Lodging Image

Find the best Santa Cruz Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Santa Cruz Accommodation: Most Popular Cities to Stay

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Star rating

Our top choices for Santa Cruz hotels

Casa Por Temporadas

Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
United States
Cynthia
Casa Por Temporadas

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (381 reviews)
"Nice hotel"
United States
Mabel Marisel
The price is ฿4,213
฿4,213 total
29 Jun - 30 Jun
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (107 reviews)
"Great Location"
United States
Blanca
The price is ฿1,530
฿1,530 total
27 Jun - 28 Jun
Premium Suites Deluxe Aparthotel Equipetrol

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (236 reviews)
"Amazing hotel"
United States
Deivis
The price is ฿4,065
฿4,065 total
3 Jul - 4 Jul
Marriott Santa Cruz de la Sierra Hotel

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (381 reviews)
"Very well located three start hotel. Clean with everything you need for an in/out night. Hotel needs a redoing."
United States
jose
The price is ฿3,593
฿3,593 total
27 Jun - 28 Jun
Sun Hotel

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (428 reviews)
"Definitely I would’ve recommend anybody who is looking for hotel because the service was excellent make me feel special since I walked in into the place and also I was impressed how clean the place was…Thanks for the service guys…Keep up this way..thanks again for everything…I’ll see you soon.🙏"
United States
Edwin
The price is ฿5,246
฿5,246 total
28 Jun - 29 Jun
Camino Real Hotel

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (123 reviews)
"Nice place"
United States
Juan Carlos
The price is ฿1,779
฿1,779 total
14 Jul - 15 Jul
Ibis Santa Cruz DE LA Sierra

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (68 reviews)
"Clean room and friendly staff "
United States
marcia
The price is ฿1,796
฿1,796 total
1 Jul - 2 Jul
Chairú Eco Hotel

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (118 reviews)
"REALLY NICE HOTEL. STAFF WONDERFULL"
United States
ERNESTO
The price is ฿4,561
฿4,561 total
18 Jul - 19 Jul
Novotel Santa Cruz De La Sierra

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (144 reviews)
"Lovely hotel. Great room, location, staff and amenities. "
Norway
Solvei Emily Brekke
The price is ฿4,072
฿4,072 total
3 Jul - 4 Jul
Hotel Cortez

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (102 reviews)
"Great location."
United States
Ruben
The price is ฿898
฿898 total
26 Jun - 27 Jun
Apart Hotel Premium Suites Santa Cruz

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (44 reviews)
"Beautiful place, wonderful artwork"
United States
Elizabeth
The price is ฿3,586
฿3,586 total
26 Jun - 27 Jun
Alfonsina Hotel Boutique by Inboccaluppo

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (51 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ฿1,552
฿2,051 total
30 Jun - 1 Jul
HOTEL OSHO

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (279 reviews)
"The hotel truly exceeded all my expectations. The quality of the facilities, the service, and the excellent breakfast were outstanding."
United States
imilse de
The price is ฿2,449
฿2,449 total
16 Jul - 17 Jul
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
7.8 out of 10, Good, (14 reviews)
"Very clean room and great staff"
Canada
Stanley
The price is ฿1,151
฿1,151 total
26 Jun - 27 Jun
Hotel Las Américas

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (164 reviews)
"My go too hotel whenever I'm in town! "
United States
Pluetina
The price is ฿3,264
฿3,264 total
26 Jun - 27 Jun
TRYP by Wyndham Santa Cruz

Prince Hotel

Prince Hotel
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (6 reviews)
"Nice place "
United States
Marco
The price is ฿1,118
฿1,683 total
10 Jul - 11 Jul
Prince Hotel

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (95 reviews)
"Great location, nice and quiet neighborhood."
United States
ALEJANDRO
The price is ฿1,675
฿1,675 total
30 Jun - 1 Jul
Delfines Collection Hotel By Mercure

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (209 reviews)
"Nice place to stay"
United States
Ricardo
The price is ฿1,377
฿1,543 total
3 Jul - 4 Jul
Hotel LP Equipetrol

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (107 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is ฿1,449
฿1,449 total
5 Jul - 6 Jul
Hotel G
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Santa Cruz

Showing deals for:3 Jul - 5 Jul

Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Guide to exploring Santa Cruz

Top reasons to visit Santa Cruz

  • Cultural Vibrancy: Santa Cruz boasts a lively atmosphere, rich in culture, with bustling markets and music venues to explore.
  • Outdoor Adventures: The city offers access to national parks and exciting water parks, perfect for thrill-seekers.
  • Architectural Marvels: Visitors can admire stunning cathedrals and vibrant squares that showcase the city’s heritage.
  • Family-Friendly Activities: There are numerous family-oriented attractions that cater to all ages, ensuring fun for everyone.
  • Diverse Accommodation: Santa Cruz offers a range of lodging options, from luxurious hotels to charming bed and breakfasts.

Find great hotels in Santa Cruz

Discover a variety of accommodation options in Santa Cruz, Bolivia, catering to every traveller's needs. From luxurious hotels to charming bed and breakfasts, you’ll find places that prioritise business amenities, family-friendly environments, and pet-friendly policies. Whether you seek a comfortable stay for your holiday or a sophisticated experience for business, Santa Cruz offers a range of hotels with excellent reviews and convenient locations, making it an ideal destination for all visitors.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: Situated in the heart of Santa Cruz, Los Tajibos offers a unique blend of family-friendly and spa-themed experiences. With a commendable 3.5-star rating and a guest rating of 9.0, this hotel is ideal for those seeking relaxation and comfort. The property features a full spa service with a variety of treatments including body scrubs and aromatherapy sessions, alongside an outdoor seasonal pool. Families will appreciate amenities such as a First Aid Kit for peace of mind, making it a wonderful choice for both leisure and business travellers.
  • Marriott Santa Cruz de la Sierra Hotel: As a luxurious 5-star hotel, the Marriott Santa Cruz de la Sierra is known for its upscale offerings and attentive service, reflected in its high guest rating of 9.0. This property is perfect for those desiring a lavish family getaway. The hotel boasts an outdoor pool, accessible facilities, and a soothing spa featuring massages and treatments designed for ultimate relaxation. Amenities for children, such as free cribs, ensure that families are well catered for, enhancing the comfort of your stay.
  • Camino Real Hotel: With a solid 4-star rating and a guest rating of 9.0, Camino Real Hotel stands out for its family-oriented and spa-themed atmosphere. Guests can enjoy a range of on-site facilities, including a sauna, outdoor pool, and dedicated children's amenities such as a shared playground and babysitting services. The hotel also features a swim-up bar and couples treatment rooms for those looking to unwind together, making it a well-rounded option for both families and couples seeking relaxation.

Where to stay in Santa Cruz

Santa Cruz, Bolivia, offers a delightful blend of culture and natural beauty, perfect for family getaways and urban exploration. Wander through the vibrant streets of Santa Cruz city, bask in the sunny weather, and enjoy excursions that reveal the region's rich cultural heritage. Nearby, the serene beaches and lush landscapes provide a tropical escape. Whether you seek seclusion or urban excitement, Santa Cruz promises memorable experiences for every traveller.

  • Santa Cruz: As the largest city in Bolivia, Santa Cruz offers a vibrant mix of urban culture and natural beauty. Nestled in the eastern lowlands, it serves as a gateway to the Amazon Basin. Visitors can indulge in shopping at modern malls or relax at local resorts. Key attractions include the picturesque piazza square, the lush botanical garden, and the impressive cathedral. With a steady flow of tourists year-round, and peaks in January, July, and September, Santa Cruz is perfect for families and culture enthusiasts seeking a lively city experience.
  • Samaipata: Located about 120 kilometres from Santa Cruz, Samaipata is a charming town renowned for its stunning landscapes and adventure opportunities. Set in the foothills of the Andes, it’s a hotspot for outdoor lovers, offering hiking trails that showcase breathtaking scenery. Attractions such as the archaeological site and historic landmarks make it an enriching destination. With consistent visitor numbers, particularly in January and during the July to September peak season, Samaipata is an ideal escape for those looking to immerse themselves in nature and Bolivian history.
  • Montero: Just a short drive from Santa Cruz, Montero is a bustling city that embodies Bolivian culture. Known for its rich traditions and vibrant community life, it attracts travellers seeking a genuine cultural experience. The local piazza square serves as a focal point for social gatherings and events. While not as crowded as Santa Cruz, Montero sees an influx of visitors particularly in January and during the September to October period, making it a worthwhile stop for those looking to dive deeper into Bolivia’s urban essence.

Things to do in Santa Cruz

Shopping

At Ventura Mall, you can explore a variety of shops offering both local and international brands, while the Feria Barrio Lindo market showcases vibrant handicrafts and traditional Bolivian souvenirs. Each location provides a unique glimpse into the culture and creativity of Santa Cruz.

Recreation

Wellness Retreat Spa offers a tranquil environment with therapeutic massages and holistic treatments, allowing guests to unwind and rejuvenate. Nearby, the Biocentro Guembe is a lush nature reserve, ideal for leisurely walks among exotic fauna and flora, alongside refreshing pools for a revitalising dip.

Adventure

In Santa Cruz, explore the lush Amboró National Park, where you can hike through diverse ecosystems and spot unique wildlife. For thrill-seekers, venture to the nearby Lomas de Arena for sandboarding down breathtaking dunes, offering an exhilarating experience amidst striking landscapes.

Nightlife

In Santa Cruz, the vibrant nightlife features venues like Club Level, known for its lively atmosphere and diverse music, while La Bodeguita del Medio offers a relaxed vibe with live music and cocktails. Enjoy late-night dancing and socialising in the city's bustling bars and clubs.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, is perfect for cultural, family, and city-themed holidays. Visitors can explore national parks, stunning cathedrals, and vibrant squares. The area's attractions cater to those seeking cultural experiences, outdoor adventures, and thrilling activities. Consider visiting Santa Cruz de Tenerife, the Santa Cruz Wharf, or other local points of interest to enrich your stay.

  • Plaza 24 de Septiembre: This vibrant square serves as the heart of Santa Cruz, surrounded by lush trees and lively cafes. It’s a perfect spot to soak in the local culture, observe street performers, and mingle with residents, making it an ideal location for a leisurely afternoon.
  • Amboró National Park: A treasure for nature enthusiasts, this park offers breathtaking scenery and a variety of outdoor adventures. With diverse ecosystems and stunning landscapes, visitors can engage in hiking, birdwatching, and exploring unique flora and fauna.
  • San Lorenzo Cathedral: A striking example of colonial architecture, this cathedral features intricate details and a serene atmosphere. It’s an excellent place for reflection and to admire the artistic heritage that defines the region.

Best time to go to Santa Cruz

The best time to visit Santa Cruz is dependent on what kind of holiday you are seeking. October is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. June is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January78.3°F (25.7°C)Light RainMostly SunnySlightly LowAverage
February77.0°F (25.0°C)Light RainMostly CloudySlightly HighAverage
March76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
April74.5°F (23.6°C)Light RainMostly SunnyAverageSlightly High
May70.2°F (21.2°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnyAverageSlightly Low
August72.9°F (22.7°C)No RainSunnySlightly HighSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnyAverageSlightly High
November79.3°F (26.3°C)Light RainMostly SunnyAverageAverage
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowAverage

Explore a world of travel with Expedia

Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from ฿898 in a few different ways on Expedia. First, key in the dates you'd like to go on holiday, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ºC to 31ºC. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from ฿898 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favourite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveller experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Book your Santa Cruz hotel with Expedia and enjoy a world of options at unbeatable prices. Use our search filters to help you find exactly what you want, whether that's a 5-star escape or something a little more unique, like a houseboat, log cabin or villa! Join Expedia Rewards and you'll save 10% or more on over 100,000 hotels worldwide when you're signed in. Collect points on eligible bookings, which you can use to save on your next epic adventure. Plus, many of our hotels come with flexible cancellation policies, so you can rest easy if your plans happen to change.