Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio Zoo Any Day Ticket
฿988
per adult
96% of travellers recommend
San Antonio: Witte Museum Admission Ticket
฿568
per adult
86% of travellers recommend
San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall
฿1,396
per adult
Dining at Hard Rock Cafe San Antonio
฿1,335
per traveller
76% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
฿1,068
per adult
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is ฿2,980 per night from 6 Oct to 7 Oct
฿2,980
฿3,522 total
6 Oct - 7 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is ฿3,128 per night from 5 Nov to 6 Nov
฿3,128
฿3,717 total
5 Nov - 6 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is ฿3,020 per night from 12 Oct to 13 Oct
฿3,020
฿3,570 total
12 Oct - 13 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,479 reviews)
"Good location food breakfast could have a little more variety."
Reviewed on 4 Oct 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is ฿3,292 per night from 12 Oct to 13 Oct
฿3,292
฿3,892 total
12 Oct - 13 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,009 reviews)
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Reviewed on 4 Oct 2026
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
The price is ฿5,028 per night from 19 Oct to 20 Oct
฿5,028
฿6,903 total
19 Oct - 20 Oct
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (3,160 reviews)
"We had an amazing stay!! The hotel is beautiful and the room was clean and very cozy. A must is dinner at Dorregos it was the best ribeye ive ever had!!"
Reviewed on 4 Oct 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is ฿2,990 per night from 18 Oct to 19 Oct
฿2,990
฿3,535 total
18 Oct - 19 Oct
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very good! (6,470 reviews)
"The place was a little dated and could use a some tlc. But it was clean and affordable and in a great section of town for accessing and enjoying the riverwalk and downtown area."
Reviewed on 4 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Uptown Central
If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
