A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Our top choices for Santa Cruz LGBT-friendly hotels

1. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (289 reviews)
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
United States
Scott
The price is ฿2,486
฿2,486 total
30 Oct - 31 Oct
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

2. Gran Hotel Santa Cruz

Gran Hotel Santa Cruz
4.5 star property
Centro Histórico
The price is ฿1,884
฿1,884 total
29 Oct - 30 Oct
Gran Hotel Santa Cruz

3. Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (90 reviews)
"Great room, spacious, quiet and the shower was great"
United States
GONZALO
The price is ฿4,432
฿4,432 total
16 Nov - 17 Nov
Swissôtel Santa Cruz De La Sierra

4. Hotel Pascana centro

Hotel Pascana centro
3.5 star property
Centro Histórico
9.0 out of 10, Wonderful, (2 reviews)
"El hotel se encuentra en el Centro histórico de la ciudad, es una estructura dentro del marco historico de la ciudad, pero se encuentra en buenas condiciones. Con facil acceso al transporte. Camina el centro de la ciudad histórica con tranquilidad."
United States
Miguel
The price is ฿2,584
฿2,584 total
29 Oct - 30 Oct
Hotel Pascana centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

Searching for a gay-friendly hotel in Santa Cruz?
Whether you are travelling with your partner or flying solo, you'll find gay-friendly hotels in Santa Cruz on Expedia. Visitors are sure to enjoy all Santa Cruz has to offer including its shopping.
What is the top LGBTQ-friendly place to stay in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Hotel Pascana centro and Swissôtel Santa Cruz De La Sierra are two other good options for your stay.
How many gay-friendly accommodation options will I find in Santa Cruz?
There are currently 4 LGBTQ-friendly accommodation options in Santa Cruz.
What should I see while I'm in Santa Cruz?
During your trip, get out and enjoy everything Santa Cruz has to offer. You and your travelling companions may want to visit Plaza 24 de Septiembre, Blacutt Square and Ramon Tahuichi Aguilera Stadium. While you're here, create some great memories of your trip with stops at Santa Cruz Zoo, Ventura Mall and Las Brisas Shopping Center.
What is an LGBTQ-friendly hotel in Santa Cruz?
LGBTQ-friendly hotels welcome all travellers who identify as LGBTQIA+. We have worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of gay-friendly hotels worldwide. In Santa Cruz, hotels affiliated with IGLTA operate in a spirit of inclusiveness, prioritising a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.
What can I expect from an LGBTQ-friendly Santa Cruz hotel?
Stay at a gay-friendly hotel in Santa Cruz and you won't have to hide or your sexuality or your gender identity when you check in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer wedding ceremonies and honeymoon packages for same-sex couples.