Santa Cruz Holiday Rentals, Santa Cruz: Private House Rentals

A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Our top choices for Santa Cruz hotels

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

A rooftop pool area with a view of the city skyline at dusk.

A modern lounge area with leather sofas, a coffee table, and a view of a green wall with plants.

1. TRYP by Wyndham Santa Cruz

Equipetrol

Matias

฿3,655

฿3,655 total

12 Oct - 13 Oct

A poolside area with lounge chairs and a palm tree.

A pathway through a lush garden with various trees and shrubs.

A dining table with breakfast items and a pool view.

A banquet hall with long tables, chandeliers, and draped curtains.

2. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

Daniel

฿4,532

฿4,532 total

7 Nov - 8 Nov

A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

A hotel with a prominent 'Hampton' sign, large windows, and a modern facade.

A hotel room with a large bed, a desk, a chair, a telephone, and a view of the city through large windows.

A modern hotel lobby with a bar area, seating arrangements, and a television.

3. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

Scott

฿2,468

฿2,468 total

15 Oct - 16 Oct

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious lobby with a curved reception desk, multiple seating areas, and a bar.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

4. Sun Hotel

Santa Cruz

Ivan

฿3,621

฿3,621 total

12 Oct - 13 Oct

A modern lobby with seating areas, a coffee table, and a large potted plant.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

5. Ibis Santa Cruz DE LA Sierra

Equipetrol

Hui Hua

฿1,331

฿1,331 total

25 Oct - 26 Oct

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

A restaurant with a long counter, dark chairs, and hanging lights.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

6. Camino Real Hotel

Santa Cruz

Wendy

฿5,841

฿5,841 total

30 Oct - 31 Oct

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

7. Lido Hotel

Centro Histórico

Gabrielle

฿842

฿842 total

15 Oct - 16 Oct

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel with a unique wavy facade, multiple parking spaces, and a clear blue sky.

A buffet setup with various food items and a serving area.

A hotel room with two beds, a desk, a television, and a small kitchenette.

8. Hotel Las Américas

Centro Histórico

Stanley

฿875

฿875 total

12 Oct - 13 Oct

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A buffet with various fruits and snacks.

9. Hotel Cortez

Equipetrol

Rigoberto

฿4,345

฿4,345 total

7 Nov - 8 Nov

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

10. HOTEL OSHO

Santa Cruz

David

฿1,693

฿1,693 total

23 Oct - 24 Oct

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

A modern lobby with a dining area, sofas, and a decorative wall.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

11. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

Deivis

฿3,547

฿3,547 total

7 Nov - 8 Nov

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A modern outdoor pool area with a red brick wall, a large mural, and outdoor furniture.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

12. Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

Elizabeth

฿3,615

฿3,615 total

16 Oct - 17 Oct

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A reception desk with a wooden panel wall behind it, displaying the text "Premium Suites".

A group of women standing in a modern interior with wooden paneling and a reception desk.

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

13. Apart Hotel Premium Suites Santa Cruz

Santa Cruz

Ruben

฿905

฿905 total

12 Oct - 13 Oct

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

A room with a large window, a brick wall, and a hanging plant.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

14. Chairú Eco Hotel

Santa Cruz

Luis

฿1,584

฿1,584 total

1 Nov - 2 Nov

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A building with a sign that reads "COSMOPOLITANO."

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

15. Cosmopolitano Hotel Boutique

Centro Histórico

Rajendra

฿1,786

฿1,786 total

27 Oct - 28 Oct

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A modern staircase with glass railings, leading to a landing with a small garden area.

A buffet setup with various food items, including pastries, a cake, and beverages.

A modern lobby with wooden paneling, two grey sofas, and pendant lighting.

16. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

Luisa

฿1,542

฿1,542 total

18 Oct - 19 Oct

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

17. Hotel G

Santa Cruz

JACOB

฿920

฿920 total

9 Nov - 10 Nov

A rooftop pool with a glass barrier reflecting the sunset and city skyline.

A buffet with various food items and a pitcher of orange juice.

An outdoor dining area with tables and chairs, a wooden pergola with hanging lights, and a city view.

A modern building with a stone facade and large windows. The name 'DEFINES COLLECTION' is prominently displayed on the building.

18. Delfines Collection Hotel By Mercure

Equipetrol

ALEJANDRO

฿1,599

฿1,599 total

25 Oct - 26 Oct

19. Hotel Maywa

Santa Cruz

Alex

฿1,477

฿1,477 total

12 Oct - 13 Oct

A hotel room with a round wooden table, two single beds, a red chair, and a wooden wall.

A compact kitchenette with a refrigerator, a coffee maker, and a small table with a laptop.

A spacious living area with a black sofa, a glass coffee table, and a plant.

A hotel room with a bed, a desk with a computer and two remote controls, a window with a city view, and a wooden headboard.

20. Hotel Pascana centro

Centro Histórico

฿2,414

฿2,414 total

12 Oct - 13 Oct

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Holiday Rentals in Santa Cruz

Apartment

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

"Great location."

Aparthotel

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

"great place to stay!"

Apartment

A modern rooftop pool with a city view, wooden flooring, and a seating area.

A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.

A modern hotel room with a bed, bedside table, and a desk with a chair.

A modern kitchen with a built-in grill, a black countertop, and a wall mural of tropical leaves.

AMERICA APARTMENTS

Santa Cruz

"Clean room, great staff "

Aparthotel

An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

A hotel room with a bed, a sofa, a coffee table, and a vase of flowers.

A modern hotel with a swimming pool, lounge chairs, and a clear sky.

A kitchen with granite countertops, wooden chairs, a microwave, and a window.

Terranova Suites

Santa Cruz

"Easy to access"

Aparthotel

A modern hotel room with a bed, a nightstand, a lamp, a painting, a kitchen area, and a bathroom.

A hotel reception area with a reception desk, a waiting area with a chair and ottoman, and an elevator.

A cozy seating area with a round wooden table, a white cup, and a book.

A modern kitchen with wooden cabinets, a black countertop, and a built-in stove.

Equipetrol Suites Apart Hotel

Santa Cruz

"Perfect hotel"

Aparthotel

A hotel with multiple floors, a pool area with lounge chairs, and palm trees.

A modern dining area with a glass table and striped chairs, a white tablecloth, and a view of a kitchen and bar area.

A room with a central square area surrounded by lush green foliage, white walls, and a wooden floor.

A tropical garden with a wooden deck, a hot tub, and lush greenery.

Apart Hotel Toborochi

Equipetrol

"Very comfortable and quiet place and very good location. "

Holiday Home

A swimming pool with a waterfall feature, surrounded by lush greenery and palm trees.

Casa Vida

Santa Cruz

"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.Learn more about Santa Cruz

Equipetrol

When in Equipetrol, you can plan a visit to Santa Cruz Zoo and Municipal Library, some noteworthy sights in the nearby area.

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Centro Histórico

If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.

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Hamacas

When in Hamacas, you can plan a visit to Las Brisas Shopping Center and Santa Cruz Zoo, some noteworthy sights in the nearby area.

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Zona Sur (South Zone)

Though Zona Sur (South Zone) may not have many top sights, you can venture to the surrounding area to see attractions like Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre.

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Urubó

While there might not be top attractions in Urubó, you can explore the larger area and discover places like Guembe Biocenter and Ventura Mall.

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Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.

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A historic tower with a clock, surrounded by lush greenery and palm trees.

San Lorenzo Cathedral

9.0/10 (84 reviews)

This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.

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Ventura Mall

9.0/10 (183 reviews)

Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.

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Guembe Biocenter

8.8/10 (60 reviews)

This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.

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Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernised facilities and vibrant Santa Cruz culture.

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Las Brisas Shopping Center

8.4/10 (40 reviews)

This modern complex offers 80+ stores, a nine-screen cinema, and a unique outdoor restaurant promenade. Explore the gastronomic boulevard for dining experiences beyond the standard food court options.

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Santa Cruz Zoo

8.4/10 (53 reviews)

The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.

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Blacutt Square

8.2/10 (19 reviews)

Plaza Blacutt offers a verdant escape in Santa Cruz with mature trees shading tiled pathways. Enjoy local flavours from vendors along the northern edge while children play in the well-equipped playground areas.

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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

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A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Top Santa Cruz Hotel Reviews

Hotel Cortez

10/10 Excellent

"Most amazing hotel staff ever. Thanks for making this a special stay. good food, but the staff goes the extra mile to make it special. Gracias!!"

HOTEL OSHO

10/10 Excellent

"Todo muy bueno excelente regresare"

Sun Hotel

8/10 Good

"A super convenient hotel with spacious rooms and nice grounds. Perfect for a layover on long flights Shuttle service great. Loved our balcony overlooking the pool , sitting with a cup of tea listening to the birds and chilling before a long flight home"

TRYP by Wyndham Santa Cruz

10/10 Excellent

"."

Lido Hotel

10/10 Excellent

"Very convenient place to stay Clean and very affordable Good staff"

Chairú Eco Hotel

8/10 Good

"The breakfast was not that good, but everything was good"

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent

"The room was very clean and the breakfast was fantastic. Overall it was a great experience."

Novotel Santa Cruz De La Sierra

10/10 Excellent

"All around good price and location"

Delfines Collection Hotel By Mercure

10/10 Excellent

"Todo muy bien"

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz

฿1,724

฿1,724 total

12 Oct - 13 Oct

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz

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Amaca Hostal

249 Independencia Santa Cruz Departamento de Santa Cruz

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Casa Por Temporadas

Barrio Las Pampitas, calle 3 Nro. 99 Santa Cruz Santa Cruz Department

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10/10 Exceptional! (1 review)

HOTEL CASA BLANCA

Avenida Marcelo Terceros Zona Equipetrol Santa Cruz Santa Cruz de la Sierra

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Hotel Viru Viru II

Av. Alameda 72 - Zona Valle Sanchez Santa Cruz Santa Cruz de la Sierra

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4.8/10 (3 reviews)

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveller data. This hotel offers a restaurant and free parking. Other good choices for your stay include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best holiday rentals that Santa Cruz has to offer?

Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What's the best budget-friendly accommodation in Santa Cruz?

Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Residencial Ikandire II and Nomad Hostel. View all budget hotels in Santa Cruz.

What's the best family accommodation in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.

What's the best LGBTQ-friendly accommodation in Santa Cruz?

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Hotel Pascana centro and Swissôtel Santa Cruz De La Sierra are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's the best dog-friendly accommodation option in Santa Cruz?

Casa Por Temporadas is a top dog-friendly guest house, and offers an outdoor pool along with in-room kitchens for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.

What's the best luxury accommodation option in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.

What are some accommodation options with pools in Santa Cruz?

Yotau All Suites Hotel is a top hotel with 2 outdoor swimming pools, a children's pool and 2 restaurants. A couple of other options that feature an on-site pool include Gran Hotel Santa Cruz and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

What's the best hotel in Santa Cruz with an on-site water park or a water park nearby?

Gran Hotel Santa Cruz is a popular hotel, featuring free water park access, an outdoor pool and a restaurant. Take a look at all hotels with or near waterparks in Santa Cruz.

What's it like to stay in Santa Cruz?

Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 312 hotels and other accommodation options to choose from. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Cultural venues include Ethno-folkloric Museum, Cine Center and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

How should I get around Santa Cruz?

If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the weather like in Santa Cruz?

The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.

Find hotels in Santa Cruz from ฿543

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Cruz

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Cruz hotels

1. TRYP by Wyndham Santa Cruz

2. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4. Sun Hotel

5. Ibis Santa Cruz DE LA Sierra

6. Camino Real Hotel

7. Lido Hotel

8. Hotel Las Américas

9. Hotel Cortez

10. HOTEL OSHO

11. Marriott Santa Cruz de la Sierra Hotel

12. Alfonsina Hotel Boutique by Inboccaluppo

13. Apart Hotel Premium Suites Santa Cruz

14. Chairú Eco Hotel

15. Cosmopolitano Hotel Boutique

16. Premium Suites Deluxe Aparthotel Equipetrol

17. Hotel G

18. Delfines Collection Hotel By Mercure

19. Hotel Maywa

20. Hotel Pascana centro

Holiday Rentals in Santa Cruz

Apart Hotel Premium Suites Santa Cruz

Premium Suites Deluxe Aparthotel Equipetrol

AMERICA APARTMENTS

Terranova Suites

Equipetrol Suites Apart Hotel

Apart Hotel Toborochi

Casa Vida

Where to stay in Santa Cruz

Equipetrol

Centro Histórico

Hamacas

Zona Sur (South Zone)

Urubó

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

San Lorenzo Cathedral

Ventura Mall

Guembe Biocenter

Ramon Tahuichi Aguilera Stadium

Las Brisas Shopping Center

Santa Cruz Zoo

Blacutt Square

Learn more about Santa Cruz

Top Santa Cruz Hotel Reviews

Hotel Cortez

HOTEL OSHO

Sun Hotel

TRYP by Wyndham Santa Cruz

Lido Hotel

Chairú Eco Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Novotel Santa Cruz De La Sierra

Delfines Collection Hotel By Mercure

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Ibiza Hostel

Amaca Hostal

Casa Por Temporadas

HOTEL CASA BLANCA

Hotel Viru Viru II

Frequently asked questions

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