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Check prices for these dates

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27 Feb - 28 Feb
Tomorrow
28 Feb - 1 Mar
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar

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Our top choices for South San Francisco hotels

Bar (on property)

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side
8.6 out of 10, Excellent, (1,304 reviews)
"It was a nice room with a great breakfast 😋 "
United States
Joshua Joseph
The price is ฿4,283
฿5,033 total
includes taxes & fees
14 Mar - 15 Mar
Embassy Suites by Hilton San Francisco Airport Oyster Point
Lobby

DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
South San Francisco
8.4 out of 10, Very good, (2,141 reviews)
"Clean room, safe, excellent service"
United States
Nathan
The price is ฿3,206
฿3,787 total
includes taxes & fees
7 Mar - 8 Mar
DoubleTree by Hilton San Francisco South Airport Blvd
Terrace/patio

Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
3.0 star property
The East Side
8.8 out of 10, Excellent, (1,189 reviews)
"Had an amazing stay here, felt like home "
United States
Miguel
The price is ฿3,565
฿4,175 total
includes taxes & fees
14 Mar - 15 Mar
Home2 Suites by Hilton San Francisco Airport North
View from property

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
4.0 star property
Oyster Point
9.2 out of 10, Wonderful, (1,001 reviews)
"Great place to stay and staff are helpful. "
United States
Smile
The price is ฿3,608
฿4,314 total
includes taxes & fees
21 Mar - 22 Mar
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
Exterior

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (2,033 reviews)
"Pleasant stay "
United States
Alok
The price is ฿3,330
฿3,906 total
includes taxes & fees
28 Feb - 1 Mar
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Bar (on property)

Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
South San Francisco
8.4 out of 10, Very good, (1,723 reviews)
"Great food, clean room, great service!"
United States
Shruti
The price is ฿2,858
฿3,379 total
includes taxes & fees
28 Feb - 1 Mar
Best Western Plus Grosvenor Airport Hotel
Lobby sitting area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
3.0 star property
The East Side
9.0 out of 10, Wonderful, (458 reviews)
"Clean room, helpful staff, complimentary breakfast. "
United States
Veronica
The price is ฿3,886
฿4,544 total
includes taxes & fees
6 Mar - 7 Mar
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
Reception

Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
3.0 star property
The East Side
8.6 out of 10, Excellent, (1,001 reviews)
"rooms are spacious and staff is very helpful"
United States
RAVINDER
The price is ฿2,847
฿3,350 total
includes taxes & fees
7 Mar - 8 Mar
Hilton Garden Inn San Francisco Arpt North
Standard Room, 2 Queen Beds | In-room safe, desk, blackout curtains, iron/ironing board

Days Inn by Wyndham San Francisco S/Oyster Point Airport

Days Inn by Wyndham San Francisco S/Oyster Point Airport
2.0 star property
Paradise Valley
8.8 out of 10, Excellent, (6 reviews)
"The room was nice and clean. "
United States
Kyle
The price is ฿2,669
฿3,213 total
includes taxes & fees
1 Mar - 2 Mar
Days Inn by Wyndham San Francisco S/Oyster Point Airport
Lobby

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North
2.0 star property
South San Francisco
6.0 out of 10, (3,234 reviews)
"Staff were very pleasant "
United States
Karla
The price is ฿1,865
฿2,234 total
includes taxes & fees
1 Mar - 2 Mar
Travelodge by Wyndham San Francisco Airport North
Exterior

Hampton Inn San Francisco Airport

Hampton Inn San Francisco Airport
2.5 star property
The East Side
8.8 out of 10, Excellent, (1,003 reviews)
"Amazing place, 100% recommend "
United States
Ana catherine
The price is ฿3,469
฿4,106 total
includes taxes & fees
7 Mar - 8 Mar
Hampton Inn San Francisco Airport
Reception

Hotel Focus SFO

Hotel Focus SFO
3.0 star property
The East Side
7.6 out of 10, Good, (1,533 reviews)
"Good place to stay"
United States
Ricardo
The price is ฿2,745
฿3,233 total
includes taxes & fees
20 Mar - 21 Mar
Hotel Focus SFO
Exterior

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.6 out of 10, Excellent, (1,977 reviews)
"I love this hotel :)"
United States
Daniel
The price is ฿3,263
฿3,893 total
includes taxes & fees
1 Mar - 2 Mar
Sonesta Select San Francisco Airport Oyster Point Waterfront
Exterior

Holiday Inn Express San Francisco-Airport North by IHG

Holiday Inn Express San Francisco-Airport North by IHG
2.5 star property
South San Francisco
8.2 out of 10, Very good, (1,001 reviews)
"Great room delicious breakfast wonderful customer service "
United States
Stephanie
The price is ฿2,769
฿3,622 total
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express San Francisco-Airport North by IHG
Frette Italian sheets, premium bedding, pillow-top beds, desk

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.4 out of 10, Very good, (1,002 reviews)
"It was a great stay, clean, comfortable wirh everything you need!"
United States
Chee
The price is ฿3,482
฿4,132 total
includes taxes & fees
29 Mar - 30 Mar
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Terrace/patio

Comfort Inn and Suites San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North
2.5 star property
The East Side
7.8 out of 10, Good, (1,002 reviews)
"Hotel is rather old but very clean and comfortable. Staff was very friendly. Fitness area could use some work - treadmill didn’t work at all. "
United States
Gwyn M
The price is ฿3,045
฿3,578 total
includes taxes & fees
28 Feb - 1 Mar
Comfort Inn and Suites San Francisco Airport North
Lobby

Four Points by Sheraton Hotel & Suites San Francisco Airport

Four Points by Sheraton Hotel & Suites San Francisco Airport
3.0 star property
South San Francisco
7.8 out of 10, Good, (999 reviews)
"all good; the staff, the room, the breakfast; i would definitely stay there again."
United States
Bennett
The price is ฿2,953
฿3,472 total
includes taxes & fees
6 Mar - 7 Mar
Four Points by Sheraton Hotel & Suites San Francisco Airport
Property entrance

Larkspur Landing Extended Stay Suites South San Francisco

Larkspur Landing Extended Stay Suites South San Francisco
3.0 star property
The East Side
7.8 out of 10, Good, (1,001 reviews)
"Friendly staff and the room was clean. "
United States
Sia
The price is ฿4,203
฿4,941 total
includes taxes & fees
29 Mar - 30 Mar
Larkspur Landing Extended Stay Suites South San Francisco
Lobby

Rodeway Inn South San Francisco Airport

Rodeway Inn South San Francisco Airport
2.0 star property
South San Francisco
7.0 out of 10, Good, (1,001 reviews)
"Room good"
United States
Dmitri
The price is ฿2,251
฿2,661 total
includes taxes & fees
8 Mar - 9 Mar
Rodeway Inn South San Francisco Airport
Interior detail

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (990 reviews)
"Very clean room, friendly staff and secure parking."
United States
Christopher
The price is ฿3,078
฿3,609 total
includes taxes & fees
28 Feb - 1 Mar
Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South San Francisco

Find the best South San Francisco areas for the activities you enjoy most.
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Downtown South San Francisco

City centre South San Francisco blends business energy with cultural richness just minutes from San Francisco proper. Modern biotech campuses stand alongside vibrant ethnic markets on Grand Avenue. The area hums with professional activity while celebrating its diverse heritage through colourful murals. This well-connected hub offers excellent transport options via BART and Caltrain stations. Authentic dining reflects the area's Hispanic and Asian communities. After business hours, the atmosphere becomes quietly residential with limited evening entertainment.

Wooden boardwalk through the tidal marshes of Alviso, Don Edwards San Francisco Bay National Wildlife Refuge, San Jose, California; sunset view

Oyster Point

Oyster Point blends sleek biotech campuses with refreshing waterfront beauty along San Francisco Bay. Modern glass buildings reflect the calm waters where walking paths invite you to explore. The area showcases contemporary plazas and public art installations throughout the business district. Corporate lunch spots serve the weekday crowd while evening options remain limited. The Bay Trail offers panoramic views and peaceful walks away from the office buzz. Visitors can observe both cutting-edge architecture and natural bay ecosystems during business hours.

#BVSBlue Aristodes Demetries, One Of Americas Best Known Sculptors Created This Steel Sculpture As A Symbol Of Cabot Cabot And Forbes Industrial Park. Situated 243 Feet Above Sea Level It Rises To A Be Seen From The Bay Bridge, The East Bay and SFO. Called The Wind Harp Locally. It emits eerie sounds when the wind 💨is at its strongest.
Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀
Open Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

The East Side

The East Side of South San Francisco blends cultural diversity with suburban charm just minutes from San Francisco Bay. Hispanic and Asian communities contribute authentic flavours to local eateries along Grand Avenue. Views of San Bruno Mountain create a distinctive backdrop for this working-class area. Visitors can explore Orange Memorial Park's recreational areas or hike nearby mountain trails. Budget-conscious travellers appreciate the area's affordable dining options and practical accommodation. Easy connections to BART and Caltrain make exploring the greater Bay Area convenient without downtown's premium prices.

Landscape in Joseph Grant County Park on a cloudy day, San Jose, south San Francisco bay area, California

Paradise Valley

Paradise Valley offers a quiet retreat from San Francisco's hustle while keeping you connected to the Bay Area. This peaceful residential area boasts wide streets and modest homes where local families live their everyday lives. Travellers appreciate the genuine suburban atmosphere and significantly lower prices than city centre. Just minutes from San Francisco International Airport, Paradise Valley serves as a practical base for exploring the region. Small local parks provide green spaces for relaxation. Though lacking tourist attractions within its boundaries, the neighborhood's proximity to major highways makes Bay Area adventures easily accessible.

Avalon

Though Avalon may not have many top sights, you can venture to the surrounding area to see attractions like See's Candies and Artichoke Joe's Casino.

Stay near popular South San Francisco attractions

San Bruno Point Park

4.0/5 (181 reviews)
Point San Bruno Park offers panoramic views of San Francisco Bay and close-up aircraft sightings from nearby SFO. Stroll the waterfront trails and find a peaceful picnic spot away from the city's bustle.
See properties

South San Francisco Convention Center

3.9/5 (221 reviews)
The South San Francisco Conference Centre offers versatile meeting spaces with modern amenities near SFO airport. Business travellers appreciate its convenient location and comprehensive event services.
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Learn more about South San Francisco

Perched on the edge of San Francisco Bay, this family-friendly city boasts a surprising castle and stunning mountain views. Foodies flock to local restaurants, while thrill-seekers race go-karts at K1 Speed or tour the famous See's Sweets factory.

See all hotels in South San Francisco
#BVSBlue Aristodes Demetries, One Of Americas Best Known Sculptors Created This Steel Sculpture As A Symbol Of Cabot Cabot And Forbes Industrial Park. Situated 243 Feet Above Sea Level It Rises To A Be Seen From The Bay Bridge, The East Bay and SFO. Called The Wind Harp Locally. It emits eerie sounds when the wind 💨is at its strongest.
Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀
Open Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

Top South San Francisco Hotel Reviews

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

10/10 Excellent
"Very accommodating "
George 2-night trip
Posted 15 hours ago
Holiday Inn Golden Gateway by IHG

More cheap stays in South San Francisco

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

326 S Airport Blvd South San Francisco CA
The price is ฿1,865 per night from 1 Mar to 2 Mar
฿1,865
฿2,234 total
1 Mar - 2 Mar
includes taxes & fees
6/10 (3,234 reviews)

Frequently asked questions

Where is the best place for a stay in South San Francisco?
Home2 Suites by Hilton San Francisco Airport North is a favourite with Expedia customers. This hotel offers free breakfast and in-room kitchenettes. Other top choices based on traveller reviews include Hampton Inn San Francisco Airport and Embassy Suites by Hilton San Francisco Airport Oyster Point. See all available top hotels, or vacation rentals in South San Francisco.
If I need to cancel my hotel reservation in South San Francisco, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in South San Francisco.
What's the best accommodation for a budget-friendly stay in South San Francisco?
Based on reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a popular hotel for our travellers who want a more economical choice, and features free continental breakfast and free Wi-Fi. Other choices for your budget-friendly stay include Hotel Focus SFO and Best Western Plus Grosvenor Airport Hotel. View all budget hotels in South San Francisco.
What's the best family accommodation in South San Francisco?
Embassy Suites by Hilton San Francisco Airport Oyster Point is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Other options to stay with the children include La Quinta Inn & Suites by Wyndham San Francisco Airport N and Inn By The SFO. Also, attractions such as See's Candies and K1 Speed San Francisco are fun for children of all ages. Find more child-friendly accommodations in South San Francisco.
What's the best LGBTQ-friendly accommodation in South San Francisco?
DoubleTree by Hilton San Francisco South Airport Blvd is a top LGBTQ-friendly hotel that features free Wi-Fi and a fitness centre. La Quinta Inn & Suites by Wyndham San Francisco Airport N and Embassy Suites by Hilton San Francisco Airport Oyster Point are other good choices for your stay. See all available hotels listed as LGBTQ-friendly in South San Francisco.
What's the best dog-friendly hotel in South San Francisco?
DoubleTree by Hilton San Francisco South Airport Blvd is a top hotel for people travelling with their pets, and offers a fitness centre and a bar/lounge for its human guests. Two other good options for you and your pet include Embassy Suites by Hilton San Francisco Airport Oyster Point and La Quinta Inn & Suites by Wyndham San Francisco Airport N. See more pet-friendly hotel accommodations in South San Francisco.
What are some hotels with pools in South San Francisco?
Travelodge by Wyndham San Francisco Airport North: Offers complimentary wireless Internet access, a pool and televisions. Embassy Suites by Hilton San Francisco Airport Oyster Point and Holiday Inn Golden Gateway by IHG are two additional hotels that feature an on-site pool. View all hotels with pools in South San Francisco.
How is it to stay in South San Francisco?
Families will find child-friendly activities in South San Francisco, and visitors give high marks for the top-notch restaurants, shopping and local tours. This welcoming city also attracts tourists with its cafes. Top sights around the area include Oracle Park and Pier 39. In South San Francisco, there are 105 hotels and other accommodation options to choose from. Find out more about South San Francisco.
What should I see while I'm in South San Francisco?
Favorite family attractions include See's Candies and K1 Speed San Francisco. Natural beauty is on display at San Bruno Point Park, San Francisco Bay and Santa Cruz Mountains. Additionally, you'll find Oracle Park and Pier 39 in the area. Take a look at what more there is to see and do in Expedia's South San Francisco guide.
How can I get around South San Francisco?
Make your way to South San Francisco Metro Station for metro travel. If you want to venture outside the area, hop on a train at South San Francisco Station. If you want to venture out around the area, you may want a rental car in South San Francisco for your journey.
What's the weather like in South San Francisco?
The hottest months are usually September and August, with an average temperature of 17°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for South San Francisco is 574 mm.