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Santa Cruz Accommodation: Most Popular Cities to Stay

San Lorenzo Cathedral showing a garden
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Santa Cruz

Santa Cruz

Check prices for these dates

Tonight
8 Feb - 9 Feb
Tomorrow
9 Feb - 10 Feb
Next weekend
13 Feb - 15 Feb
In two weeks
20 Feb - 22 Feb

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Our top choices for Santa Cruz hotels

Seasonal outdoor pool

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (360 reviews)
"Welcoming clean rooms, friendly staff, continental breakfast with natural drinks "
United States
Victor
The price is ฿4,540
฿4,540 total
22 Feb - 23 Feb
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Outdoor pool, pool umbrellas, pool loungers

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (213 reviews)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ฿3,993
฿3,993 total
27 Feb - 28 Feb
Marriott Santa Cruz de la Sierra Hotel
Miscellaneous

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (85 reviews)
"Amazing breakfast "
United States
Sergio
The price is ฿1,558
฿1,558 total
12 Feb - 13 Feb
Ibis Santa Cruz DE LA Sierra
Outdoor pool

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (340 reviews)
"Awesome place "
Canada
John
The price is ฿3,064
฿3,064 total
13 Feb - 14 Feb
Sun Hotel
Reception

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (417 reviews)
"Rooms were very clean and service was excellent "
United States
JESUS
The price is ฿4,445
฿4,445 total
18 Feb - 19 Feb
Camino Real Hotel
Reception

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (42 reviews)
"Room was great and staff were very accommodating!"
Canada
David
HOTEL OSHO
Lobby sitting area

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (105 reviews)
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is ฿3,310
฿3,310 total
1 Mar - 2 Mar
Novotel Santa Cruz De La Sierra
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (83 reviews)
"Good price, great hotel!"
United States
James
The price is ฿1,230
฿1,230 total
10 Feb - 11 Feb
Premium Suites Deluxe Aparthotel Equipetrol
1 bedroom, in-room safe, desk, iron/ironing board

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (98 reviews)
"Yes, staff were very friendly "
United States
veronica
Apart Hotel Premium Suites Santa Cruz
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (260 reviews)
"Our room was clean and comfortable. The staff were friendly and very helpful!"
United States
Ann
The price is ฿2,320
฿2,320 total
13 Feb - 14 Feb
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Front of property

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (52 reviews)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
Chairú Eco Hotel
Outdoor pool, pool loungers

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (124 reviews)
"The staff and property are second to none! "
United States
Cynthia
The price is ฿3,972
฿3,972 total
24 Feb - 25 Feb
Hotel Cortez
Massages

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (82 reviews)
"Beautiful hotel"
Australia
Joanna
The price is ฿4,666
฿4,666 total
23 Feb - 24 Feb
Swissôtel Santa Cruz De La Sierra
Exterior detail

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (152 reviews)
"Yes! Room was spotless. The staff are very patient and professional. "
United States
Pluetina
The price is ฿3,121
฿3,121 total
10 Feb - 11 Feb
TRYP by Wyndham Santa Cruz
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (11 reviews)
"Perfect hotel"
Turkey
Yener
The price is ฿1,763
฿1,763 total
11 Mar - 12 Mar
Equipetrol Suites Apart Hotel
Daily buffet breakfast (USD 10 per person)

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (202 reviews)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol
Reception

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (32 reviews)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is ฿1,448
฿1,448 total
15 Feb - 16 Feb
Lido Hotel
Outdoor pool

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (78 reviews)
"Clean, well maintained and good customer service."
United States
Johnny
The price is ฿1,465
฿1,465 total
13 Feb - 14 Feb
Delfines Collection Hotel By Mercure
Standard Room, 2 Single Beds | Premium bedding, minibar, in-room safe, desk

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very good, (284 reviews)
"Clean, friendly staff"
United States
Giovanna
Hotel LP Santa Cruz Centro
Massages

Yotau All Suites Hotel

Yotau All Suites Hotel
3.5 star property
Santa Cruz
7.0 out of 10, Good, (76 reviews)
"I like everything "
United States
Sebastián
Yotau All Suites Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Santa Cruz

Showing deals for:20 Feb - 22 Feb

Image gallery for HOTEL OSHO

Junior Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar

HOTEL OSHO

3.5 star property
Santa Cruz
9.2/10Wonderful (42 reviews)
10% off
Price is ฿1,481
฿2,962 total
HOTEL OSHO
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Top Santa Cruz Hotel Reviews

Lido Hotel

Lido Hotel

10/10 Excellent
"We stayed at the fabulous Lido Hotel for 2 nights in December 2025. The hotel is located in central Santa Cruz, within a 4 block walk from Plaza 24 de Septiembre, and also a short 10 minute walk from the iconic Cristo Redentor statue. Check in was quick and painless, and the front desk staff was friendly and helpful. The room itself was spacious, clean and comfortable, with a large attached full bathroom. The air conditioner did a great job of cooling the room. Breakfast was served each morning in the attached Chinese restaurant, and featured eggs, breakfast meats, fruits, juices, cereal and yogurt, and was a great way to fuel up before venturing out to explore Santa Cruz. Without equivocation, I highly recommend the Lido Hotel to anyone in search of a clean comfortable hotel at an affordable price in the enchanting metrolopolis of Santa Cruz de la Sierra, Bolivia. Dr. Kingstone Shih and Laura Meneses Los Altos, California USA "
kingstone 2-night trip
Posted 1 month ago
Lido Hotel

Explore a world of travel with Expedia

Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from ฿1,230 in a few different ways on Expedia. First, key in the dates you'd like to go on holiday, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ºC to 31ºC. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from ฿1,230 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favourite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveller experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Book your Santa Cruz hotel with Expedia and enjoy a world of options at unbeatable prices. Use our search filters to help you find exactly what you want, whether that's a 5-star escape or something a little more unique, like a houseboat, log cabin or villa! Join Expedia Rewards and you'll save 10% or more on over 100,000 hotels worldwide when you're signed in. Collect points on eligible bookings, which you can use to save on your next epic adventure. Plus, many of our hotels come with flexible cancellation policies, so you can rest easy if your plans happen to change.