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Top 10 Santa Cruz hotels and places to stay

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Formal dining area with elegant table settings and greenery.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
9.0 out of 10, Wonderful, (323)
"Always an amazing hotel "
The price is ฿3,944
฿3,944 total
31 Aug - 1 Sept
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lido Hotel
Stunning staircase with ornate lion statues and a beautiful artwork above.

Lido Hotel

3.0 star property
9.0 out of 10, Wonderful, (23)
"Clean, with AC and both hot and cold water. "
The price is ฿1,475
฿1,475 total
19 Aug - 20 Aug
Lido Hotel
Ibis Santa Cruz DE LA Sierra
Relax in a comfortable lobby with plush seating, a large plant, and city views.

Ibis Santa Cruz DE LA Sierra

3.0 star property
9.6 out of 10, Exceptional, (47)
"Basic hotel with very friendly staff. The staff is superb Very nice neighborhood!!!nice shopping and great restaurants !"
The price is ฿1,397
฿1,397 total
19 Aug - 20 Aug
Ibis Santa Cruz DE LA Sierra
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Enjoy a panoramic city view from the comfort of your dining area, featuring floor-to-ceiling windows and stylish seating.

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (247)
"Location, surrounding, quietness, good service "
The price is ฿2,431
฿2,431 total
15 Aug - 16 Aug
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Sun Hotel
Relax by the serene pool surrounded by palm trees and enjoy a peaceful evening.

Sun Hotel

3.5 star property
8.2 out of 10, Very good, (305)
"Todo excelente "
Sun Hotel
Camino Real Hotel
Relax by the winding pool surrounded by lush greenery and palm trees.

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (394)
"Great Hotel, had a great time ."
The price is ฿4,526
฿4,526 total
1 Sept - 2 Sept
Camino Real Hotel
Hotel Cortez
Relax in our spacious lobby with a casual dining area, featuring a large potted plant and a flat-screen TV.

Hotel Cortez

3.5 star property
9.0 out of 10, Wonderful, (110)
"I love the pool and garden area and ALL of the staff are so friendly and helpful "
The price is ฿3,724
฿3,724 total
5 Sept - 6 Sept
Hotel Cortez
Novotel Santa Cruz De La Sierra
Relax in our spacious lobby area with a comfortable seating space and expansive windows offering views of the outdoors.

Novotel Santa Cruz De La Sierra

5.0 star property
9.2 out of 10, Wonderful, (95)
"Nice hotel, modern, with pool, good restaurant. Would stay here again without no doubt. "
The price is ฿3,394
฿3,394 total
19 Aug - 20 Aug
Novotel Santa Cruz De La Sierra
Marriott Santa Cruz de la Sierra Hotel
Relax by the rooftop pool with panoramic views of the city skyline.

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
9.0 out of 10, Wonderful, (191)
"Our stay was comfortable and the service was great!"
The price is ฿3,854
฿3,854 total
15 Aug - 16 Aug
Marriott Santa Cruz de la Sierra Hotel
Delfines Collection Hotel By Mercure
Enjoy breathtaking city views from the infinity pool at Delfines Collection Hotel.

Delfines Collection Hotel By Mercure

3.5 star property
9.0 out of 10, Wonderful, (60)
"Excellent place to stay!"
The price is ฿1,503
฿1,503 total
15 Aug - 16 Aug
Delfines Collection Hotel By Mercure
Apart Hotel Premium Suites Santa Cruz
Enjoy the city views from this balcony with a table and two chairs.

Apart Hotel Premium Suites Santa Cruz

3.5 star property
8.6 out of 10, Excellent, (89)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
Apart Hotel Premium Suites Santa Cruz
Hotel LP Santa Cruz Centro
Relax in a spacious room with a large bed, desk, and flat-screen TV, offering a view of the outdoors.

Hotel LP Santa Cruz Centro

3.0 star property
8.0 out of 10, Very good, (280)
"Clean, friendly staff"
Hotel LP Santa Cruz Centro
Hotel LP Equipetrol
Situated in the heart of the city, this hotel offers stunning views from its balcony area.

Hotel LP Equipetrol

3.5 star property
8.2 out of 10, Very good, (198)
"Nice place to stay"
Hotel LP Equipetrol
Swissôtel Santa Cruz De La Sierra
Relax in a serene spa room with a panoramic city view, featuring two treatment beds and a soothing atmosphere.

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (77)
"Beautiful hotel"
The price is ฿2,813
฿2,813 total
19 Aug - 20 Aug
Swissôtel Santa Cruz De La Sierra
Hotel G
Cozy retreat with a kitchenette, featuring a bed, sink, stove, and ample storage.

Hotel G

3.5 star property
7.8 out of 10, Good, (104)
"Excelente Hotel "
Hotel G
Terranova Suites
Relax by the pool surrounded by clean lines and minimalist design.

Terranova Suites

3.5 star property
8.0 out of 10, Very good, (90)
"The pictures of the property have to be from a decade ago. This place it is dirty and in poor shape. "
The price is ฿1,576
฿1,576 total
7 Aug - 8 Aug
Terranova Suites
Premium Suites Deluxe Aparthotel Equipetrol
Relax by the rooftop pool with a stunning city view.

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
9.0 out of 10, Wonderful, (72)
"Good price, great hotel!"
Premium Suites Deluxe Aparthotel Equipetrol
Chairú Eco Hotel
Welcome to ECO HOTEL, where a modern architectural style meets a tropical setting, featuring a prominent entrance with a wooden ceiling and hanging lights.

Chairú Eco Hotel

3.5 star property
9.4 out of 10, Exceptional, (39)
"Nice and clean hotel "
Chairú Eco Hotel
TRYP by Wyndham Santa Cruz
Enjoy breathtaking city views from our rooftop pool, surrounded by a deck with seating.

TRYP by Wyndham Santa Cruz

4.0 star property
9.2 out of 10, Wonderful, (130)
"It should have a dinning room for meals not just breakfast "
The price is ฿3,524
฿3,524 total
15 Aug - 16 Aug
TRYP by Wyndham Santa Cruz
Hotel Puerta del Rey
Swim and relax in the pool surrounded by a deck and lush greenery.

Hotel Puerta del Rey

3.0 star property
5.6 out of 10, (10)
"Simple, clean budget hotel "
Hotel Puerta del Rey
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Santa Cruz

Showing deals for:15 Aug - 17 Aug

Image gallery for Casa Vida

Relax by the serene pool surrounded by lush greenery and palm trees, with a soothing waterfall nearby.

Casa Vida

3.5 star property
Santa Cruz
9.0/10Wonderful (2 reviews)
10% off
Price is ฿3,055
฿6,110 total
Casa Vida
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz
Hamacas map

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Learn more about Santa Cruz

Experience Bolivia as the locals see it in the country’s busiest city, where the museums, public squares and churches give you a glimpse into their everyday lives.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Hotel Maywa

Hotel Maywa

10/10 Excellent
"The hotel was conveniently located within walking distance to shoos, restaurants and attractions. The rooms were clean, spacious and comfortable. The hotel staff were friendly and helped our large group arrange transportation to and from the airport. "
Walter 1-night trip
Posted 3 weeks ago
Hotel Maywa

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is a favourite with Expedia customers. This hotel offers a restaurant and free parking. Reviews from our site also recommend Chairú Eco Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best holiday rentals that Santa Cruz has to offer?

Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop and a microwave. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What's the best budget-friendly accommodation in Santa Cruz?

Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Residencial Ikandire II and Urubo Suite - Hostel. View all budget hotels in Santa Cruz.

What's the best family accommodation in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.

What's the best accommodation for a romantic holiday in Santa Cruz?

Buganvillas Hotel Suites & Spa is a favourite 4-star hotel for couples, and features in-room massages and rainfall showerheads. See all romantic hotels in Santa Cruz.

What's the best LGBTQ-friendly accommodation in Santa Cruz?

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's the best dog-friendly accommodation option in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Hotel LP Santa Cruz Centro and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.

What's the best luxury accommodation option in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia and Camino Real Hotel are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.

What's the best boutique-style hotel in Santa Cruz?

Senses Boutique Hotel is a favourite 3.5-star hotel with our travellers looking for stylish accommodation, and features 52 guestrooms, 3 restaurants and a bar.

What are some accommodation options with pools in Santa Cruz?

Sun Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. A couple of other options that feature an on-site pool include Buganvillas Hotel Suites & Spa and Yotau All Suites Hotel. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

What's it like to stay in Santa Cruz?

Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 268 hotels and other accommodation options to choose from. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Cultural venues include Cine Center, Sacred Art Museum and Franco Aleman Cultural Center. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Catedral de Santa Cruz might be worth a visit. The picturesque setting of Guembe Biocenter and Lomas de Arena Regional Park exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

How should I get around Santa Cruz?

If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the weather like in Santa Cruz?

The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.