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Search Hotels in Illinois Medical District, Chicago

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Our top choices for Illinois Medical District hotels

1. Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.2 out of 10, Wonderful, (1,577 reviews)
"Very hospitable staff and the breakfast was an awesome plus"
United States
Sharitta
The price is ฿7,124
฿8,469 total
includes taxes & fees
16 Aug - 17 Aug
Hyatt House Chicago Medical/University District

2. Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,481 reviews)
"Great hotel"
United States
Kathy
The price is ฿6,693
฿7,957 total
includes taxes & fees
16 Aug - 17 Aug
Hyatt Place Chicago Medical/University District

3. Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (689 reviews)
"Clean room, great location and friendly staff."
United States
Hector
The price is ฿5,521
฿6,563 total
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn & Suites Chicago Medical District UIC

4. Hyatt House Chicago/West Loop-Fulton Market

Hyatt House Chicago/West Loop-Fulton Market
3.5 star property
2.3 km from Illinois Medical District
9.0 out of 10, Wonderful, (1,317 reviews)
"Very nice hotel"
United States
Hadi
The price is ฿6,718
฿7,987 total
includes taxes & fees
23 Aug - 24 Aug
Hyatt House Chicago/West Loop-Fulton Market

5. Crowne Plaza Chicago West Loop by IHG

Crowne Plaza Chicago West Loop by IHG
3.5 star property
2.7 km from Illinois Medical District
9.0 out of 10, Wonderful, (2,477 reviews)
"Excelente hotel"
Mexico
Evelyn
The price is ฿5,154
฿6,128 total
includes taxes & fees
30 Aug - 31 Aug
Crowne Plaza Chicago West Loop by IHG

6. Homewood Suites by Hilton Chicago West Loop Fulton Mkt Area

Homewood Suites by Hilton Chicago West Loop Fulton Mkt Area
3.0 star property
3.1 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,013 reviews)
"Great location"
United States
Carmen
The price is ฿4,472
฿5,317 total
includes taxes & fees
23 Aug - 24 Aug
Homewood Suites by Hilton Chicago West Loop Fulton Mkt Area

7. Hyatt Place Chicago/Downtown - The Loop

Hyatt Place Chicago/Downtown - The Loop
3.0 star property
The Loop, 3.6 km from Illinois Medical District
8.8 out of 10, Excellent, (1,505 reviews)
"Enjoyed my stay!"
United States
Kimberly
The price is ฿5,334
฿6,342 total
includes taxes & fees
7 Sept - 8 Sept
Hyatt Place Chicago/Downtown - The Loop

8. La Quinta Inn & Suites by Wyndham Chicago Downtown

La Quinta Inn & Suites by Wyndham Chicago Downtown
3.0 star property
The Loop, 3.6 km from Illinois Medical District
8.6 out of 10, Excellent, (2,868 reviews)
"This property is so nice to stay at, will continue to stay here in the future."
United States
Paige
The price is ฿5,427
฿7,043 total
includes taxes & fees
7 Sept - 8 Sept
La Quinta Inn & Suites by Wyndham Chicago Downtown

9. Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (4,942 reviews)
"Very nice and rooms were amazing. Loved the location and the breakfast buffet!"
United States
Cicely
The price is ฿6,565
฿8,748 total
includes taxes & fees
30 Aug - 31 Aug
Hotel Riu Plaza Chicago

10. The Emily Hotel

The Emily Hotel
4.0 star property
2.8 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,336 reviews)
"Excellent location and the room was very nice and quiet."
United States
Heather
The price is ฿8,203
฿9,752 total
includes taxes & fees
9 Aug - 10 Aug
The Emily Hotel

11. Hyatt Regency Chicago

Hyatt Regency Chicago
4.0 star property
The Loop, 4.8 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,496 reviews)
"Great hotel in great location"
United States
Emily
The price is ฿7,422
฿10,006 total
includes taxes & fees
30 Aug - 31 Aug
Hyatt Regency Chicago

12. L7 Chicago by LOTTE

L7 Chicago by LOTTE
4.5 star property
Theatre District, 4.5 km from Illinois Medical District
9.6 out of 10, Exceptional, (4,516 reviews)
"Great stay"
United States
Julie Ann
The price is ฿6,225
฿7,400 total
includes taxes & fees
9 Aug - 10 Aug
L7 Chicago by LOTTE

13. Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel
4.0 star property
The Loop, 3.8 km from Illinois Medical District
9.6 out of 10, Exceptional, (1,299 reviews)
"Very helpful front desk staff and friendly cleaners. Very pleasant stay"
United States
Aleace
The price is ฿5,533
฿6,578 total
includes taxes & fees
30 Aug - 31 Aug
Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

14. Omni Chicago Hotel

Omni Chicago Hotel
4.5 star property
Streeterville, 5 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,979 reviews)
"Great location"
United States
Melissa
The price is ฿7,380
฿9,876 total
includes taxes & fees
9 Aug - 10 Aug
Omni Chicago Hotel

15. InterContinental Chicago Magnificent Mile by IHG

InterContinental Chicago Magnificent Mile by IHG
4.5 star property
Magnificent Mile, 4.9 km from Illinois Medical District
9.2 out of 10, Wonderful, (3,188 reviews)
"Amazing stay"
United States
Jose
The price is ฿8,405
฿11,151 total
includes taxes & fees
2 Sept - 3 Sept
InterContinental Chicago Magnificent Mile by IHG

16. Hilton Garden Inn Chicago Central Loop

Hilton Garden Inn Chicago Central Loop
3.0 star property
The Loop, 3.5 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,402 reviews)
"Very nice would stay again"
United States
Dawn
The price is ฿5,295
฿6,295 total
includes taxes & fees
7 Sept - 8 Sept
Hilton Garden Inn Chicago Central Loop

17. Hyatt Place Chicago/River North

Hyatt Place Chicago/River North
3.5 star property
River North, 4.4 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,892 reviews)
"Great location, good breakfast and super nice staff"
United States
Michelle
The price is ฿5,626
฿6,688 total
includes taxes & fees
30 Aug - 31 Aug
Hyatt Place Chicago/River North

18. Hilton Chicago

Hilton Chicago
4.0 star property
The Loop, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,994 reviews)
"Great location, friendly staff, various amenities for the family."
Canada
kun
The price is ฿5,604
฿7,636 total
includes taxes & fees
7 Sept - 8 Sept
Hilton Chicago

19. Holiday Inn Chicago Dwtn - The Mart by IHG

Holiday Inn Chicago Dwtn - The Mart by IHG
3.0 star property
River North, 3.7 km from Illinois Medical District
8.8 out of 10, Excellent, (2,491 reviews)
"Great stay"
United States
James
The price is ฿6,731
฿8,988 total
includes taxes & fees
9 Aug - 10 Aug
Holiday Inn Chicago Dwtn - The Mart by IHG

20. Hyatt Centric The Loop Chicago

Hyatt Centric The Loop Chicago
4.0 star property
Theatre District, 3.9 km from Illinois Medical District
9.0 out of 10, Wonderful, (2,687 reviews)
"Great location"
United States
Dee
The price is ฿6,155
฿8,146 total
includes taxes & fees
23 Aug - 24 Aug
Hyatt Centric The Loop Chicago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

The Loop

Bordered roughly by the surrounding elevated train circuit, this Chicago neighborhood has restaurants, galleries, parks and a giant silver bean.

Magnificent Mile

Shopaholics need look no further this glittering street packed with boutique and luxury shops, famous department stores and cafes.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Theatre District

While you're in Theatre District, take in top sights like Michigan Avenue or State Street, and hop on the metro to see more of the city at Washington Station or Monroe Station (Blue Line).

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 16 hotels and other accommodation options in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.
What can I see and do in this Chicago neighbourhood?
Don't miss favourite places to visit in the surrounding area, such as United Center, Soldier Field and Michigan Avenue. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.