A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Check prices for these dates

Next weekend
17 Jul - 19 Jul
In two weeks
24 Jul - 26 Jul

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Star rating

Our top choices for Santa Cruz hotels

Outdoor pool

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (386 reviews)
"Very well located three start hotel. Clean with everything you need for an in/out night. Hotel needs a redoing."
United States
jose
The price is ฿3,596
฿3,596 total
16 Jul - 17 Jul
Sun Hotel
Exterior

Surbackpackers

Surbackpackers
3.0 star property
Santa Cruz
The price is ฿749
฿749 total
14 Jul - 15 Jul
Surbackpackers
Outdoor pool

Mirador del Cielo

Mirador del Cielo
3.0 star property
Santa Cruz
4.0 out of 10, (1 review)
The price is ฿863
฿863 total
13 Jul - 14 Jul
Mirador del Cielo
Reception

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (46 reviews)
"Lovely stay for a night. Great location within easy walking distance to the center."
United States
Gabrielle
The price is ฿1,259
฿1,259 total
13 Jul - 14 Jul
Lido Hotel
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (109 reviews)
"Great Location"
United States
Blanca
The price is ฿1,531
฿1,531 total
14 Jul - 15 Jul
Premium Suites Deluxe Aparthotel Equipetrol
Honeymoon Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (52 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ฿1,553
฿2,053 total
19 Jul - 20 Jul
HOTEL OSHO
Outdoor pool, pool loungers

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (144 reviews)
"Lovely hotel. Great room, location, staff and amenities. "
Norway
Solvei Emily Brekke
The price is ฿4,075
฿4,075 total
18 Jul - 19 Jul
Hotel Cortez
Front of property

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (69 reviews)
"Clean room and friendly staff "
United States
marcia
The price is ฿1,798
฿1,798 total
14 Jul - 15 Jul
Chairú Eco Hotel
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (279 reviews)
"The hotel truly exceeded all my expectations. The quality of the facilities, the service, and the excellent breakfast were outstanding."
United States
imilse de
The price is ฿2,450
฿2,450 total
1 Aug - 2 Aug
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Living area

Posada Express Fast Check

Posada Express Fast Check
3.0 star property
Santa Cruz
8.0 out of 10, Very good, (8 reviews)
"The posada expres was closed and "
United States
Marcelo
The price is ฿1,498
฿1,648 total
13 Jul - 14 Jul
Posada Express Fast Check
Terrace/patio

Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
8.0 out of 10, Very good, (19 reviews)
"Very clean room and great staff"
Canada
Stanley
The price is ฿1,152
฿1,152 total
14 Jul - 15 Jul
Hotel Las Américas
Double Room, 1 Queen Bed | Premium bedding, down duvets, minibar, blackout curtains

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (107 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is ฿1,194
฿1,194 total
12 Aug - 13 Aug
Hotel G
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
The price is ฿1,655
฿1,655 total
13 Jul - 14 Jul
Equipetrol Suites Apart Hotel
Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (133 reviews)
"Everything was excellent! Clean room, delicious food, friendly staff, great location!"
United States
Heidi
The price is ฿3,023
฿3,023 total
19 Jul - 20 Jul
Cosmopolitano Hotel Boutique
1 bedroom, in-room safe, desk, iron/ironing board

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (102 reviews)
"Great location."
United States
Ruben
The price is ฿899
฿899 total
14 Jul - 15 Jul
Apart Hotel Premium Suites Santa Cruz
Reception

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (433 reviews)
"Definitely I would’ve recommend anybody who is looking for hotel because the service was excellent make me feel special since I walked in into the place and also I was impressed how clean the place was…Thanks for the service guys…Keep up this way..thanks again for everything…I’ll see you soon.🙏"
United States
Edwin
The price is ฿4,830
฿4,830 total
11 Aug - 12 Aug
Camino Real Hotel
Miscellaneous

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (124 reviews)
"Nice place"
United States
Juan Carlos
The price is ฿1,780
฿1,780 total
1 Aug - 2 Aug
Ibis Santa Cruz DE LA Sierra
Bar (on property)

Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very good, (91 reviews)
"Easy to access"
United States
Dorothy
The price is ฿1,728
฿1,728 total
13 Jul - 14 Jul
Terranova Suites
Seasonal outdoor pool

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (385 reviews)
"Nice hotel"
United States
Mabel Marisel
The price is ฿4,217
฿4,217 total
19 Jul - 20 Jul
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Daily buffet breakfast for a fee

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (209 reviews)
"Nice place to stay"
United States
Ricardo
The price is ฿1,308
฿1,474 total
17 Jul - 18 Jul
Hotel LP Equipetrol
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Holiday Rentals in Santa Cruz

Aparthotel
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (109 reviews)
"Great Location"
Premium Suites Deluxe Aparthotel Equipetrol
See all holiday rentals
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
See properties

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A colonial-style building with a bell tower, palm trees, and a paved walkway.

Top Santa Cruz Hotel Reviews

Hotel Las Américas

Hotel Las Américas

10/10 Excellent
"Lo mejor es la ubicación"
José 3-night trip
Posted 2 days ago
Hotel Las Américas

More cheap stays in Santa Cruz

Ibiza Hostel

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz
The price is ฿419 per night from 13 Jul to 14 Jul
฿419
฿886 total
13 Jul - 14 Jul

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveller data. This hotel offers a restaurant and free parking. Other good choices for your stay include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Ibiza Hostel and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Casa Por Temporadas is a top dog-friendly guest house, and offers an outdoor pool along with in-room kitchens for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Swissôtel Santa Cruz De La Sierra. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Novotel Santa Cruz De La Sierra are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Yotau All Suites Hotel is a top hotel with 2 outdoor swimming pools, a children's pool and 2 restaurants. A couple of other options that feature an on-site pool include Buganvillas Hotel Suites & Spa and Royal Lodge Hotel. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 292 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Cine Center, Ethno-folkloric Museum and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.