Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

Search Family-Friendly Hotels in South San Francisco

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on South San Francisco Family-Friendly Hotels

Tonight
31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Our top choices for South San Francisco family-friendly hotels

Lobby
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
2.5 star property
The East Side
9.0 out of 10, Wonderful, (441)
"Clean room, helpful staff, complimentary breakfast. "
United States
Veronica
The price is ฿3,523
฿4,129 total
includes taxes & fees
16 Jan - 17 Jan 2026
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
Lobby
Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
South San Francisco
8.4 out of 10, Very good, (1724)
"Great place to stay "
United States
Florence
The price is ฿3,303
฿3,893 total
includes taxes & fees
3 Jan - 4 Jan 2026
Best Western Plus Grosvenor Airport Hotel
Bar (on property)
Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side
8.6 out of 10, Excellent, (1243)
"Everything was just great the amenities the staff the cleanliness the breakfast I had a very relaxing and great time "
United States
Lily
The price is ฿4,617
฿5,421 total
includes taxes & fees
6 Jan - 7 Jan 2026
Embassy Suites by Hilton San Francisco Airport Oyster Point
Exterior
La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (2012)
"Clean room, staff were friendly, breakfast was good, parking was good, overall we're satisfied!"
Canada
Edna
The price is ฿3,182
฿3,738 total
includes taxes & fees
1 Jan - 2 Jan 2026
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Exterior
Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
3.0 star property
The East Side
8.4 out of 10, Very good, (1000)
"nice hotel"
United States
Evangeline
The price is ฿3,328
฿3,904 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hilton Garden Inn San Francisco Arpt North
Lobby
Hotel Nova SFO

Hotel Nova SFO

Hotel Nova SFO
2.5 star property
South San Francisco
8.6 out of 10, Excellent, (1006)
"Great hospitality staff is awesome will definitely stay here again !!"
United States
Cindy
The price is ฿3,114
฿3,652 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Nova SFO
Exterior
Four Points by Sheraton Hotel & Suites San Francisco Airport

Four Points by Sheraton Hotel & Suites San Francisco Airport

Four Points by Sheraton Hotel & Suites San Francisco Airport
3.0 star property
South San Francisco
7.8 out of 10, Good, (999)
"Front desk is perfect"
Mexico
Miguel
The price is ฿2,800
฿3,297 total
includes taxes & fees
4 Jan - 5 Jan 2026
Four Points by Sheraton Hotel & Suites San Francisco Airport
Reception
Travelers Inn

Travelers Inn

Travelers Inn
2.0 star property
South San Francisco
7.6 out of 10, Good, (559)
"Good convenient location, gas station and food shops close to the inn."
United States
Archie
Travelers Inn
Lobby
Rodeway Inn South San Francisco Airport

Rodeway Inn South San Francisco Airport

Rodeway Inn South San Francisco Airport
2.0 star property
South San Francisco
7.0 out of 10, Good, (1000)
"Kind employees and management, quiet and comfortable room"
United States
Michael
The price is ฿2,359
฿2,786 total
includes taxes & fees
1 Jan - 2 Jan 2026
Rodeway Inn South San Francisco Airport
Fridge, microwave, coffee/tea maker, dining tables
Miller Apartments

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (15)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is ฿2,359
฿5,132 total
includes taxes & fees
5 Jan - 6 Jan 2026
Miller Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South San Francisco Hotel Reviews

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

10/10 Excellent
"It was good "
Devyanshi 3-night trip
Posted 18 hours ago
Club Quarters Hotel in San Francisco

Frequently asked questions

What's South San Francisco like for family-friendly holidays?
If you've been thinking about a trip with your children, the welcoming destination of South San Francisco is a good choice. The sightseeing tours, castle and cafes are just a few things that make this an attractive family holiday destination. Fly into San Francisco International Airport (SFO), which is the closest airport, or Oakland, CA (OAK-Oakland Intl.), which is located 11.4 mi (18.3 km) from the city centre.
What's the best family accommodation in South San Francisco?
Best Western Plus Grosvenor Airport Hotel is a hotel with a restaurant and laundry facilities, and it's a top choice on Expedia for families. Other good options to stay with the children include Embassy Suites by Hilton San Francisco Airport Oyster Point and Hilton Garden Inn San Francisco Arpt North.
How many hotels that welcome families will I be able to find in South San Francisco?
Expedia has 8 family-friendly hotels and other accommodation options in South San Francisco.
When's the best time to book a family-friendly holiday in South San Francisco?
The hottest months are usually September and August, with an average temperature of 17°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for South San Francisco is 574 mm.
What's there to see and do with your family in South San Francisco?
While you are visiting South San Francisco, you and the family may want to explore some interesting spots such as See's Candies, K1 Speed San Francisco and Oracle Park. Make sure that you have plenty of time to take in activities in the area such as San Francisco Bay and Pier 39.
What's the best way for us to get around South San Francisco?
Head to South San Francisco Metro Station for metro travel. To venture out into the surrounding area, take a train from South San Francisco Station.