Find hotels in Santa Cruz from ฿1,141

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top 10 Santa Cruz hotels and places to stay

Ibis Santa Cruz DE LA Sierra
3.0 star property
9.6 out of 10, Exceptional, (65)
"Predictable, good vibe. Very good bed."
United States
Ted
The price is ฿1,141
฿1,141 total
1 Dec - 2 Dec
Ibis Santa Cruz DE LA Sierra
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
9.0 out of 10, Wonderful, (337)
"Los Tajibos is perhaps the best place to stay in Santa Cruz."
United States
Miguel
The price is ฿4,529
฿4,529 total
1 Dec - 2 Dec
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Sun Hotel
3.5 star property
8.4 out of 10, Very good, (322)
"The rooms were very nice and the breakfast was good with helpful staff in the breakfast area during my short stay"
United States
Brian
The price is ฿2,905
฿2,905 total
1 Nov - 2 Nov
Sun Hotel
Hotel Cortez
3.5 star property
9.2 out of 10, Wonderful, (116)
"The staff and property are second to none! "
United States
Cynthia
The price is ฿3,849
฿3,849 total
8 Nov - 9 Nov
Hotel Cortez
Lido Hotel
3.0 star property
9.0 out of 10, Wonderful, (28)
"I really liked the Lido hotel and the people running it. They were very kind and accommodating. And I wish them the best of everything."
United States
Anonymous traveller
The price is ฿1,477
฿1,477 total
26 Nov - 27 Nov
Lido Hotel
Camino Real Hotel
4.5 star property
8.8 out of 10, Excellent, (404)
"Great location Great hotel"
United States
Sergio
The price is ฿4,982
฿4,982 total
25 Nov - 26 Nov
Camino Real Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
9.2 out of 10, Wonderful, (251)
"Nice hotel "
United States
Narciso Lorenzo
The price is ฿2,385
฿2,385 total
13 Nov - 14 Nov
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Marriott Santa Cruz de la Sierra Hotel
5.0 star property
9.0 out of 10, Wonderful, (204)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ฿3,597
฿3,597 total
28 Nov - 29 Nov
Marriott Santa Cruz de la Sierra Hotel
Delfines Collection Hotel By Mercure
3.5 star property
9.0 out of 10, Wonderful, (68)
"Clean comfortable rooms "
United States
mary
The price is ฿1,504
฿1,504 total
29 Nov - 30 Nov
Delfines Collection Hotel By Mercure
Apart Hotel Premium Suites Santa Cruz
3.5 star property
8.6 out of 10, Excellent, (93)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
United States
Andrew
Apart Hotel Premium Suites Santa Cruz
Novotel Santa Cruz De La Sierra
5.0 star property
9.2 out of 10, Wonderful, (102)
"Nice hotel, modern, with pool, good restaurant. Would stay here again without no doubt. "
United States
Juan Pablo
The price is ฿3,397
฿3,397 total
29 Nov - 30 Nov
Novotel Santa Cruz De La Sierra
TRYP by Wyndham Santa Cruz
4.0 star property
9.2 out of 10, Wonderful, (140)
"Nice stay with good service "
United States
Jianyuan
The price is ฿3,203
฿3,203 total
1 Dec - 2 Dec
TRYP by Wyndham Santa Cruz
Hotel LP Santa Cruz Centro
3.0 star property
8.0 out of 10, Very good, (280)
"Best 👍"
United States
Chaudhary
Hotel LP Santa Cruz Centro
HOTEL OSHO
3.5 star property
9.0 out of 10, Wonderful, (28)
"The staff was excellent, Managment was extremely attentive. Easy location. "
United States
Emelyn
The price is ฿1,896
฿1,896 total
1 Nov - 2 Nov
HOTEL OSHO
Chairú Eco Hotel
3.5 star property
9.4 out of 10, Exceptional, (41)
"Nice and clean hotel "
United States
Luis
Chairú Eco Hotel
Swissôtel Santa Cruz De La Sierra
4.5 star property
9.2 out of 10, Wonderful, (79)
"Beautiful hotel"
Australia
Joanna
The price is ฿4,788
฿4,788 total
25 Nov - 26 Nov
Swissôtel Santa Cruz De La Sierra
Hotel Las Américas
3.0 star property
6.0 out of 10, (1)
"O chuveiro foi impossível tomar um.banho de qualidade "
Brazil
Jean
The price is ฿1,243
฿1,243 total
2 Nov - 3 Nov
Hotel Las Américas
Hotel LP Equipetrol
3.5 star property
8.2 out of 10, Very good, (201)
"Overall it was a good expereience."
United States
Jeferson
Hotel LP Equipetrol
Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
9.0 out of 10, Wonderful, (77)
"Good price, great hotel!"
United States
James
Premium Suites Deluxe Aparthotel Equipetrol
Hotel G
3.5 star property
7.8 out of 10, Good, (104)
"Very nice, clean and confortable. People very nice and god breakfast"
United States
Yasmín
Hotel G
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Santa Cruz

Showing deals for:7 Nov - 9 Nov
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a favourite with Expedia customers. This hotel offers a restaurant and free parking. Reviews from our site also recommend Chairú Eco Hotel and Alfonsina Hotel Boutique by Inboccaluppo as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Urubo Suite - Hostel and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Hotel LP Santa Cruz Centro and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia and Camino Real Hotel are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. A couple of other options that feature an on-site pool include Buganvillas Hotel Suites & Spa and Yotau All Suites Hotel. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness centre, tennis courts and a bar. Spend an afternoon at Hotel Spa where you'll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 275 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Cine Center, Ethno-folkloric Museum and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. The picturesque setting of Guembe Biocenter and Lomas de Arena Regional Park exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.