curio Collection by Hilton

LondonHouse Chicago, Curio Collection by Hilton
4.5 star property
The Loop, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,708 reviews)
"Amazing hotel and staff!"
United States
erin
The price is ฿5,852
฿7,906 total
includes taxes & fees
26 May - 27 May
LondonHouse Chicago, Curio Collection by Hilton

Hyatt Regency Chicago

Hyatt Regency Chicago
4.0 star property
The Loop, 4.8 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,516 reviews)
"Clean room , nice staff, nice view"
United States
John Hok-Lam
The price is ฿7,757
฿10,376 total
includes taxes & fees
25 May - 26 May
Hyatt Regency Chicago

Swissotel - Chicago

Swissotel - Chicago
4.5 star property
5 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,310 reviews)
"Breakfasr good, view great"
United States
Jan
The price is ฿6,651
฿9,046 total
includes taxes & fees
24 May - 25 May
Swissotel - Chicago

Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (4,091 reviews)
"Great hotel in an amazing location!"
United States
Samer
The price is ฿4,797
฿6,621 total
includes taxes & fees
27 May - 28 May
Hotel Riu Plaza Chicago

The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast
4.0 star property
Gold Coast, 5.6 km from Illinois Medical District
8.2 out of 10, Very good, (1,425 reviews)
"Great stay, love the surrounding area. Rooms a bit small but overall a great stay. "
United States
Eric
The price is ฿4,328
฿5,146 total
includes taxes & fees
12 May - 13 May
The Chicago Hotel Collection Ambassador Gold Coast

Sheraton Grand Chicago Riverwalk

Sheraton Grand Chicago Riverwalk
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
8.6 out of 10, Excellent, (1,627 reviews)
"It was very clean, beautiful place"
United States
Grisel
The price is ฿7,534
฿10,110 total
includes taxes & fees
24 May - 25 May
Sheraton Grand Chicago Riverwalk

Hilton Chicago

Hilton Chicago
4.0 star property
The Loop, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,783 reviews)
"Clean room and great location "
United States
Diana
The price is ฿5,120
฿7,032 total
includes taxes & fees
26 May - 27 May
Hilton Chicago

Aloft Chicago Mag Mile

Aloft Chicago Mag Mile
3.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.6 out of 10, Excellent, (3,231 reviews)
"The design of the property and location is great!"
United States
Fedna
The price is ฿5,120
฿6,087 total
includes taxes & fees
26 May - 27 May
Aloft Chicago Mag Mile

River Hotel

River Hotel
4.0 star property
The Loop, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (5,185 reviews)
"Perfect for couples and the location is amazing"
United States
Jaden
The price is ฿4,626
฿5,499 total
includes taxes & fees
25 May - 26 May
River Hotel

Sonesta ES Suites Chicago Downtown Magnificent Mile - Medical

Sonesta ES Suites Chicago Downtown Magnificent Mile - Medical
3.0 star property
Streeterville, 5.6 km from Illinois Medical District
8.6 out of 10, Excellent, (2,459 reviews)
"Great place to stay."
United States
Yuge
The price is ฿4,740
฿5,635 total
includes taxes & fees
10 May - 11 May
Sonesta ES Suites Chicago Downtown Magnificent Mile - Medical

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton
4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,495 reviews)
"Great place to stay "
United States
Mark
The price is ฿6,874
฿9,287 total
includes taxes & fees
26 May - 27 May
Sable at Navy Pier Chicago, Curio Collection by Hilton

Warwick Allerton - Chicago

Warwick Allerton - Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
8.6 out of 10, Excellent, (3,051 reviews)
"Great location right off magnificent mile and close to everything. "
United States
Natalia
The price is ฿4,396
฿6,175 total
includes taxes & fees
12 May - 13 May
Warwick Allerton - Chicago

Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very good, (10,189 reviews)
"Great stay"
United States
Matthew
The price is ฿4,317
฿5,132 total
includes taxes & fees
10 May - 11 May
Congress Plaza Hotel

Sofitel Chicago Magnificent Mile

Sofitel Chicago Magnificent Mile
4.5 star property
5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,449 reviews)
"Great hotel, clean and modern"
United States
Wyatt
The price is ฿6,952
฿9,227 total
includes taxes & fees
25 May - 26 May
Sofitel Chicago Magnificent Mile

Omni Chicago Hotel

Omni Chicago Hotel
4.5 star property
Streeterville, 5 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,782 reviews)
"Absolutely amazing staff and location. "
United States
Maria
The price is ฿5,635
฿7,772 total
includes taxes & fees
25 May - 26 May
Omni Chicago Hotel

Embassy Suites by Hilton Chicago Downtown Magnificent Mile

Embassy Suites by Hilton Chicago Downtown Magnificent Mile
4.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.2 out of 10, Very good, (2,852 reviews)
"Great stay"
United States
Darin
The price is ฿5,620
฿7,630 total
includes taxes & fees
10 May - 11 May
Embassy Suites by Hilton Chicago Downtown Magnificent Mile

Palmer House a Hilton Hotel

Palmer House a Hilton Hotel
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,432 reviews)
"We had a wonderful stay. Enjoyed breakfast at the hotel, with wonderful, attentive staff. "
United States
Cynthia
The price is ฿5,603
฿7,618 total
includes taxes & fees
25 May - 26 May
Palmer House a Hilton Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

Shopaholics need look no further this glittering street packed with boutique and luxury shops, famous department stores and cafes.

The Loop

Bordered roughly by the surrounding elevated train circuit, this Chicago neighborhood has restaurants, galleries, parks and a giant silver bean.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Lincoln Park

Both a neighborhood and a park, this northern Chicago area has gorgeous scenery, residential streets lined with stately homes and extensive shopping and dining.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 17 hotels and other accommodation options in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.
What can I see and do in this Chicago neighbourhood?
Don't miss favourite places to visit in the surrounding area, such as United Center, Soldier Field and Michigan Avenue. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.